Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Joseph H. Richardson"'
Autor:
Karina J. Yoon, Eddy S. Yang, James E. Bradner, Robert C.A.M. van Waardenburg, Xiangqin Cui, Joseph H. Richardson, Sushanth Reddy, Marty J. Heslin, J. Pablo Arnoletti, John D. Christein, Leona N. Council, Tracy L. Gamblin, Aubrey L. Miller, Patrick L. Garcia
Gene products downregulated greater than or equal to 2.4-fold by JQ1 in CCA1 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116db7fa964226bea971aeba3233213c
https://doi.org/10.1158/1535-7163.22505401
https://doi.org/10.1158/1535-7163.22505401
Autor:
Karina J. Yoon, Eddy S. Yang, James E. Bradner, Robert C.A.M. van Waardenburg, Xiangqin Cui, Joseph H. Richardson, Sushanth Reddy, Marty J. Heslin, J. Pablo Arnoletti, John D. Christein, Leona N. Council, Tracy L. Gamblin, Aubrey L. Miller, Patrick L. Garcia
Immunoblot analysis showing that JQ1 downregulates TEK, Chk1, MSH2 and LCK expression in CCA2 tumors, but not in CCA1 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a452940d6358b754c0626b806e616c
https://doi.org/10.1158/1535-7163.22505407
https://doi.org/10.1158/1535-7163.22505407
Autor:
Karina J. Yoon, Eddy S. Yang, James E. Bradner, Robert C.A.M. van Waardenburg, Xiangqin Cui, Joseph H. Richardson, Sushanth Reddy, Marty J. Heslin, J. Pablo Arnoletti, John D. Christein, Leona N. Council, Tracy L. Gamblin, Aubrey L. Miller, Patrick L. Garcia
Cholangiocarcinoma (CCA) is a fatal disease with a 5-year survival of Mol Cancer Ther; 17(1); 107–18. ©2017 AACR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ea64edc2cc4f4743db5ea2d516c24ea
https://doi.org/10.1158/1535-7163.c.6538042.v1
https://doi.org/10.1158/1535-7163.c.6538042.v1
Autor:
Patrick L Garcia, Leona N Council, John D Christein, J Pablo Arnoletti, Marty J Heslin, Tracy L Gamblin, Joseph H Richardson, Mary-Ann Bjornsti, Karina J Yoon
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78183 (2013)
Pancreatic cancer is the one of the deadliest of all malignancies. The five year survival rate for patients with this disease is 3-5%. Thus, there is a compelling need for novel therapeutic strategies to improve the clinical outcome for patients with
Externí odkaz:
https://doaj.org/article/1b49cc214efe4869a754ebeb935861fe
Autor:
Patrick L. Garcia, Aubrey L. Miller, Tracy L. Gamblin, Leona N. Council, John D. Christein, J. Pablo Arnoletti, Marty J. Heslin, Sushanth Reddy, Joseph H. Richardson, Xiangqin Cui, Robert C.A.M. van Waardenburg, James E. Bradner, Eddy S. Yang, Karina J. Yoon
Publikováno v:
Molecular Cancer Therapeutics. 17:107-118
Cholangiocarcinoma (CCA) is a fatal disease with a 5-year survival of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5597121ff518bad9c0bdd10352f418
https://doi.org/10.1158/1535-7163.mct-16-0922
https://doi.org/10.1158/1535-7163.mct-16-0922
Autor:
Thomas N. Wang, David T. Redden, Derek A. DuBay, Joseph H. Richardson, Peng Li, Laura Dover, Rojymon Jacob
Publikováno v:
The American Surgeon. 82:1133-1139
Intrahepatic cholangiocarcinoma (ICC) is classified according to the following subtypes: mass-forming (MF), periductal infiltrating (PI), and intraductal growth (IG). The aim of this study is to measure the association between ICC subtypes and patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec2397401e396049583a345bdd60b0ac
https://doi.org/10.1177/000313481608201132
https://doi.org/10.1177/000313481608201132
Autor:
Laura L, Dover, Rojymon, Jacob, Thomas N, Wang, Joseph H, Richardson, David T, Redden, Peng, Li, Derek A, DuBay
Publikováno v:
The American surgeon. 82(11)
Intrahepatic cholangiocarcinoma (ICC) is classified according to the following subtypes: massforming (MF), periductal infiltrating (PI), and intraductal growth (IG). The aim of this study is to measure the association between ICC subtypes and patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc4bbc2392451df1e6bc40bfa7db002e
https://pubmed.ncbi.nlm.nih.gov/28206944
https://pubmed.ncbi.nlm.nih.gov/28206944
Autor:
Carlo M. Contreras, Charles C. Weige, Carolyn E. Banister, Phillip Buckhaults, Erin L. Anderson, Joseph H. Richardson, Changlong Liu
Publikováno v:
Cancer Research. 77:B14-B14
We have performed a genome-wide screen for pathways that are synthetic lethal with TP53 mutations in colon cancer. RKO colon cancer cells are wild type for TP53, and display robust p53-dependent growth arrest and apoptosis. We utilized an isogenic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cf87822efab94d2201544a089fe976a
https://doi.org/10.1158/1538-7445.crc16-b14
https://doi.org/10.1158/1538-7445.crc16-b14
Autor:
Carlo M. Contreras, Charles C. Weige, Phillip Buckhaults, Erin L. Anderson, Joseph H. Richardson
Publikováno v:
Clinical Cancer Research. 23:B10-B10
We have performed a genome-wide synthetic lethal screen for pathways that are essential for the survival of colon cancer cells with TP53 mutations. RKO colon cancer cells are wild-type for TP53, and display robust p53-dependent growth arrest and apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c35fa93abaa0600a1863621e5c789d
https://doi.org/10.1158/1557-3265.pmccavuln16-b10
https://doi.org/10.1158/1557-3265.pmccavuln16-b10
Autor:
Patrick L. Garcia, Aubrey L. Miller, Kelly Kreitzburg, Tracy L. Gamblin, Leona N. Council, John D. Christein, Pablo Arnoletti, Marty Heslin, Sushanth Reddy, Joseph H. Richardson, Eddy S. Yang, Jun Qi, James E. Bradner, Karina J. Yoon
Publikováno v:
Cancer Research. 75:1779-1779
Cholangiocarcinoma (CCA) is a lethal malignancy of the biliary epithelium that can arise in any part of the biliary tree. Surgery is the only curative treatment for CCA, but only ∼30% of patients present with resectable disease. The remaining 70% o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e405f045fb877c988ddc2d63ada7fe84
https://doi.org/10.1158/1538-7445.am2015-1779
https://doi.org/10.1158/1538-7445.am2015-1779