Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Joseph E Dinchuk"'
Autor:
Ricardo A Garcia, Mujing Yan, Debra Search, Rongan Zhang, Nancy L Carson, Carol S Ryan, Constance Smith-Monroy, Joanna Zheng, Jian Chen, Yan Kong, Huaping Tang, Samuel E Hellings, Judith Wardwell-Swanson, Joseph E Dinchuk, George C Psaltis, David A Gordon, Peter W Glunz, Peter S Gargalovic
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111385 (2014)
BACKGROUND: P2Y(6), a purinergic receptor for UDP, is enriched in atherosclerotic lesions and is implicated in pro-inflammatory responses of key vascular cell types and macrophages. Evidence for its involvement in atherogenesis, however, has been lac
Externí odkaz:
https://doaj.org/article/226e843b35fe4bc7b87247e99442f01e
Publikováno v:
Freeze-Fracture Studies of Membranes ISBN: 9781351072151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11400f48193c57919d9a3e3a32d72778
https://doi.org/10.1201/9781351072151-3
https://doi.org/10.1201/9781351072151-3
Autor:
Aaron Balog, Mark E. Salvati, Paul Levesque, Stephanie S. Powlin, Mary T. Obermeier, Marco M. Gottardis, Joseph E. Dinchuk, Ricardo M. Attar, Hong Shi, Bruce D. Car, Joseph C. Arezzo, William R. Foster, Jinping Gan
Publikováno v:
The Prostate. 71:480-488
BACKGROUND Androgen receptor (AR) antagonists are part of the standard of care for prostate cancer. Despite the almost inevitable development of resistance in prostate tumors to AR antagonists, no new AR antagonists have been approved for over a deca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec79d3d537544418a848d6b5508c8c9a
https://doi.org/10.1002/pros.21263
https://doi.org/10.1002/pros.21263
Autor:
Marco M. Gottardis, Karen A. Reeves, Ricardo M. Attar, Fanny Myers, Joan M. Carboni, Fei Huang, Xiadi Zhou, Joseph E. Dinchuk, Jeanne Wang, Glenn H. Cantor, Carolyn Cao
Publikováno v:
Endocrinology. 151:4123-4132
The biology of IGF-IR/IR signaling was studied in normal mouse embryonic fibroblasts (MEFs) that were either wild type (wt), heterozygous (het), or null for the IGF-IR. The ability of IGF-I, IGF-II, or insulin to stimulate serum-starved MEFs was char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358e7ac14032e092871c255cbc737bb0
https://doi.org/10.1210/en.2010-0032
https://doi.org/10.1210/en.2010-0032
Autor:
Alejandro Peralta Soler, George C. Prendergast, James B. DuHadaway, Preston S. Donover, Minzhou Huang, Yan Wang, Janette Boulden, Joseph E. Dinchuk, Alexander J. Muller, Arivudainambi Ramalingam, Lois M. McNally, Erika Sutanto-Ward, Melinda K. Duncan
Publikováno v:
Cancer Research. 68:1683-1690
Bin3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins, which includes the BAR, PCH/F-BAR, and I-BAR adapter proteins implicated in signal transduction and vesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b4151ce89c663b271ad7620c32cea5
https://doi.org/10.1158/0008-5472.can-07-6072
https://doi.org/10.1158/0008-5472.can-07-6072
Autor:
Debra Search, Huaping Tang, Mujing Yan, Ricardo Garcia, Nancy L. Carson, Joseph E. Dinchuk, Constance Smith-Monroy, Yan Kong, Rongan Zhang, David A. Gordon, Jian Chen, Carol S. Ryan, Peter S. Gargalovic, George C. Psaltis, Judith Wardwell-Swanson, Joanna Zheng, Samuel Hellings, Peter W. Glunz
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111385 (2014)
PLoS ONE
PLoS ONE
BACKGROUND: P2Y(6), a purinergic receptor for UDP, is enriched in atherosclerotic lesions and is implicated in pro-inflammatory responses of key vascular cell types and macrophages. Evidence for its involvement in atherogenesis, however, has been lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11518aa5c4d880ccca2945de0b9894e
http://europepmc.org/articles/PMC4216081?pdf=render
http://europepmc.org/articles/PMC4216081?pdf=render
Autor:
Robert Langenbach, James M. Trzaskos, Hyunjung Jade Lim, Joseph E. Dinchuk, Sudhansu K. Dey, Bibhash C. Paria, Sanjoy K. Das
Publikováno v:
Cell. 91(2):197-208
Cyclooxygenase (COX) is the rate-limiting enzyme in the synthesis of prostaglandins (PGs) and exists in two isoforms, COX-1 and COX-2. In spite of long-standing speculation, definitive roles of PGs in various events of early pregnancy remain elusive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036c58803e437635f111932c9c63b64f
Autor:
Richard J. Focht, Bruce D. Car, Nancy R. Contel, Joseph E. Dinchuk, Stewart A. Gorry, Jennifer J. Johnston, Bruce D. Jaffee, James M. Trzaskos, Robert Collins, Vicki M. Eng, Maryanne B. Covington, P. M. Czerniak
Publikováno v:
Nature. 378:406-409
Prostaglandins have wide-ranging effects in the body and are thought to be important mediators of inflammation. Cyclooxygenase (COX) plays a key regulatory role in prostaglandin synthesis, and occurs in both constitutive (COX-1) and inducible (COX-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136e8be3ea96b519b03312c38908ce01
https://doi.org/10.1038/378406a0
https://doi.org/10.1038/378406a0
Autor:
Dana O. Wirak, Joseph E. Dinchuk, Delf Schmidt, John Hart, Genevieve Gonzalez, Guenther Karmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1255:301-310
Cholesteryl ester transfer protein (CETP) facilitates the transfer of reciprocal exchange of neutral lipids between lipoproteins. To better understand the function of CETP and its role in atherogenic pathways, transgenic mice which express human CETP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee795deff0f786264555712320c5a0a1
https://doi.org/10.1016/0005-2760(94)00246-u
https://doi.org/10.1016/0005-2760(94)00246-u
Autor:
Asis Palazon, Ivan Martinez-Forero, Juan Dubrot, Alfredo Martínez, Alfonso Luque, Iván Peñuelas, Alvaro Teijeira, Laura Ochoa-Callejero, Ignacio Melero, Ana Rouzaut, Carmen Roncal, M. Carmen Ochoa, Jose Luis Perez-Gracia, Sandra Hervas-Stubbs, Maria Jure-Kunkel, Joseph E. Dinchuk, Aizea Morales-Kastresana
Agonist monoclonal antibodies (mAb) to the immune costimulatory molecule CD137, also known as 4-1BB, are presently in clinical trials for cancer treatment on the basis of their costimulatory effects on primed T cells and perhaps other cells of the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92541965666a6ca63760b74319224e3a
https://hdl.handle.net/10171/20317
https://hdl.handle.net/10171/20317