Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joseph E. Prince"'
Autor:
Stephen H. Gregory, Chirayu Shah, C. Wayne Smith, Joseph E. Prince, Huaizhu Wu, Daniel Zeve, Christie M. Ballantyne, Cory Brayton
Publikováno v:
Infection and Immunity. 71:5986-5993
Mice with targeted mutations of CD18, the common β2 subunit of CD11/CD18 integrins, have leukocytosis, impaired transendothelial neutrophil emigration, and reduced host defense toStreptococcus pneumoniae, a gram-positive extracellular bacterium. Pre
Autor:
Felix R. Shardonofsky, Huifang Lu, David B. Corry, Arthur L. Beaudet, Lynn Soong, Seung-Hyo Lee, Farrah Kheradmand, C. Wayne Smith, Muhammad Rais, Joseph E. Prince
Publikováno v:
Nature Medicine. 9:1281-1286
To understand the integrin requirements of T-helper (T(H)) effector subsets, we investigated the contribution of CD18 (beta(2) integrin) to T(H)1 and T(H)2 function in vitro and in relevant disease models. CD18-deficient (Itgb2(-/-)) T cells showed l
Publikováno v:
Emerging Therapeutic Targets. 3:263-277
Autor:
Gabriele Weitz-Schmidt, Seung-Hyo Lee, C. Wayne Smith, David B. Corry, Joseph E. Prince, Muhammad Rais, Farrah Kheradmand, Christie M. Ballantyne
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(7)
Integrin CD18, a component of the LFA-1 complex that also includes CD11a, is essential for Th2, but not Th1, cell homing, but the explanation for this phenomenon remains obscure. In this study, we investigate the mechanism by which Th2 effector respo
Autor:
Yasunori Abe, Xiaoyuan Dai Perrard, Greg Dietsch, Huaizhu Wu, Joseph E. Prince, Beckley K. Davis, Christie M. Ballantyne, C. Wayne Smith, Jerry L. Perrard, John R. Rodgers
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(1)
The β2 integrin CD11a is involved in T cell-APC interactions, but the roles of CD11b, CD11c, and CD11d in such interactions have not been examined. To evaluate the roles of each CD11/CD18 integrin in T cell-APC interactions, we tested the ability of
Publikováno v:
The Journal of allergy and clinical immunology. 111
This review summarizes the recent advances regarding pathogenesis, diagnosis, and treatment of immunological diseases of the lung. Rather than attempt a comprehensive analysis, we have focused on selected diseases that are of particular relevance to
Autor:
Cory Brayton, Christie M. Ballantyne, Joseph E. Prince, Sheldon L. Kaplan, J. A. Durand, C. W. Smith, M. C. Fossett
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 166(12)
Mice deficient in CD18, which lack all four CD11 integrins, have leukocytosis and increased susceptibility to bacterial infection. To determine the effect of deficiencies in LFA-1 (CD11a/CD18) or Mac-1 (CD11b/CD18) on host defense against systemic ba