Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joseph I Kliegman"'
Autor:
William B Ludington, Thaddeus D Seher, Olin Applegate, Xunde Li, Joseph I Kliegman, Charles Langelier, Edward R Atwill, Thomas Harter, Joseph L DeRisi
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174930 (2017)
BACKGROUND:Climate change produces extremes in both temperature and precipitation causing increased drought severity and increased reliance on groundwater resources. Agricultural practices, which rely on groundwater, are sensitive to but also sources
Externí odkaz:
https://doaj.org/article/67ecc086b801448fbfdd7e811b832acc
Autor:
Thaddeus D. Seher, Joseph I. Kliegman, Olin Applegate, Edward R. Atwill, Joseph L. DeRisi, William B. Ludington, Thomas Harter, Xunde Li, Charles Langelier
Publikováno v:
PloS one, vol 12, iss 4
PLoS ONE
Ludington, WB; Seher, TD; Applegate, O; Li, X; Kliegman, JI; Langelier, C; et al.(2017). Assessing biosynthetic potential of agricultural groundwater through metagenomic sequencing: A diverse anammox community dominates nitrate-rich groundwater. PLoS ONE, 12(4). doi: 10.1371/journal.pone.0174930. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2h11b468
PLoS ONE, Vol 12, Iss 4, p e0174930 (2017)
PLoS ONE
Ludington, WB; Seher, TD; Applegate, O; Li, X; Kliegman, JI; Langelier, C; et al.(2017). Assessing biosynthetic potential of agricultural groundwater through metagenomic sequencing: A diverse anammox community dominates nitrate-rich groundwater. PLoS ONE, 12(4). doi: 10.1371/journal.pone.0174930. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2h11b468
PLoS ONE, Vol 12, Iss 4, p e0174930 (2017)
© 2017 Ludington et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5096cfe4f3ef1a8361d062405160f09a
https://escholarship.org/uc/item/2h11b468
https://escholarship.org/uc/item/2h11b468
Publikováno v:
Biochemistry. 45:3493-3505
The manganese transport regulator (MntR) of Bacillus subtilis is activated by Mn(2+) to repress transcription of genes encoding transporters involved in the uptake of manganese. MntR is also strongly activated by cadmium, both in vivo and in vitro, b
Publikováno v:
Methods in enzymology. 548
Analog-sensitive AS Kinase technology allows for rapid, reversible, and highly specific inhibition of individual engineered kinases in cells and in mouse models of human diseases. The technique consists of two parts: a kinase containing a space-creat
Analog-sensitive AS Kinase technology allows for rapid, reversible, and highly specific inhibition of individual engineered kinases in cells and in mouse models of human diseases. The technique consists of two parts: a kinase containing a space-creat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8e4e202b2fbcb8f30f6a10bee00bcb9
https://doi.org/10.1016/b978-0-12-397918-6.00008-2
https://doi.org/10.1016/b978-0-12-397918-6.00008-2
Autor:
Trey Ideker, Pedro Beltrao, Elena Tosti, Chao Tang, Zongtian Tong, Colm J. Ryan, Nevan J. Krogan, Pádraig Cunningham, Harlizawati Jahari, Michael-Christopher Keogh, Winfried Edelmann, Assen Roguev, Lingli Jiang, J. Peter Svensson, Hong Qu, Kristin L. Patrick, Jiewei Xu, Hyun-Soo Kim, Christine Guthrie, Sean R. Collins, Michael Shales, Peter J. Espenshade, Kevan M. Shokat, Dwight Kuo, Derek Greene, Gerard Cagney, Joseph I. Kliegman
Publikováno v:
Molecular cell, vol 46, iss 5
To date, cross-species comparisons of genetic interactomes have been restricted to small or functionally related gene sets, limiting our ability to infer evolutionary trends. To facilitate a more comprehensive analysis, we constructed a genome-scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a460daa867f080a87624471998488925
https://escholarship.org/uc/item/9nn952fg
https://escholarship.org/uc/item/9nn952fg
Autor:
William E. Draper, Wendy A. Breyer, Rebecca K. Phillips, Kate E. Stoll, Seth M. Cohen, Richard G. Brennan, Howard F. Jenkinson, Joseph I. Kliegman, Hattie K. Brown, Rhoda A. T. Brew-Appiah, Nicholas S. Jakubovics, Misha V. Golynskiy, Arthur Glasfeld
Manganese is an essential nutrient for many pathogenic bacteria and has been linked to virulence in a number of species (1–3). A cofactor for a variety of enzymes involved in fighting oxidative stress, manganese is taken up in bacteria by NRAMP and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a54112d01e25140cdbe59cc9a19d6b
https://europepmc.org/articles/PMC3586275/
https://europepmc.org/articles/PMC3586275/
Autor:
Richard G. Brennan, John D. Helmann, David L. Farrens, Arthur Glasfeld, Joseph I. Kliegman, Mark A. DeWitt
Publikováno v:
Journal of molecular biology. 365(5)
The manganese transport regulator (MntR) from Bacillus subtilis binds cognate DNA sequences in response to elevated manganese concentrations. MntR functions as a homodimer that binds two manganese ions per subunit. Metal binding takes place at the in
Autor:
Ada Cheng, Max C. Caccese, Joseph I. Kliegman, Michael Shales, Dorothea Fiedler, David Thomas, Nevan J. Krogan, Colm J. Ryan, Xiaoyang Su, Yi-Fan Xu, Joshua D. Rabinowitz, Kevan M. Shokat
Publikováno v:
Cell reports, vol 5, iss 6
Cell Reports, Vol 5, Iss 6, Pp 1725-1736 (2013)
Cell Reports, Vol 5, Iss 6, Pp 1725-1736 (2013)
Current approaches for identifying synergistic targets use cell culture models with combinations of clinically available drugs to see if the combined effect of the combination is better than predicted by their individual efficacy. New techniques are
Autor:
Joseph I. Kliegman, Dorothea Fiedler, Colm J. Ryan, Yi-Fan Xu, Xiao-yang Su, David Thomas, Max C. Caccese, Ada Cheng, Michael Shales, Joshua D. Rabinowitz, Nevan J. Krogan, Kevan M. Shokat
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1725-1736 (2013)
Current approaches for identifying synergistic targets use cell culture models to see if the combined effect of clinically available drugs is better than predicted by their individual efficacy. New techniques are needed to systematically and rational
Externí odkaz:
https://doaj.org/article/6e8a50a061a746a3bc5414fd47db57d1