Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Joseph Flores"'
Publikováno v:
Jurnal Kesehatan Lingkungan, Vol 16, Iss 3, Pp 222-228 (2024)
Introduction: Houseflies serve as vectors of diseases in animals and humans. Chemical pesticides are a practical way of eliminating insects; however, resistance to insecticides has been reported. This study aims to evaluate the adulticidal efficacy o
Externí odkaz:
https://doaj.org/article/6a6c2082a9ce43dc80e12101933a2c43
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-13 (2022)
Abstract Human genetic and animal model studies indicate that brain microglial inflammation is a primary driver of cognitive impairment in Alzheimer Disease (AD). Inflammasome-activated Caspase-1 (Casp1) is associated with both AD microglial inflamma
Externí odkaz:
https://doaj.org/article/fddd8aa2303c47b297863e96df229950
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Previous work showed that the caspase 1 inhibitor VX-765 rescued cognitive deficits in the J20 mouse model of Alzheimer’s disease, and this may occur via reduced inflammation. Here the authors show that administration of the drug prior to onset of
Externí odkaz:
https://doaj.org/article/f9e708e8e4a94657bdc8e388bc81fd42
Autor:
Libin Zhou, Joseph Flores, Anastasia Noël, Olivier Beauchet, P. Jesper Sjöström, Andrea C. LeBlanc
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Activated Caspase-6 (Casp6) is associated with age-dependent cognitive impairment and Alzheimer disease (AD). Mice expressing human Caspase-6 in hippocampal CA1 neurons develop age-dependent cognitive deficits, neurodegeneration and neuroinf
Externí odkaz:
https://doaj.org/article/485d6f972eff467a8be1a38aa3a0acaa
Autor:
Joseph Flores, Anastasia Noël, Bénédicte Foveau, Jeffrey Lynham, Clotilde Lecrux, Andréa C. LeBlanc
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Caspase-1, activated by stress in immune cells and in CNS human neurons, may contribute to neuronal degeneration. Here, the authors investigate the therapeutic potential of a Caspase-1 inhibitor in a mouse model of Alzheimer’s disease.
Externí odkaz:
https://doaj.org/article/2ab3ce42e3eb4a95a13cf8e46e06bf48
Autor:
Joseph Flores-Toro, Sung-Kook Chun, Jun-Kyu Shin, Joan Campbell, Melissa Lichtenberger, William Chapman, Ivan Zendejas, Kevin Behrns, Christiaan Leeuwenburgh, Jae-Sung Kim
Publikováno v:
Cells, Vol 10, Iss 8, p 1863 (2021)
Ischemia/reperfusion (I/R) injury unavoidably occurs during hepatic resection and transplantation. Aged livers poorly tolerate I/R during surgical treatment. Although livers have a powerful endogenous inhibitor of calpains, calpastatin (CAST), I/R ac
Externí odkaz:
https://doaj.org/article/d6f175025177486ebd446a0122556724
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22789-7
Externí odkaz:
https://doaj.org/article/86037b7173504cdf9304f0d21b898ae2
Autor:
Licup, Bianca Patricia E., Purnamasari, Listya, Olarve, Joseph Penano, dela Cruz, Joseph Flores
Publikováno v:
Journal of Environmental Health / Jurnal Kesehatan Lingkungan; Jul2024, Vol. 16 Issue 3, p222-228, 7p
Publikováno v:
Buletin Peternakan; Vol 47, No 1 (2023): BULETIN PETERNAKAN VOL. 47 (1) FEBRUARY 2023; 30-35
The study aimed to investigate the effect of beta-mannanase supplementation on growth performance, fecal consistency, and carcass characteristics of weanling pigs. A total of 100 weaned piglets (initial body weight = 7 ± 0.5 kg) were divided into 2
Strike-slip fault systems consist of a variety of geometrical complexities like branches, kinks and step-overs. Especially, the presence of a step-over structure can strongly determine the final size of the earthquake rupture. Thus understanding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1666989153aec0fefcfa9bc0fad9b58e
https://doi.org/10.5194/egusphere-egu23-15695
https://doi.org/10.5194/egusphere-egu23-15695