Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joseph G Dolan"'
Autor:
Pamela Aubert, Mayte Suárez-Fariñas, Hiroshi Mitsui, Leanne M Johnson-Huang, Jamie Lynn Harden, Katherine C Pierson, Joseph G Dolan, Inna Novitskaya, Israel Coats, Jacob Estes, Edward W Cowen, Nicole Plass, Chyi-Chia Richard Lee, Hong-Wei Sun, Michelle A Lowes, Raphaela Goldbach-Mansky
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49408 (2012)
The autoinflammatory disorder, Neonatal-onset Multisystem Inflammatory Disease (NOMID) is the most severe phenotype of disorders caused by mutations in CIAS1 that result in increased production and secretion of active IL-1β. NOMID patients present w
Externí odkaz:
https://doaj.org/article/8a9aeb4526b5468588188cde3238cfac
Autor:
Sarah E. Henrickson, Joseph G. Dolan, Lisa R. Forbes, Alexander Vargas-Hernández, Shiho Nishimura, Satoshi Okada, Leslie S. Kersun, Garrett M. Brodeur, Jennifer R. Heimall
Publikováno v:
Frontiers in Pediatrics, Vol 7 (2019)
In this report, we describe a novel T437N STAT1 mutation found in a mother and 3 of her 4 children which we demonstrate yields gain-of-function. All of the four patients with the T437N STAT1 mutation experienced lymphadenopathy. However, two of the c
Externí odkaz:
https://doaj.org/article/77ca43005b864a82b04fa619b58daa1d
Publikováno v:
Expert Rev Clin Immunol
INTRODUCTION: Though 85% of children and young adults with acute lymphoblastic leukemia (ALL) are cured, the prognosis of relapsed or refractory disease is poor, with little progress made until recently. The advent of chimeric antigen receptor (CAR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1468fde1bc61176a4f5535e1e065f5f3
https://doi.org/10.1080/1744666x.2021.1828067
https://doi.org/10.1080/1744666x.2021.1828067
Autor:
Regina M. Myers, Yimei Li, Amanda M. DiNofia, Susan R. Rheingold, Colleen Callahan, Diane Baniewicz, Haley Newman, Hongyan Liu, Richard Aplenc, Joseph G Dolan, Lisa Wray, Stephan A. Grupp, Carl H. June, Shannon L. Maude, Kaitlin Devine, Allison Barz Leahy
Publikováno v:
Lancet Haematol
Summary Background CNS relapse of acute lymphocytic leukaemia is difficult to treat. Durable remissions of relapsed or refractory B-cell acute lymphocytic leukaemia have been observed following treatment with CD19-directed chimeric antigen receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5e000dc47396161eb2eb424256f10
https://pubmed.ncbi.nlm.nih.gov/34715045
https://pubmed.ncbi.nlm.nih.gov/34715045
Autor:
Regina McGuire, Julie C. Fitzgerald, Diane Baniewicz, Lisa Wray, Colleen Callahan, Allison Barz Leahy, Whitney L. Gladney, Stephan Kadauke, Regina M. Myers, Joseph G Dolan, Laura S Motley, Hongyan Liu, Yimei Li, David M. Barrett, Gerald Wertheim, Simon F. Lacey, David T. Teachey, Stephan A. Grupp, Richard Aplenc, Shannon L. Maude, Amanda M. DiNofia
Publikováno v:
J Clin Oncol
PURPOSETo prospectively evaluate the effectiveness of risk-adapted preemptive tocilizumab (PT) administration in preventing severe cytokine release syndrome (CRS) after CTL019, a CD19 chimeric antigen receptor T-cell therapy.METHODSChildren and young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe0103a6c8c8963bec55077e5d83089
https://pubmed.ncbi.nlm.nih.gov/33417474
https://pubmed.ncbi.nlm.nih.gov/33417474
Autor:
Joseph G. Dolan, Garrett M. Brodeur, Shiho Nishimura, Lisa R. Forbes, Sarah E. Henrickson, Jennifer Heimall, Satoshi Okada, Leslie S. Kersun, Alexander Vargas-Hernández
Publikováno v:
Frontiers in Pediatrics
Frontiers in Pediatrics, Vol 7 (2019)
Frontiers in Pediatrics, Vol 7 (2019)
In this report, we describe a novel T437N STAT1 mutation found in a mother and 3 of her 4 children which we demonstrate yields gain-of-function. All of the four patients with the T437N STAT1 mutation experienced lymphadenopathy. However, two of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a471014ced77c02abd739f9b8380e64
https://doi.org/10.3389/fped.2019.00160
https://doi.org/10.3389/fped.2019.00160
Autor:
Yimei Li, Regina M. Myers, Joseph G. Dolan, Haley Newman, Stephan A. Grupp, Susan R. Rheingold, Hongyan Liu, Kaitlin Devine, Lisa Wray, Colleen Callahan, Shannon L. Maude, Amanda M. DiNofia, Carl H. June, Allison Barz Leahy
Publikováno v:
Journal of Clinical Oncology. 38:10511-10511
10511 Background: CNS relapse of B-ALL is difficult to treat after cranial radiation or multiple relapses. Durable remissions of relapsed/refractory (r/r) B-ALL have been seen with CD19 CAR T cells; however, most trials excluded patients with active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71180401f96f6eec5327303dc171fc5b
https://doi.org/10.1200/jco.2020.38.15_suppl.10511
https://doi.org/10.1200/jco.2020.38.15_suppl.10511
Autor:
Patrick Kicker, Joseph G. Dolan, Zachary Phillips, Joseph Snow, Christopher K. Zalewski, Frank Pucino, Cailin H. Sibley, N. Plass, Edythe Wiggs, John A. Butman, Christopher Snyder, Scott M. Paul, Kelly A. King, Robert Wesley, Dawn Chapelle, Raphaela Goldbach-Mansky, Brigitte C. Widemann, H. Jeffrey Kim, Nalini Jayaprakash, Deborah L. Stone, Carmen C. Brewer, Rachel Bishop, Suvimol Hill
Publikováno v:
Arthritis & Rheumatism. 64:2375-2386
Neonatal-onset multisystem inflammatory disease (NOMID; also known as chronic infantile neurologic, cutaneous, articular syndrome) (MIM 607115) is the most severe clinical phenotype of a spectrum of autoinflammatory disorders caused by autosomal domi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4afd793bef86bb1dcc72a56386cca1
https://doi.org/10.1002/art.34409
https://doi.org/10.1002/art.34409
Autor:
Sandra Burkett, Vu N. Ngo, Su Young Kim, Xiaolin Wan, Joseph G. Dolan, Javed Khan, Choh Yeung, Louis M. Staudt, Lee J. Helman
Publikováno v:
Cancer research. 72(22)
We identified Bub1b as an essential element for the growth and survival of rhabdomyosarcoma (RMS) cells using a bar-coded, tetracycline-inducible short hairpin RNA (shRNA) library screen. Knockdown of Bub1b resulted in suppression of tumor growth in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acffe6f1bf8d9e55318581a9ba3fbe7f
https://pubmed.ncbi.nlm.nih.gov/23002205
https://pubmed.ncbi.nlm.nih.gov/23002205
Autor:
Jamie L. Harden, Israel Coats, Raphaela Goldbach-Mansky, Chyi-Chia Richard Lee, Jacob D. Estes, Hong-Wei Sun, Leanne M. Johnson-Huang, Joseph G. Dolan, Michelle A. Lowes, Mayte Suárez-Fariñas, Hiroshi Mitsui, Nicole Plass, Inna Novitskaya, Pamela Aubert, Edward W. Cowen, Katherine C. Pierson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49408 (2012)
PLoS ONE
PLoS ONE
The autoinflammatory disorder, Neonatal-onset Multisystem Inflammatory Disease (NOMID) is the most severe phenotype of disorders caused by mutations in CIAS1 that result in increased production and secretion of active IL-1β. NOMID patients present w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0fb370c27111ebbe3926c08e880a5f
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23226210/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23226210/?tool=EBI