Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joseph F Cardiello"'
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307375 (2024)
Heat shock stress induces genome-wide changes in transcription regulation, activating a coordinated cellular response to enable survival. We noticed many heat shock genes are up-regulated in blood samples from individuals with trisomy 21. We characte
Externí odkaz:
https://doaj.org/article/e9b62ee5f1034911aaaac0be0f2acd27
Autor:
Joseph F. Cardiello, Alberto Joven Araus, Sarantis Giatrellis, András Simon, Nicholas D. Leigh
Single cell sequencing technologies (scRNA-seq, scATAC-seq, etc.) have revolutionized the study of complex tissues and unique organisms, providing researchers with a much needed species agnostic tool to study biological processes at the cellular leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dde1896bca7ba79f4b5037c314c7625b
https://doi.org/10.1101/2022.09.22.508993
https://doi.org/10.1101/2022.09.22.508993
Publikováno v:
Transcription
Nascent transcription assays, such as global run-on sequencing (GRO-seq) and precision run-on sequencing (PRO-seq), have uncovered a myriad of unstable RNAs being actively produced from numerous sites genome-wide. These transcripts provide a more com
Publikováno v:
Molecular and cellular biology. 38(18)
Cellular transcriptional programs are tightly controlled but can profoundly change in response to environmental challenges or stress. Here we describe global changes in mammalian RNA polymerase II (Pol II) occupancy at mRNA genes in response to heat
Autor:
Joseph F. Cardiello, Todd N. Rosenstiel, Alison J. Fisher, Michaelin G. Richards, Alexandra T. Lantz, Taylor A. Gee
Publikováno v:
Plant Physiology and Biochemistry. 94:209-215
Each year, plants emit terragram quantities of the reactive hydrocarbon isoprene (2-methyl-1,3-butadiene) into the earth's atmosphere. In isoprene-emitting plants, the enzyme isoprene synthase (ISPS) catalyzes the production of isoprene from the isop
The control of transcriptional pathways during the cell cycle is paramount to regulating cell growth and differentiation, and maintaining cells in a non-cancerous state. Human CGGBP1 (CGG triplet repeat-binding protein 1) was first identified as a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19234ea5270892021e988bbe377d0611
https://europepmc.org/articles/PMC4614046/
https://europepmc.org/articles/PMC4614046/
Autor:
Namitha Manoj, Shruti Padhee, Jianfeng Cai, Yaqiong Li, Qiao Qiao, Chuanhai Cao, Christina Smith, Haifan Wu, Hang Yin, Joseph F Cardiello
Publikováno v:
ACS chemical biology. 9(1)
Antimicrobial peptides (AMPs) are host-defense agents capable of both bacterial membrane disruption and immunomodulation. However, the development of natural AMPs as potential therapeutics is hampered by their moderate activity and susceptibility to
Autor:
Joseph F Cardiello, Alberto Joven Araus, Sarantis Giatrellis, Clement Helsens, András Simon, Nicholas D Leigh
Single-cell sequencing (sc-seq) provides a species agnostic tool to study cellular processes. However, these technologies are expensive and require sufficient cell quantities and biological replicates to avoid artifactual results. An option to addres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64e8db6f5843d12d5db48f25e7a4526
https://infoscience.epfl.ch/record/303082
https://infoscience.epfl.ch/record/303082