Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joseph G. Arthur"'
Autor:
Zhana Duren, Wenhui Sophia Lu, Joseph G. Arthur, Preyas Shah, Jingxue Xin, Francesca Meschi, Miranda Lin Li, Corey M. Nemec, Yifeng Yin, Wing Hung Wong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Changes in cell state underlie the difference between health and disease. Here, the authors propose a computational framework for the integration of gene expression and chromatin-accessibility data from single cells to identify differences in gene re
Externí odkaz:
https://doaj.org/article/9c4fc70938c445fdbe6641ebdbf16cd2
Autor:
Christopher Hughes, Bo Zhou, Joseph G. Arthur, Taeyoung Kim, Giltae Song, Dean Palejev, Wing H. Wong, Alexander E. Urban
Publikováno v:
European Neuropsychopharmacology. 63:e177-e178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b033b18ac6b00a6678fa3d7945f9be5
https://doi.org/10.1016/j.euroneuro.2022.07.322
https://doi.org/10.1016/j.euroneuro.2022.07.322
Autor:
Wing Hung Wong, Preyas Shah, Yifeng Yin, Jingxue Xin, Wenhui Sophia Lu, Miranda Lin Li, Zhana Duren, Francesca Meschi, Joseph G. Arthur, Corey M. Nemec
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
The comparison of gene regulatory networks between diseased versus healthy individuals or between two different treatments is an important scientific problem. Here, we propose sc-compReg as a method for the comparative analysis of gene expression reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022d1eab3724640520ce4b15a7b0f7b4
https://doi.org/10.1038/s41467-021-25089-2
https://doi.org/10.1038/s41467-021-25089-2
Publikováno v:
Applied Mathematics and Computation. 316:155-166
The use of Kalman filtering, as well as its nonlinear extensions, for the estimation of system variables and parameters has played a pivotal role in many fields of scientific inquiry where observations of the system are restricted to a subset of vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166d8e39c3051afd0d537af94f0022d4
https://doi.org/10.1016/j.amc.2017.08.002
https://doi.org/10.1016/j.amc.2017.08.002
Autor:
Jeffrey A. Hussmann, Jonathan S. Weissman, Jessica M. Terry, Joseph G. Arthur, Jin Chen, Luigi J. Alvarado, Tarjei S. Mikkelsen, Thomas M. Norman, Joseph M. Replogle, Ian T. Fiddes, Daniel Riordan, Britt Adamson, Albert Xu, Niranjan Srinivas, Katherine Pfeiffer, Elliott Meer, J. Zachery Cogan
Publikováno v:
Nature biotechnology
Nature biotechnology, vol 38, iss 8
Nature biotechnology, vol 38, iss 8
Single-cell CRISPR screens enable the exploration of mammalian gene function and genetic regulatory networks. However, use of this technology has been limited by reliance on indirect indexing of single-guide RNAs (sgRNAs). Here we present direct-capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1415edd61d9e7bfc9833c353c2a63492
https://pubmed.ncbi.nlm.nih.gov/32231336
https://pubmed.ncbi.nlm.nih.gov/32231336
Autor:
Reenal Pattni, Yiling Huang, Bo Zhou, Wing Hung Wong, Joseph G. Arthur, Steve S. Ho, Alexander E. Urban
Publikováno v:
Scientific Data
We produced an extensive collection of deep re-sequencing datasets for the Venter/HuRef genome using the Illumina massively-parallel DNA sequencing platform. The original Venter genome sequence is a very-high quality phased assembly based on Sanger s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58f5b3511c2863558fcec260ab2768f
http://europepmc.org/articles/PMC6298255
http://europepmc.org/articles/PMC6298255
Autor:
Gisli Masson, Anna Helgadottir, Brynjar O. Jensson, Runolfur Palsson, Aimee M. Deaton, Erna V. Ivarsdottir, Daniel F. Gudbjartsson, Vinicius Tragante, Snaedis Kristmundsdottir, Olafur S. Indridason, Stefania Benonisdottir, Gardar Sveinbjornsson, Gerald Sulem, Isleifur Olafsson, Gudny A. Arnadottir, Pall T. Onundarson, Birte Kehr, Bjarni V. Halldorsson, Thorunn Rafnar, Gunnar Sigurdsson, Ragnar P. Kristjansson, Folkert W. Asselbergs, Asmundur Oddsson, Kari Stefansson, Vidar O. Edvardsson, Rafn Benediktsson, Gudmundur I. Eyjolfsson, Valgerdur Steinthorsdottir, Hrafnhildur Linnet Runolfsdottir, Hilma Holm, Patrick Sulem, Joseph G. Arthur, Astradur B. Hreidarsson, Evgenia Mikaelsdottir, Bjarni Gunnarsson, Gudmar Thorleifsson, Olafur B. Davidsson, Unnur Thorsteinsdottir
Publikováno v:
Human Molecular Genetics
Publisher´s version (útgefin grein)
Urine dipstick tests are widely used in routine medical care to diagnose kidney and urinary tract and metabolic diseases. Several environmental factors are known to affect the test results, whereas the effec
Urine dipstick tests are widely used in routine medical care to diagnose kidney and urinary tract and metabolic diseases. Several environmental factors are known to affect the test results, whereas the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e2db6197e10965dba0dfc402e6296f
https://hdl.handle.net/20.500.11815/2082
https://hdl.handle.net/20.500.11815/2082
Autor:
Reenal Pattni, Seunggyu Byeon, Bo Zhou, Hanlee P. Ji, Ishan Saha, Xiaowei Zhu, John Bell, Giltae Song, Alexander E. Urban, Alexej Abyzov, Dimitri Perrin, Xianglong Zhang, Steve S. Ho, Stephanie U. Greer, Noah Spies, Wing H. Wong, Yiling Huang, Joseph G. Arthur
Publikováno v:
Nucleic Acids Research
HepG2 is one of the most widely used human cell lines in biomedical research and one of the main cell lines of ENCODE. Although the functional genomic and epigenomic characteristics of HepG2 are extensively studied, its genome sequence has never been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b488ad4eed186db131fde37ed65e19
https://doi.org/10.1101/378497
https://doi.org/10.1101/378497
A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin
Autor:
Hilma Holm, Asmundur Oddsson, Kari Stefansson, Gudmundur L. Norddahl, Ragnar P. Kristjansson, Gisli H. Halldorsson, Gisli Masson, Gudjon R. Oskarsson, Brynjar O. Jensson, Daniel F. Gudbjartsson, Erna V. Ivarsdottir, Jona Saemundsdottir, Stefania Benonisdottir, Gudny A. Arnadottir, Isleifur Olafsson, Pall T. Onundarson, Gardar Sveinbjornsson, Olafur B. Davidsson, Amy L. Lee, Magnus K. Magnusson, Unnur Thorsteinsdottir, Patrick Sulem, Joseph G. Arthur
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-7 (2018)
The cytokine erythropoietin (EPO), signalling through the EPO receptor (EPO-R), is essential for the formation of red blood cells. We performed a genome-wide association study (GWAS) testing 32.5 million sequence variants for association with serum E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6119aaeedfbaa68ebb20248af9290be0
https://doi.org/10.1038/s42003-018-0053-3
https://doi.org/10.1038/s42003-018-0053-3
Publikováno v:
European Neuropsychopharmacology. 29:S163-S164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4df6816f3e39f746ed3170524d5ed256
https://doi.org/10.1016/j.euroneuro.2019.08.097
https://doi.org/10.1016/j.euroneuro.2019.08.097