Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Joseph E. Willis"'
Autor:
Ali Vaziri-Gohar, Jonathan J. Hue, Ata Abbas, Hallie J. Graor, Omid Hajihassani, Mehrdad Zarei, George Titomihelakis, John Feczko, Moeez Rathore, Sylwia Chelstowska, Alexander W. Loftus, Rui Wang, Mahsa Zarei, Maryam Goudarzi, Renliang Zhang, Belinda Willard, Li Zhang, Adam Kresak, Joseph E. Willis, Gi-Ming Wang, Curtis Tatsuoka, Joseph M. Salvino, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is highly resistant to chemotherapy. Effective alternative therapies have yet to emerge, as chemotherapy remains the best available systemic treatment. However, the discovery of safe and available adju
Externí odkaz:
https://doaj.org/article/d2faef86ea85483498c70286f6d2ac00
Autor:
Matthew A. Devall, Xiangqing Sun, Stephen Eaton, Gregory S. Cooper, Joseph E. Willis, Daniel J. Weisenberger, Graham Casey, Li Li
Publikováno v:
Cancers, Vol 15, Iss 1, p 45 (2022)
Approximately 90% of colorectal cancer (CRC) develop over the age of 50, highlighting the important role of aging in CRC risk. African Americans (AAs) shoulder a greater CRC burden than European Americans (EA) and are more likely to develop CRC at a
Externí odkaz:
https://doaj.org/article/8c0de69971fd4eaab4b3817865b726d1
Autor:
E. Georg Luebeck, Kit Curtius, William D. Hazelton, Sean Maden, Ming Yu, Prashanthi N. Thota, Deepa T. Patil, Amitabh Chak, Joseph E. Willis, William M. Grady
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-10 (2017)
Abstract Background Recent studies have identified age-related changes in DNA methylation patterns in normal and cancer tissues in a process that is called epigenetic drift. However, the evolving patterns, functional consequences, and dynamics of epi
Externí odkaz:
https://doaj.org/article/98577dabbc1e4e40b76e727b3863035f
Autor:
Yujun Hao, Yardena Samuels, Qingling Li, Dawid Krokowski, Bo-Jhih Guan, Chao Wang, Zhicheng Jin, Bohan Dong, Bo Cao, Xiujing Feng, Min Xiang, Claire Xu, Stephen Fink, Neal J. Meropol, Yan Xu, Ronald A. Conlon, Sanford Markowitz, Kenneth W. Kinzler, Victor E. Velculescu, Henri Brunengraber, Joseph E. Willis, Thomas LaFramboise, Maria Hatzoglou, Guo-Fang Zhang, Bert Vogelstein, Zhenghe Wang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Cancer cells rely on glutamine to replenish the TCA cycle. Here, the authors show that oncogenic PIK3CAmutations drive this metabolic rewiring in colorectal cancer cells by up-regulating glutamate pyruvate transaminase expression, thus increasing sen
Externí odkaz:
https://doaj.org/article/906e6679c4cc4a669a5f8d6f4ee9c634
Autor:
Charlems Alvarez-Jimenez, Jacob T. Antunes, Nitya Talasila, Kaustav Bera, Justin T. Brady, Jayakrishna Gollamudi, Eric Marderstein, Matthew F. Kalady, Andrei Purysko, Joseph E. Willis, Sharon Stein, Kenneth Friedman, Rajmohan Paspulati, Conor P. Delaney, Eduardo Romero, Anant Madabhushi, Satish E. Viswanath
Publikováno v:
Cancers, Vol 12, Iss 8, p 2027 (2020)
(1) Background: The relatively poor expert restaging accuracy of MRI in rectal cancer after neoadjuvant chemoradiation may be due to the difficulties in visual assessment of residual tumor on post-treatment MRI. In order to capture underlying tissue
Externí odkaz:
https://doaj.org/article/7786b091ae1f4a469685223415ed4b2c
Autor:
Ming Yu, Helen R. Moinova, Amber Willbanks, Victoria K. Cannon, Ting Wang, Kelly Carter, Andrew Kaz, Deepti Reddi, John Inadomi, Georg Luebeck, Prasad G. Iyer, Marcia I. Canto, Jean S. Wang, Nicholas J. Shaheen, Prashanti N. Thota, Joseph E. Willis, Thomas LaFramboise, Amitabh Chak, Sanford D. Markowitz, William M. Grady
Publikováno v:
Clin Cancer Res
Purpose: Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this highly letha
Autor:
Joseph E, Willis, Frederick, Eyerer, Eric E, Walk, Patricia, Vasalos, Georganne, Bradshaw, Sophia Louise, Yohe, Jordan S, Laser
Publikováno v:
Archives of Pathology & Laboratory Medicine. 147:62-70
Context.— Programmed death ligand-1 (PD-L1) immunohistochemistry companion diagnostic assays play a crucial role as predictive markers in patients being considered for immune checkpoint inhibitor therapy. However, because of a convergence of severa
Autor:
Amitabh Chak, Wendy Brock, James M. Warfe, Apoorva Chandar, Sanford D. Markowitz, Kishore Guda, Joseph E. Willis, Ye D. Tian, Julian A. Abrams, Prasad G. Iyer, Jean S. Wang, Nicholas J. Shaheen, Marcia Canto, Sumeet K. Mittal, Ashley Faulx, William M. Grady, Gary W. Falk, Jill S. Barnholtz-Sloan, Robert C. Elston, Xiangqing Sun
The relationship of age and date of birth (DOB) in the data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2af4ff4335ced3302a7244aa0e00f7
https://doi.org/10.1158/1055-9965.22436986
https://doi.org/10.1158/1055-9965.22436986
Autor:
Amitabh Chak, Wendy Brock, James M. Warfe, Apoorva Chandar, Sanford D. Markowitz, Kishore Guda, Joseph E. Willis, Ye D. Tian, Julian A. Abrams, Prasad G. Iyer, Jean S. Wang, Nicholas J. Shaheen, Marcia Canto, Sumeet K. Mittal, Ashley Faulx, William M. Grady, Gary W. Falk, Jill S. Barnholtz-Sloan, Robert C. Elston, Xiangqing Sun
Background: Barrett's esophagus is often asymptomatic and only a small portion of Barrett's esophagus patients are currently diagnosed and under surveillance. Therefore, it is important to develop risk prediction models to identify high-risk individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df4d0267e7d35a9b5d6ea39baedca80
https://doi.org/10.1158/1055-9965.c.6515653.v1
https://doi.org/10.1158/1055-9965.c.6515653.v1
Autor:
Amitabh Chak, Wendy Brock, Sanford Markowitz, Joseph E. Willis, Sumeet K. Mittal, Margaret Kinnard, William M. Grady, Gary Falk, Jill Barnholtz-Sloan, Robert Elston, Xiangqing Sun
Supplementary Table 2 from A Segregation Analysis of Barrett's Esophagus and Associated Adenocarcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d60b7facf3c52695408374d0b58147f
https://doi.org/10.1158/1055-9965.22435680.v1
https://doi.org/10.1158/1055-9965.22435680.v1