Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph F. Lawler"'
Autor:
Alexander Turchin, Joseph F. Lawler
Publikováno v:
BioTechniques, Vol 26, Iss 4, Pp 672-676 (1999)
Site-directed mutagenesis is a powerful tool that has enabled molecular biologists to perform functional analysis of altered nucleic acids and proteins. Newer PCR-based mutagenesis techniques have reduced the process of mutagenesis to as little as on
Externí odkaz:
https://doaj.org/article/297d468c9e684985857c48c370a0a6c7
Publikováno v:
Neurology. 93(13)
A 50-year-old woman with a history of fibromuscular dysplasia presented to the emergency department with 1 day of right ear pain. Examination demonstrated 2 mm anisocoria, left pupil larger than right, with brisk pupillary light reactions bilaterally
Autor:
Wei Wei, Eric M. Ostertag, Siew Loon Ooi, Nicolas Gilbert, Haig H. Kazazian, Jef D. Boeke, Joseph F. Lawler, John V. Moran
Publikováno v:
Molecular and Cellular Biology. 21:1429-1439
Long interspersed nuclear elements (LINEs or L1s) comprise approximately 17% of human DNA; however, only about 60 of the approximately 400,000 L1s are mobile. Using a retrotransposition assay in cultured human cells, we demonstrate that L1-encoded pr
Autor:
Margaret S. Halleck, Robert A. Schlegel, Jason T. Newman, Priya Nagarajan, Hiroshi Ando, Yoshinobu Nakanishi, Coleen Hacker, Daniel Weinstock, Ling Gao, Patrick Williamson, Joseph F. Lawler, Scott Pyle, Seth Blackshaw
Publikováno v:
ResearcherID
Halleck, Margaret S., Joseph F. Lawler, Jr., Seth Blackshaw, Ling Gao, Priya Nagarajan, Coleen Hacker, Scott Pyle, Jason T. Newman, Yoshinobu Nakanishi, Hiroshi Ando, Daniel Weinstock, Patrick Williamson, and Robert A. Schlegel. Differential expressi
Autor:
Christopher A. Ross, J. Timothy Greenamyre, Solomon H. Snyder, Joseph F. Lawler, Alan H. Sharp, Gordon W. Wiegand, Jillian K. Cooper, Akira Sawa, Russell L. Margolis
Publikováno v:
Nature Medicine. 5:1194-1198
Huntington disease (HD) is a genetically dominant condition caused by expanded CAG repeats coding for glutamine in the HD gene product huntingtin1. Although HD symptoms reflect preferential neuronal death in specific brain regions, huntingtin is expr
Publikováno v:
eLS
Reporter genes are easily measured surrogates for a molecule of interest. Keywords: counterselection; fluorescence; screening; selection
Autor:
Frederick, Levy, Joseph F, Lawler
Publikováno v:
Journal of health care lawpolicy. 6(2)
Retrotransposition of the Ty1 element of Saccharomyces cerevisiae is temperature sensitive. Transposition activity of Ty1 is abolished at temperatures above 34°C. In this report, we show that the major block to transposition at high temperature is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1ed67260079e671574fb66371c0d03
https://europepmc.org/articles/PMC155059/
https://europepmc.org/articles/PMC155059/
Publikováno v:
Journal of virology. 76(1)
Ty1 is the most successful of the five endogenous yeast retrotransposons. The life cycle of Ty1 dictates that a number of nucleocapsid (NC)-facilitated events occur although the protein(s) responsible for these events has not been identified. The pos
Publikováno v:
Journal of virology. 75(15)
The yeast retrotransposon Ty1 encodes a 7-nucleotide RNA sequence that directs a programmed, +1 ribosomal frameshifting event required for Gag-Pol translation and retrotransposition. We report mutations that block frameshifting, which can be suppress