Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Joseph Haimovich"'
Autor:
Nurit Hollander, Joseph Haimovich
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
B-cell antigen receptor (BCR) expression is indispensable for survival of most B-cell malignancies. In follicular lymphoma (FL), N-linked glycosylation sites are introduced in the immunoglobulin (Ig) variable region genes. Oligosaccharides added to t
Externí odkaz:
https://doaj.org/article/24c80084ba1240c9a824d4f54b426443
Publikováno v:
Molecular Immunology. 54:115-121
It has been recently demonstrated that while oligosaccharide moieties of μ heavy chains in the B-cell receptor (BCR) are of the complex type as expected, those of the pre-BCR on the surface of pre-B cells contain oligosaccharide moieties of the high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17faffd9ccf775f240d8fb62fba8c01a
https://doi.org/10.1016/j.molimm.2012.11.004
https://doi.org/10.1016/j.molimm.2012.11.004
Publikováno v:
Clinical and Experimental Immunology. 170:291-299
Summary The present standard of care for B cell non-Hodgkin's lymphoma includes the anti-CD20 monoclonal antibody rituximab. Although combination treatments with chemotherapy and rituximab improved the duration of remissions and overall survival in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59accc193a5d88bcf86faf5f35401ab7
https://doi.org/10.1111/j.1365-2249.2012.04658.x
https://doi.org/10.1111/j.1365-2249.2012.04658.x
Publikováno v:
The Journal of Immunology. 185:3239-3247
Rag-1 and Rag-2 are essential for the construction of the BCR repertoire. Regulation of Rag gene expression is tightly linked with BCR expression and signaling during B cell development. Earlier studies have shown a major role of the PI(3)K/Akt pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f27d179047495692d14ace449854d8d
https://doi.org/10.4049/jimmunol.1001430
https://doi.org/10.4049/jimmunol.1001430
Publikováno v:
Molecular Immunology. 47:1719-1727
Signal peptide-dependent insertion of newly synthesized proteins into the endoplasmic reticulum (ER) is a multi-step process, whose fidelity varies with the identity of the protein and the cell type. ER translocation of prions is sensitive to conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b56cd0a1f4d1ffa30aabe9fa99d8e4
https://doi.org/10.1016/j.molimm.2010.03.006
https://doi.org/10.1016/j.molimm.2010.03.006
Publikováno v:
Journal of Immunotherapy. 32:333-340
Indolent B-cell lymphomas are characterized by repeated remissions and relapses with most patients eventually dying of the disease. Although combination treatments with chemotherapy and the anti-CD20 antibody rituximab improved duration of remissions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8cebcdcfea3e9f387f4ed7e83548e0
https://doi.org/10.1097/cji.0b013e31819b7c17
https://doi.org/10.1097/cji.0b013e31819b7c17
Publikováno v:
Immunology & Cell Biology. 86:261-267
Immunoglobulins are expressed as membrane-bound or secreted forms. Plasma cells produce little or no membrane immunoglobulin but secrete immunoglobulin molecules in large amounts. Immunoglobulin idiotypes of malignant B cells are tumor-specific antig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56010982f8ecfa236d96836b3174bf33
https://doi.org/10.1038/sj.icb.7100153
https://doi.org/10.1038/sj.icb.7100153
Publikováno v:
Molecular and Cellular Biology. 26:1373-1385
The tetraspanin web is composed of a network of tetraspanins and their partner proteins that facilitate cellular interactions and fusion events by an unknown mechanism. Our aim was to unravel the web partnership between the tetraspanin CD81 and CD19,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aeae6d3363e352b3f26fa40a545f1d
https://doi.org/10.1128/mcb.26.4.1373-1385.2006
https://doi.org/10.1128/mcb.26.4.1373-1385.2006
Publikováno v:
Immunology Letters. 62:171-176
Adhesion molecules are involved in lymphoma dissemination. Antibodies to adhesion molecules may block tumor metastasis. However, such antibody treatment may block as well normal functions of the immune system. We tested the hypothesis that a bispecif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb59d3ce59dddf4e788ebcf557fed2b5
https://doi.org/10.1016/s0165-2478(98)00045-5
https://doi.org/10.1016/s0165-2478(98)00045-5
Publikováno v:
Journal of Immunological Methods. 214:113-119
A method based on surface plasmon resonance has been used to detect and to quantitate antibodies against other antibodies. This method has been applied to the detection of syngeneic antibodies. Concentrations as low as 0.3 microg/ml could be detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ed08ce526f9072b7f48d838e51342f
https://doi.org/10.1016/s0022-1759(98)00051-9
https://doi.org/10.1016/s0022-1759(98)00051-9