Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Joseph H. Su"'
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 1, Pp 165-173 (2007)
Neuronal degeneration linked to apoptosis can be inhibited by a family of proteins known as inhibitors of apoptosis proteins (IAPs). We examined three members of the IAP family that are implicated in the regulation of neuronal death. We assessed NAIP
Externí odkaz:
https://doaj.org/article/3e7aa7fbe68d48c28d156f91af0f9b53
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 245-252 (1998)
Expression of the growth arrest DNA damage-inducible protein,GADD45, has recently been reported to be induced by a wide range of stimuli, especially those that produce a high level of base pair damage. We have investigated the expression ofGADD45in b
Externí odkaz:
https://doaj.org/article/1c9f30b4f4624546a3de7ba18acee8f3
Publikováno v:
Neurobiology of Disease, Vol 4, Iss 5, Pp 365-375 (1997)
Neurofibrillary tangles and dystrophic neurites appear to develop in a highly characteristic spatial and temporal sequence in AD. In order to examine the nature of the cellular progression we have studied the trisynaptic entorhinal, dentate gyrus, CA
Externí odkaz:
https://doaj.org/article/bd356dcc60434e6f8218b4abcc9f9632
Autor:
Joseph H. Su, David H. Cribbs, Patrick Kesslack, Aileen J. Anderson, Carl W. Cotman, Liqi Tong, Christina H. Tu
Publikováno v:
Neurobiology of Disease, Vol 12, Iss 3, Pp 182-193 (2003)
It has recently been suggested that neuronal cell death in response to many brain insults may be mediated by the upregulation of tumor necrosis factor receptor (TNFR) family members and their ligands. In the present study, we investigated whether the
Autor:
Brian J. Cummings, Joseph H. Su, David H. Cribbs, Ming Zhao, Aileen J. Anderson, Andrea J. Wasserman, Carl W. Cotman
Publikováno v:
Neurochemical Research. 28:307-318
The tumor necrosis factor-alpha death domain pathway contributes to cellular degeneration in a variety of conditions. This study investigates the hypothesis that this death domain pathway is progressively induced in the brain during the progression o
Publikováno v:
Neurobiology of Aging. 22:195-207
To understand the extent and specificity of astrocyte pathology in sporadic frontotemporal dementia (FTD), we examined several FTD cases for molecular and morphologic characteristics of astrocyte degeneration. We quantified reactive and degenerating
Publikováno v:
Acta Neuropathologica. 96:463-471
Plaque-associated dystrophic neurites are a common pathological feature in the brains of patients with Alzheimer's disease (AD). In the present study, we investigated the relative abundance and progressive transformation of the amyloid precursor prot
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 245-252 (1998)
Expression of the growth arrest DNA damage-inducible protein, GADD45, has recently been reported to be induced by a wide range of stimuli, especially those that produce a high level of base pair damage. We have investigated the expression of GADD45 i
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 56:86-93
We have shown that many neurons in Alzheimer's disease (AD) exhibit terminal deoxynucleotidyl transferase (TdT) labeling for DNA strand breaks, and upregulation of Bcl-2 is associated with neurons exhibiting nuclear DNA fragmentation, while downregul
Publikováno v:
Brain Research. 739:79-87
Paired helical filament (PHF)/tau immunoreactive dystrophic neurites are a common pathological feature in the brain of patients with Alzheimer's disease. Recent studies suggest that swollen neurofilament-immunoreactive neurites are also present in se