Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joseph E Grossman"'
Autor:
Bruno Bockorny, Lakshmi Muthuswamy, Ling Huang, Marco Hadisurya, Christine Maria Lim, Leo L Tsai, Ritu R Gill, Jesse L Wei, Andrea J Bullock, Joseph E Grossman, Robert J Besaw, Supraja Narasimhan, Weiguo Andy Tao, Sofia Perea, Mandeep S Sawhney, Steven D Freedman, Manuel Hildago, Anton Iliuk, Senthil K Muthuswamy
Publikováno v:
eLife, Vol 12 (2024)
Pancreatic cancer has the worst prognosis of all common tumors. Earlier cancer diagnosis could increase survival rates and better assessment of metastatic disease could improve patient care. As such, there is an urgent need to develop biomarkers to d
Externí odkaz:
https://doaj.org/article/2fbf0bf62bc64eee832a7920b461d554
Autor:
Manuel Hidalgo, Rocio Garcia-Carbonero, Kian-Huat Lim, Wells A. Messersmith, Ignacio Garrido-Laguna, Erkut Borazanci, Andrew M. Lowy, Laura Medina Rodriguez, Daniel Laheru, Beatriz Salvador-Barbero, Marcos Malumbres, David J. Shields, Joseph E. Grossman, Xin Huang, Meggan Tammaro, Jean-François Martini, Yanke Yu, Kenneth Kern, Teresa Macarulla
Publikováno v:
Cancer Research Communications. 2:1326-1333
Purpose: To assess the preclinical efficacy, clinical safety and efficacy, and MTD of palbociclib plus nab-paclitaxel in patients with advanced pancreatic ductal adenocarcinoma (PDAC). Experimental Design: Preclinical activity was tested in patient-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ee14ce29f5739213957260f92451a25
https://doi.org/10.1158/2767-9764.crc-22-0072
https://doi.org/10.1158/2767-9764.crc-22-0072
Autor:
David M. Faleck, Michael Dougan, Monique Tello, Joseph E. Grossman, Alan C. Moss, Michael A. Postow
Publikováno v:
Journal of Clinical Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cddd68b5f01a8a496fadf5d4ed912bf9
https://doi.org/10.1200/jco.22.02914
https://doi.org/10.1200/jco.22.02914
Autor:
Teresa Macarulla, Kenneth Kern, Yanke Yu, Jean-François Martini, Meggan Tammaro, Xin Huang, Joseph E. Grossman, David J. Shields, Marcos Malumbres, Beatriz Salvador-Barbero, Daniel Laheru, Laura Medina Rodriguez, Andrew M. Lowy, Erkut Borazanci, Ignacio Garrido-Laguna, Wells A. Messersmith, Kian-Huat Lim, Rocio Garcia-Carbonero, Manuel Hidalgo
Purpose:To assess the preclinical efficacy, clinical safety and efficacy, and MTD of palbociclib plus nab-paclitaxel in patients with advanced pancreatic ductal adenocarcinoma (PDAC).Experimental Design:Preclinical activity was tested in patient-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7649524ba3fef20e3a6a23a96f904fc9
https://doi.org/10.1158/2767-9764.c.6550848.v1
https://doi.org/10.1158/2767-9764.c.6550848.v1
Autor:
Teresa Macarulla, Kenneth Kern, Yanke Yu, Jean-François Martini, Meggan Tammaro, Xin Huang, Joseph E. Grossman, David J. Shields, Marcos Malumbres, Beatriz Salvador-Barbero, Daniel Laheru, Laura Medina Rodriguez, Andrew M. Lowy, Erkut Borazanci, Ignacio Garrido-Laguna, Wells A. Messersmith, Kian-Huat Lim, Rocio Garcia-Carbonero, Manuel Hidalgo
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da0734ac3a6c2b301da9b99749ffbf3
https://doi.org/10.1158/2767-9764.22545084.v1
https://doi.org/10.1158/2767-9764.22545084.v1
Autor:
Teresa Macarulla, Kenneth Kern, Yanke Yu, Jean-François Martini, Meggan Tammaro, Xin Huang, Joseph E. Grossman, David J. Shields, Marcos Malumbres, Beatriz Salvador-Barbero, Daniel Laheru, Laura Medina Rodriguez, Andrew M. Lowy, Erkut Borazanci, Ignacio Garrido-Laguna, Wells A. Messersmith, Kian-Huat Lim, Rocio Garcia-Carbonero, Manuel Hidalgo
Supplementary Table S3 from A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db40870c85b7c804573ee162c6ddf05
https://doi.org/10.1158/2767-9764.22545072.v1
https://doi.org/10.1158/2767-9764.22545072.v1
Autor:
Manuel Hidalgo, Senthil K. Muthuswamy, Mark Callery, Tara S. Kent, Martin Smith, Tyler M. Berzin, Douglas Pleskow, Mandeep S. Sawhney, Robert Besaw, Roger B. Davis, Christine Lim, Supraja Narasimhan, Catherine Conahan, Mary Linton B. Peters, Benjamin Schlechter, Andrea J. Bullock, Bruno Bockorny, Jonah Cohen, Leo L. Tsai, Raul S. Gonzalez, Sofia Perea, Dipikaa Akshinthala, Ling Huang, Lakshmi Muthuswamy, Joseph E. Grossman
Supplementary Data from Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1260fc09a1c2717a2c1423956de7284d
https://doi.org/10.1158/1078-0432.22484078
https://doi.org/10.1158/1078-0432.22484078
Autor:
Manuel Hidalgo, Senthil K. Muthuswamy, Mark Callery, Tara S. Kent, Martin Smith, Tyler M. Berzin, Douglas Pleskow, Mandeep S. Sawhney, Robert Besaw, Roger B. Davis, Christine Lim, Supraja Narasimhan, Catherine Conahan, Mary Linton B. Peters, Benjamin Schlechter, Andrea J. Bullock, Bruno Bockorny, Jonah Cohen, Leo L. Tsai, Raul S. Gonzalez, Sofia Perea, Dipikaa Akshinthala, Ling Huang, Lakshmi Muthuswamy, Joseph E. Grossman
Purpose:Pancreatic ductal adenocarcinoma (PDAC) remains a significant health issue. For most patients, there are no options for targeted therapy, and existing treatments are limited by toxicity. The HOPE trial (Harnessing Organoids for PErsonalized T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2c3cab84e98173ebbc1888ec47fd08
https://doi.org/10.1158/1078-0432.c.6531320
https://doi.org/10.1158/1078-0432.c.6531320
Autor:
Bruno Bockorny, Lakshmi Muthuswamy, Ling Huang, Marco Hadisurya, Christine Maria Lim, Leo L. Tsai, Ritu R. Gill, Jesse L. Wei, Andrea J. Bullock, Joseph E. Grossman, Robert J. Besaw, Supraja Narasimhan, W. Andy Tao, Sofia Perea, Mandeep S. Sawhney, Steven D. Freedman, Manuel Hidalgo, Anton Iliuk, Senthil K. Muthuswamy
Publikováno v:
medRxiv
Pancreatic cancer has the worst prognosis of all common tumors. Earlier cancer diagnosis could increase survival rates and better assessment of metastatic disease could improve patient care. As such, there is an urgent need to develop biomarkers to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be9a56795ec8bd6bfdbbb0483831de1
https://doi.org/10.1101/2023.03.13.23287216
https://doi.org/10.1101/2023.03.13.23287216
Autor:
Lakshmi Muthuswamy, Ling Huang, Raul S. Gonzalez, Jonah Cohen, Senthil K. Muthuswamy, Catherine Conahan, Supraja Narasimhan, Tyler M. Berzin, Mandeep S. Sawhney, Andrea J. Bullock, Mary Linton B. Peters, Sofia Perea, Roger B. Davis, Benjamin Schlechter, Bruno Bockorny, Dipikaa Akshinthala, Robert J. Besaw, Mark P. Callery, Douglas K. Pleskow, Leo L. Tsai, Martin P. Smith, Christine Maria Lim, Manuel Hidalgo, Tara S. Kent, Joseph E. Grossman
Publikováno v:
Clin Cancer Res
Purpose: Pancreatic ductal adenocarcinoma (PDAC) remains a significant health issue. For most patients, there are no options for targeted therapy, and existing treatments are limited by toxicity. The HOPE trial (Harnessing Organoids for PErsonalized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a528f7d154a6854e7926499da596a9af
https://doi.org/10.1158/1078-0432.ccr-20-4116
https://doi.org/10.1158/1078-0432.ccr-20-4116