Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joseph H Holthoff"'
Autor:
Catherine N Myers, Gary B Berner, Joseph H Holthoff, Kirby Martinez-Fonts, Jennifer A Harper, Sarah Alford, Megan N Taylor, Andrea A Duina
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20847 (2011)
In eukaryotic cells, the highly conserved FACT (FAcilitates Chromatin Transcription) complex plays important roles in several chromatin-based processes including transcription initiation and elongation. During transcription elongation, the FACT compl
Externí odkaz:
https://doaj.org/article/30f3960f889545f9b650ad8caa467726
Autor:
Joseph H. Holthoff, Yanping Harville, Christian Herzog, Luis A. Juncos, Nithin Karakala, John M. Arthur
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Acute kidney injury (AKI) is a major burden among hospitalized and critical care patients. Among hospitalized patients that progress to severe AKI there is increased risk for morbidity, mortality, and the need for renal replacemen
Externí odkaz:
https://doaj.org/article/f67aa707ca0a4a988de93ed9008c1efe
Publikováno v:
Kidney360
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb989485b4cfa72264a46d33d312f4f
https://europepmc.org/articles/PMC9802548/
https://europepmc.org/articles/PMC9802548/
Autor:
Joseph H. Holthoff, Horace J. Spencer, Elina Pathak, Zhen Wang, Neriman Gokden, Philip R. Mayeux, Kathryn A. Seely
Publikováno v:
The American Journal of Pathology. 180(2):505-516
Acute kidney injury is a frequent and serious complication of sepsis. To better understand the development of sepsis-induced acute kidney injury, we performed the first time-dependent studies to document changes in renal hemodynamics and oxidant gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ea90576dec5ebd9f43173fcd8e1f82
Autor:
Neriman Gokden, Zhen Wang, Samuel T. Burns, Joseph H. Holthoff, Kathryn A. Seely, Keshari M. Thakali, Sung W. Rhee, Philip R. Mayeux
Publikováno v:
American Journal of Physiology-Renal Physiology. 301:F209-F217
Sepsis is a leading cause of acute kidney injury (AKI) and mortality in children. Understanding the development of pediatric sepsis and its effects on the kidney are critical in uncovering new therapies. The goal of this study was to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a00852cab750e290bf8dd7e4095f941
https://doi.org/10.1152/ajprenal.00687.2010
https://doi.org/10.1152/ajprenal.00687.2010
Autor:
Philip R. Mayeux, Kurt J. Messer, Robert W. Brock, Joseph H. Holthoff, Neriman Gokden, Liping Wu, Manish M. Tiwari
Publikováno v:
American Journal of Physiology-Renal Physiology. 292:F261-F268
The mortality rate for septic patients with acute renal failure is extremely high. Since sepsis is often caused by lipopolysaccharide (LPS), a model of LPS challenge was used to study the development of kidney injury. Intravital video microscopy was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01b55b2cda16b3e65b91e6709e8e96a
https://doi.org/10.1152/ajprenal.00263.2006
https://doi.org/10.1152/ajprenal.00263.2006
Microcirculatory dysfunction is correlated with increased mortality among septic patients and is believed to be a major contributor to the development of acute kidney injury (AKI). Rolipram, a selective phosphodiesterase 4 (PDE4) inhibitor, has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7d8a723d678d82fab7af53b780abf4
https://europepmc.org/articles/PMC3807062/
https://europepmc.org/articles/PMC3807062/
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b4bfcc333dbaa0ff7eeec6d088ddc6
https://doi.org/10.1096/fasebj.26.1_supplement.1051.15
https://doi.org/10.1096/fasebj.26.1_supplement.1051.15
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872a640c61838e44527aad3ec02d64ef
https://doi.org/10.1096/fasebj.25.1_supplement.665.4
https://doi.org/10.1096/fasebj.25.1_supplement.665.4
Autor:
Philip R. Mayeux, Daniel R. Doerge, Kellie A. Woodling, Joseph H. Holthoff, Samuel T. Burns, Jack A. Hinson
Publikováno v:
Biochemical pharmacology. 80(8)
Oxidant damage from reactive oxygen species (ROS) and reactive nitrogen species (RNS) is a major contributor to the cellular damage seen in numerous types of renal injury. Resveratrol (trans-3,4',5-trihydroxystilbene) is a phytoalexin found naturally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5cc26427dcc3a7537725d3418d03ed
https://pubmed.ncbi.nlm.nih.gov/20599800
https://pubmed.ncbi.nlm.nih.gov/20599800