Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Joseph Gutkoska"'
Publikováno v:
Viruses, Vol 16, Iss 11, p 1657 (2024)
This study reports the use of Nanotrap® Microbiome A Particles (NMAPs) to capture and concentrate viruses from diluted suspensions to improve their recovery and sensitivity to detection by real-time PCR/RT-PCR (qPCR/RT-qPCR). Five highly infectious
Externí odkaz:
https://doaj.org/article/c13b4825ddf94903be7a4b5749ce5de6
Autor:
Gisselle N. Medina, Edward Spinard, Paul A. Azzinaro, Monica Rodriguez-Calzada, Joseph Gutkoska, Anna Kloc, Elizabeth A. Rieder, Bruce E. Taillon, Stephen Mueller, Teresa de los Santos, Fayna Diaz-San Segundo
Publikováno v:
Viruses, Vol 15, Iss 6, p 1332 (2023)
Foot-and-mouth disease (FMD), caused by the FMD virus (FMDV), is a highly contagious disease of cloven-hoofed livestock that can have severe economic impacts. Control and prevention strategies, including the development of improved vaccines, are urge
Externí odkaz:
https://doaj.org/article/d1b9122ebe054f7f92f32ace88ff628e
Autor:
Fayna Diaz-San Segundo, Gisselle N. Medina, Paul Azzinaro, Joseph Gutkoska, Aishwarya Mogulothu, Sarah E. Attreed, Kimberly R. Lombardi, Jacob Shields, Teresa A. Hudock, Teresa de los Santos
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Interferons (IFNs) are considered the first line of defense against viral diseases. Due to their ability to modulate immune responses, they have become an attractive therapeutic option to control virus infections. In fact, like many other viruses, fo
Externí odkaz:
https://doaj.org/article/8cf0e49df36c4455b9ff7da55c9d983c
Autor:
Carolina Stenfeldt, Jonathan Arzt, George Smoliga, Michael LaRocco, Joseph Gutkoska, Paul Lawrence
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-18 (2017)
Abstract Background Changes in the levels of circulating microRNAs (miRNAs) in the serum of humans and animals have been detected as a result of infection with a variety of viruses. However, to date, such a miRNA profiling study has not been conducte
Externí odkaz:
https://doaj.org/article/6b680f12ceba4538b761117dd3181bf9
Autor:
Segundo, Gisselle N. Medina, Edward Spinard, Paul A. Azzinaro, Monica Rodriguez-Calzada, Joseph Gutkoska, Anna Kloc, Elizabeth A. Rieder, Bruce E. Taillon, Stephen Mueller, Teresa de los Santos, Fayna Diaz-San
Publikováno v:
Viruses; Volume 15; Issue 6; Pages: 1332
Foot-and-mouth disease (FMD), caused by the FMD virus (FMDV), is a highly contagious disease of cloven-hoofed livestock that can have severe economic impacts. Control and prevention strategies, including the development of improved vaccines, are urge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::02d1e5413d41db6948715fb5c4944e96
Autor:
Kimberly R Lombardi, Teresa A Hudock, Jacob Shields, Gisselle N. Medina, Aishwarya Mogulothu, Paul A. Azzinaro, Joseph Gutkoska, Fayna Diaz-San Segundo, Teresa de los Santos, Sarah E Attreed
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology
Frontiers in Microbiology
Interferons (IFNs) are considered the first line of defense against viral diseases. Due to their ability to modulate immune responses, they have become an attractive therapeutic option to control virus infections. In fact, like many other viruses, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bf42bbde0fcf1a019281080fde6ae9
https://www.frontiersin.org/articles/10.3389/fmicb.2021.668890/full
https://www.frontiersin.org/articles/10.3389/fmicb.2021.668890/full
Autor:
Fayna Diaz-San Segundo, Ying Fang, Paul A. Azzinaro, Elizabeth Ramirez-Medina, Joseph Gutkoska, Teresa de los Santos, Gisselle N. Medina
Publikováno v:
Journal of Virology. 94
Foot-and-mouth disease virus (FMDV) leader proteinase (Lpro) affects several pathways of the host innate immune response. Previous studies in bovine cells demonstrated that deletions (leaderless [LLV]) or point mutations in Lpro result in increased e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3365023c47973eea622996a06aa168c2
https://doi.org/10.1128/jvi.00341-20
https://doi.org/10.1128/jvi.00341-20
Autor:
Gisselle N, Medina, Paul, Azzinaro, Elizabeth, Ramirez-Medina, Joseph, Gutkoska, Ying, Fang, Fayna, Diaz-San Segundo, Teresa, de Los Santos
Publikováno v:
Journal of Virology
In this study, we identified an aromatic hydrophobic residue in foot-and-mouth disease virus (FMDV) leader proteinase (Lpro) (W105) that is involved in the interaction with ISG15. Mutation in Lpro W105 (A12-LproW105A) resulted in reduced deISGylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c01c6d38292081fa6dac30e1222e81b
https://pubmed.ncbi.nlm.nih.gov/32295921
https://pubmed.ncbi.nlm.nih.gov/32295921
Autor:
Joseph Gutkoska, Carolina Stenfeldt, Michael LaRocco, Jonathan Arzt, George R. Smoliga, Paul Lawrence
Publikováno v:
Virology Journal
Virology Journal, Vol 14, Iss 1, Pp 1-18 (2017)
Virology Journal, Vol 14, Iss 1, Pp 1-18 (2017)
Background Changes in the levels of circulating microRNAs (miRNAs) in the serum of humans and animals have been detected as a result of infection with a variety of viruses. However, to date, such a miRNA profiling study has not been conducted for foo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0613632824f18e84b0802de6702cc1
http://europepmc.org/articles/PMC5384155
http://europepmc.org/articles/PMC5384155
Autor:
Teresa de los Santos, Paul Lawrence, Michael LaRocco, Joseph Gutkoska, Elizabeth Ramirez-Medina
Publikováno v:
Virology. 504
Sam68 was previously shown to be a critical host factor for foot-and-mouth disease virus (FMDV) replication. MicroRNA (miR) miR-203a is reportedly a negative regulator of Sam68 expression both in vitro and in vivo. Here, transfection of miR-203a-3p a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1273d13f0715c85b692ba202980f48
https://pubmed.ncbi.nlm.nih.gov/28152384
https://pubmed.ncbi.nlm.nih.gov/28152384