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Autor:
Yaohe Wang, Stephen Thorne, Joseph Hannock, Jennelle Francis, Tina Au, Tony Reid, Nick Lemoine, David Kirn, Gunnel Halldén
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(1)
Purpose: Replication-selective oncolytic adenoviruses hold promise for cancer treatment, but the predictive use of cell lines, dissociated tumor tissue, and animal models for efficacy against primary cancers are unclear. To further evaluate cytotoxic