Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Joseph G. Turcotte"'
Autor:
Adrian L. Schwan, Michael D Gernon, Robert H. Notter, Joseph G. Turcotte, Min Wu, Jennifer L. Snelgrove, Yvonne Lear
Publikováno v:
Chemistry and Physics of Lipids. 101:215-222
This work compares two reaction schemes for preparing 2,3-bis(fattyalkylthio)-1-propanols for further synthetic adaptation as hydrophobic analogs of lung surfactant phosphatidylcholines. An attempt to prepare 2,3-bis(fattyalkylthio)-1-propanols based
Publikováno v:
Journal of Colloid and Interface Science. 173:471-477
Aqueous dispersions of dipalmitoyl phosphatidylcholine (DPPC), calf lung surfactant (LS) and an organic solvent extract of calf surfactant (CLSE) were examined by Fourier transform infrared (FTIR) spectroscopy in the presence and absence of calcium.
Publikováno v:
Langmuir. 11:101-107
Gel to liquid crystal transition temperatures (T c ) were measured by differential scanning calorimetry for a series of synthetic analogs of naturally occurring lung surfactant glycerophospholipids at pH 2.6, 5.6, and 11.5. Compounds all had equivale
Publikováno v:
Journal of Colloid and Interface Science. 167:378-390
Dynamic surface pressure-area (π-A) isotherms were measured for dipalmitoyl phosphatidylcholine (DPPC), dipalmitoyl phosphatidylethanolamine (DPPE), and 13 chain-equivalent synthetic phospholipid and phosphonolipid diether and etheramide analog comp
Publikováno v:
Journal of Colloid and Interface Science. 167:391-400
Dynamic respreading and maximum surface pressures are analyzed as a function of chain-backbone linkage, phosphatephosphonate group, and N-headgroup structure for surface-excess films of dipalmitoyl phosphatidylcholine (DPPC), dipalmitoyl phosphatidyl
Autor:
Robert H. Notter, Joseph G. Turcotte, T. Ueda, Machiko Ikegami, Alan H. Jobe, L Dizon-Co, W H Lin, Evelyn Rider
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 150:918-923
Increased phospholipase A2 activity demonstrated in some forms of lung injury may contribute to surfactant dysfunction. Phospholipase A2-resistant analogs of dipalmitoylphosphatidylcholine (DPPC) with surfactant properties might therefore be useful l
Publikováno v:
Journal of Liquid Chromatography. 16:2237-2248
Monophosphate diglyceride conjugate of AZT containing esterified saturated palmitoyl and unsaturated oleoyl fatty acid, a composition which more closely mimics the natural state (AZT-MP-DG). was synthesized. The purification of AZT-MP-DG from crude s
Publikováno v:
Journal of Colloid and Interface Science. 154:24-34
A series of synthetic analogs of naturally occurring glycerophospholipids has been studied for gel-to-liquid transition temperature (Tc) by using differential scanning calorimetry. The compounds investigated were dihexadecyl phosphatidylcholine (DHPC
Autor:
Robert H. Notter, Winnie H. Lin, Nankumar N. Bhongle, Joseph G. Turcotte, Nancy C. Motola, Zhong Lu, H.Robin Heyman, Shyam S. Shirali, Philip E. Pivarnik
Publikováno v:
Chemistry and Physics of Lipids. 58:81-95
A homologous series of chiral (R) ether-amide phosphonolipid analogs of naturally occurring (R) glycerophospholipids were synthesized and characterized for their interfacial behaviors. The phosphonolipids possess isoteric ether, amide, and phosphonat
Publikováno v:
Journal of Chromatography A. 517:219-228
Mixed-chain, multispecies, egg yolk-derived lecithin was isolated and purified on a silica column with isocratic elution. A method development column (20 x 0.46 cm I.D.) packed with YMC 15-30 microns, 120 A spherical silica and a mobile phase consist