Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Joseph E. Mazurkiewicz"'
Publikováno v:
Brain Sciences, Vol 3, Iss 2, Pp 615-626 (2013)
In developing neurons the frequency of long duration, spontaneous, transient calcium (Ca2+) elevations localized to the growth cone, is inversely related to the rate of axon elongation and increases several fold when axons pause. Here we report that
Externí odkaz:
https://doaj.org/article/acd38c6d854844e7aa94a0963de1a69d
The phenotypic switching called epithelial-to-mesenchymal transition is frequently associated with epithelial tumor cell progression from a comparatively benign to an aggressive, invasive malignancy. Coincident with the emergence of such cellular pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd062b83a2669eb263bb7a5464915c6
https://doi.org/10.1158/0008-5472.c.6499847.v1
https://doi.org/10.1158/0008-5472.c.6499847.v1
Supplementary Video 2C from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9c018bab52b198c59cbedbd96dd49e
https://doi.org/10.1158/0008-5472.22381364.v1
https://doi.org/10.1158/0008-5472.22381364.v1
Supplementary Figure 2 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94768d9b4fb2b3677d9380b18d342ccd
https://doi.org/10.1158/0008-5472.22381376
https://doi.org/10.1158/0008-5472.22381376
Supplementary Figure 4 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5722b9af4636b3dcfa661c1bf7da212f
https://doi.org/10.1158/0008-5472.22381370
https://doi.org/10.1158/0008-5472.22381370
Supplementary Figure 3 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308bbfff8b5b3d564fb0d1d48915c22f
https://doi.org/10.1158/0008-5472.22381373
https://doi.org/10.1158/0008-5472.22381373
Supplementary Figure 1 from TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3020a6992bade9391c9e1f9f3b46ccb6
https://doi.org/10.1158/0008-5472.22381379
https://doi.org/10.1158/0008-5472.22381379
Autor:
Alena Rudkouskaya, Marien Ochoa, Xavier Intes, Joseph E. Mazurkiewicz, Nattawut Sinsuebphon, Margarida Barroso, Sez-Jade Chen
Publikováno v:
Theranostics
Rationale: Following an ever-increased focus on personalized medicine, there is a continuing need to develop preclinical molecular imaging modalities to guide the development and optimization of targeted therapies. Near-Infrared (NIR) Macroscopic Flu
Autor:
Xinjun Cindy Zhu, Matthew A. Adamo, Joseph E. Mazurkiewicz, Ramkumar Mathur, Mahabub Maraj Alam, Xiao-Feng Zhao, Yuan Liao, Yunfei Huang, Paul J. Feustel
Publikováno v:
J Neurosci
Excessive activation of mammalian target of rapamycin (mTOR) signaling is epileptogenic in genetic epilepsy. However, the exact role of microglial mTOR in acquired epilepsy remains to be clarified. In the present study, we found that mTOR is strongly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96da5a52a3209ad17fded8aba9a6e243
https://europepmc.org/articles/PMC7531547/
https://europepmc.org/articles/PMC7531547/
Autor:
Paul J. Feustel, Gary W. Mathern, Yunfei Huang, Xiao-Feng Zhao, Matthew A. Adamo, Michael Gruenthal, Xinjun Zhu, Joseph E. Mazurkiewicz, Julia W. Chang, Jiang Qian, Anthony L. Ritaccio, Shannon Morgan, Ramkumar Mathur, Yuan Liao
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2080-2093 (2018)
Cell reports
Cell reports, vol 22, iss 8
Cell reports
Cell reports, vol 22, iss 8
Summary Microglia are well known to play a critical role in maintaining brain homeostasis. However, their role in epileptogenesis has yet to be determined. Here, we demonstrate that elevated mTOR signaling in mouse microglia leads to phenotypic chang