Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Joseph F, Krzyzaniak"'
A Comparison of Methods for Computing Relative Anhydrous–Hydrate Stability with Molecular Simulation
Autor:
Eric C. Dybeck, Andrew Thiel, Michael J. Schnieders, Frank C. Pickard, Geoffrey P.F. Wood, Joseph F. Krzyzaniak, Bruno C. Hancock
Publikováno v:
Crystal Growth & Design. 23:142-167
Autor:
Bhushan Munjal, Kevin DeBoyace, Fengjuan Cao, Joseph F. Krzyzaniak, Kapildev K. Arora, Raj Suryanarayanan
Publikováno v:
Molecular Pharmaceutics.
Autor:
Chamara A. Gunawardana, Angela Kong, Debbie Wanapun, Daniel O. Blackwood, C. Travis Powell, Joseph F. Krzyzaniak, Myles C. Thomas, John E. Kresevic, Changquan Calvin Sun
Publikováno v:
International Journal of Pharmaceutics. 640:123016
Autor:
Chamara A, Gunawardana, Angela, Kong, Daniel O, Blackwood, C, Travis Powell, Joseph F, Krzyzaniak, Myles C, Thomas, Changquan, Calvin Sun
Publikováno v:
International Journal of Pharmaceutics. 630:122422
Scanning electron microscopy-based energy dispersive X-ray spectroscopy (SEM-EDS) is proposed as a versatile tool for quantifying surface area coverage (SAC) by magnesium stearate (MgSt) on pharmaceutical tablets and particles. Our approach involved
Autor:
Michael J. Zaworotko, Shawn M. LaCasse, Joseph F. Krzyzaniak, Kapildev K. Arora, Naga Kiran Duggirala
Publikováno v:
Crystal Growth & Design. 20:617-626
Phase transformation of an active pharmaceutical ingredient in the solid state can influence the physicochemical properties and consequently drug product performance. The neat cocrystal of Ertuglif...
Autor:
Barry John Aldous, Ernest H. H. Chow, Mark D. Eddleston, Joseph F. Krzyzaniak, William Jones, Mihails Arhangelskis, Ranjit Thakuria, Kashyap Kumar Sarmah
Publikováno v:
Organic Process Research & Development. 23:845-851
Caffeine–glutaric acid cocrystal polymorphs, Form I and Form II, are presented as a model system to study cocrystal dissociation under controlled humidity. On the basis of relative humidity (RH) data, it was observed that Form I transforms to Form
Publikováno v:
Crystal Growth & Design. 19:868-875
The stability of theophylline cocrystals composed of acidic (glutaric acid), basic (isonicotinamide), or neutral (benzamide) coformers was evaluated in the presence of several excipients. Tablets of theophylline-glutaric acid (TG) and theophylline-is
Autor:
Joseph F. Krzyzaniak, Lydie Louis, Bruno C. Hancock, Paul Meenan, Kapildev K. Arora, Ayana Ghosh, Serge Nakhmanson, Geoffrey P. F. Wood
Publikováno v:
CrystEngComm. 21:1215-1223
In the current report, three machine learning approaches were assessed for their ability to predict the crystallization propensities of a set of small organic compounds (
Autor:
Lisa J. Taylor, Brendan J. Murphy, Paul Meenan, Joseph F. Krzyzaniak, Neil Dawson, Changquan Calvin Sun, Shubhajit Paul, Matthew P. Mullarney
Publikováno v:
Molecular pharmaceutics. 17(4)
Punch sticking during tablet manufacturing is a common problem facing the pharmaceutical industry. Using several model compounds, effects of crystal size and shape of active pharmaceutical ingredients (API) on punch sticking propensity were systemati
Autor:
Suman Luthra, Kapildev K. Arora, Sheri L. Shamblin, Joseph F. Krzyzaniak, Mitulkumar A. Patel, Lynne S. Taylor
Publikováno v:
Crystal Growth & Design. 18:7027-7040
Salt disproportionation is a major issue for pharmaceutical products containing a salt form of a weakly basic drug, because conversion to the free base during processing or storage in the presence of excipients may negatively impact stability and bio