Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joseph G. Beton"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cryo-EM experiments produce images of macromolecular assemblies that are combined to produce three-dimensional density maps. Typically, atomic models of the constituent molecules are fitted into these maps, followed by a density-guided refin
Externí odkaz:
https://doaj.org/article/5f1fe009c839496cbeae8fd241c93ad3
Autor:
Alice L. B. Pyne, Agnes Noy, Kavit H. S. Main, Victor Velasco-Berrelleza, Michael M. Piperakis, Lesley A. Mitchenall, Fiorella M. Cugliandolo, Joseph G. Beton, Clare E. M. Stevenson, Bart W. Hoogenboom, Andrew D. Bates, Anthony Maxwell, Sarah A. Harris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In cells, DNA is arranged into topologically-constrained (supercoiled) structures, but how this supercoiling affects the detailed double-helical structure of DNA remains unclear. Here authors use atomic force microscopy and atomistic molecular dynami
Externí odkaz:
https://doaj.org/article/728c1ae4dbb4491c9742de5d69efdcab
Autor:
Erin C Johnston, Bart W. Hoogenboom, Bernd Bukau, Jim Monistrol, Helen R. Saibil, Anne S. Wentink, Joseph G. Beton, Anthony J. Roberts
SummaryAlthough amyloid fibres are highly stable protein aggregates, a specific combination of human Hsp70 system chaperones can disassemble them, including fibres formed of α-synuclein, huntingtin or Tau. Disaggregation requires the ATPase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83080ed4e0a5d0fa943bc8afb00b57e9
https://doi.org/10.1101/2021.08.29.458036
https://doi.org/10.1101/2021.08.29.458036
Autor:
Agnes Noy, Anthony Maxwell, Alice L. B. Pyne, Kavit Main, Michael M. Piperakis, Joseph G. Beton, Bart W. Hoogenboom, Clare E. M. Stevenson, Victor Velasco-Berrelleza, Fiorella M. Cugliandolo, Sarah A. Harris, Lesley A. Mitchenall, Andrew D. Bates
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled) structures. It remains unclear how this supercoiling affects the detailed double-helical structure of DNA, largely because of limitations in spatial resolu
Autor:
Luzie Helfmann, Bart W. Hoogenboom, Agnel Praveen Joseph, Robert Moorehead, Maya Topf, Alice L. B. Pyne, Joseph G. Beton, Robert Gray
Publikováno v:
Methods (San Diego, Calif.)
Highlights • TopoStats is a Python toolkit for automated AFM data processing. • TopoStats takes raw data as input, and outputs processed data and statistical information without user input. • TopoStats can accurately trace linear and circular b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c331e0abb7dc1ff4c1cf0f0a2510e844
https://doi.org/10.1101/2020.09.23.309609
https://doi.org/10.1101/2020.09.23.309609
Autor:
Clare E. M. Stevenson, Lesley A. Mitchenall, Alice L. B. Pyne, Kavit Main, Anthony Maxwell, Joseph G. Beton, Sarah A. Harris, Bart W. Hoogenboom, Agnes Noy, Victor Velasco-Berrelleza, Fiorella M. Cugliandolo, Michael M. Piperakis, Andrew D. Bates
In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled) structures. It remains unclear how this supercoiling affects the detailed double-helical structure of DNA, largely because of limitations in spatial resolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e630f42c1141cf1b86c1483853509e98
https://doi.org/10.1101/863423
https://doi.org/10.1101/863423