Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joseph F. Hudner"'
Autor:
Joseph F. Hudner, Graham S. Macaulay, Robert A. Stockman, Timothy Harvey, Charles R. White, Roderick John Dorgan, David Lathbury, Lewis Norman John, David O. Morgan, Nigel Hussain, Ian P. Andrews
Publikováno v:
Tetrahedron Letters. 37:4811-4814
A 6-step synthesis of the potent anthelmintic SB-201561 is described. The key stage of the synthesis is a novel Beckmann type oxime fragmentation to give a lactone, followed by a 2-step reassembly of the spirolcetal moiety.
Autor:
Geoffrey Harold Baker, Nigel Hussain, Joseph F. Hudner, David O. Morgan, Roderick John Dorgan
Publikováno v:
Tetrahedron Letters. 35:2385-2388
The lactone intermediates (2) and (3) are converted by lithium acetylide chemistry followed by mercury catalysed hydration to novel semi-synthetic 23-oxo C24 and C25 substituted milbemycins (7).
Autor:
Roderick John Dorgan, Nigel Hussain, Joseph F. Hudner, David O. Morgan, Geoffrey Harold Baker
Publikováno v:
ChemInform. 25