Výsledky vyhledávání - "Joseph F LaComb"

Akademický článek

AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor.

Autor: Komala Ingle, Joseph F LaComb, Lee M Graves, Antonio T Baines, Agnieszka B Bialkowska

Publikováno v: PLoS ONE, Vol 18, Iss 11, p e0294065 (2023)

Pancreatic cancer is one of the leading causes of cancer deaths, with pancreatic ductal adenocarcinoma (PDAC) being the most common subtype. Advanced stage diagnosis of PDAC is common, causing limited treatment opportunities. Gemcitabine is a frequen

Externí odkaz: https://doaj.org/article/e3eb0d2776e742fe88ffa94c8c131237

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Akademický článek

Longitudinal microbiome analysis of single donor fecal microbiota transplantation in patients with recurrent Clostridium difficile infection and/or ulcerative colitis.

Autor: Michael Mintz, Shanawaj Khair, Suman Grewal, Joseph F LaComb, Jiyhe Park, Breana Channer, Ramona Rajapakse, Juan Carlos Bucobo, Jonathan M Buscaglia, Farah Monzur, Anupama Chawla, Jie Yang, Charlie E Robertson, Daniel N Frank, Ellen Li

Publikováno v: PLoS ONE, Vol 13, Iss 1, p e0190997 (2018)

Studies of colonoscopic fecal microbiota transplant (FMT) in patients with recurrent CDI, indicate that this is a very effective treatment for preventing further relapses. In order to provide this service at Stony Brook University Hospital, we initia

Externí odkaz: https://doaj.org/article/83751a52b10d4b48865e2a64523331db

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Akademický článek

Correction: Aberrant DNA Methylation: Implications in Racial Health Disparity.

Autor: Xuefeng Wang, Ping Ji, Yuanhao Zhang, Joseph F LaComb, Xinyu Tian, Ellen Li, Jennie L Williams

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0158251 (2016)

[This corrects the article DOI: 10.1371/journal.pone.0153125.].

Externí odkaz: https://doaj.org/article/c706fbbc1aaa453a979bf5b7701109f1

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Akademický článek

Aberrant DNA Methylation: Implications in Racial Health Disparity.

Autor: Xuefeng Wang, Ping Ji, Yuanhao Zhang, Joseph F LaComb, Xinyu Tian, Ellen Li, Jennie L Williams

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153125 (2016)

Incidence and mortality rates of colorectal carcinoma (CRC) are higher in African Americans (AAs) than in Caucasian Americans (CAs). Deficient micronutrient intake due to dietary restrictions in racial/ethnic populations can alter genetic and molecul

Externí odkaz: https://doaj.org/article/14cdba6a40924102b3b1d9e27f2a81d9

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Intestinal Epithelial Regeneration in Response to Ionizing Irradiation

Autor: Agnieszka B. Bialkowska, Vincent W. Yang, Michael Giarrizzo, Joseph F. LaComb, Emilia J. Orzechowska-Licari

Publikováno v: Journal of visualized experiments : JoVE. (185)

The intestinal epithelium consists of a single layer of cells yet contains multiple types of terminally differentiated cells, which are generated by the active proliferation of intestinal stem cells located at the bottom of intestinal crypts. However

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ffc46b349bef0099613d85d3fa7be7
https://pubmed.ncbi.nlm.nih.gov/35969101

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Supplemental Figures from Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

Autor: David A. Tuveson, Steven Gallinger, Alexander Krasnitz, Jennifer Knox, Richard Moffitt, Julie M. Wilson, Sandra E. Fischer, Benjamin Hubert, Christopher R. Vakoc, Ellen Li, Kenneth H. Yu, Christopher L. Wolfgang, Allyson Ocean, Craig Devoe, James M. Crawford, Edward Kim, Faiyaz Notta, Grainne M. O'Kane, Michael A. Hollingsworth, Jonathan R. Brody, Paul M. Grandgenett, Jonathan M. Buscaglia, Dominick J. DiMaio, Jean L. Grem, Phyllis A. Gimotty, Jordan M. Winter, James D. Sullivan, William Nealon, Divyesh V. Sejpal, Peter Allen, Juan Carlos Bucobo, Maoxin Wu, Joseph Kim, Aaron Sasson, Brian M. Wolpin, Andrew J. Aguirre, Elizabeth Thompson, Ralph H. Hruban, Laura D. Wood, Hans Clevers, Christine A. Iacobuzio-Donahue, Gokce Askan, Nicolas LeComte, Else Driehuis, Laura Martello, Cinthya Y. Lowder, Austin B. Goetz, Rashesh Sanghvi, Minita Shah, Nicolas Robine, Kanika Arora, Molly Johnson, Jasmine C. Huynh, Ammar A. Javed, Randze Lerie D. Palmaira, Joseph F. LaComb, Michelle Ma, Hardik Patel, C. Megan Young, Koji Miyabayashi, Gun-Ho Jang, Robert E. Denroche, Richard A. Burkhart, Fieke E. M. Froeling, Tim D. D. Somerville, Astrid Deschênes, Dennis Plenker, Dannielle D. Engle, Pascal Belleau, Hervé Tiriac

Supplemental Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4b9db9fc893e295d2cada7f880c78f
https://doi.org/10.1158/2159-8290.22533064.v1

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Table S3 from Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

Table S3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a90dd220ac0ec32817c28c76958ed3
https://doi.org/10.1158/2159-8290.22533052

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Supplemental Table Legends from Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

Supplemental Table Legends

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510326c43d97558246f493acd659e4be
https://doi.org/10.1158/2159-8290.22533061.v1

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5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In Vitro

Autor: Vanessa M. Diaz Almanzar, Kunal Shah, Joseph F. LaComb, Aisharja Mojumdar, Hetvi R. Patel, Jacky Cheung, Meiyi Tang, Jingfang Ju, Agnieszka B. Bialkowska

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3954

Chronic pancreatitis is characterized by chronic inflammation and fibrosis, processes heightened by activated pancreatic stellate cells (PSCs). Recent publications have demonstrated that miR-15a, which targets YAP1 and BCL-2, is significantly downreg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c12dcbaff62b52a8ff8854981f0bb94

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