Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Joseph Dosch"'
Autor:
Stephen P. Cavnar, Andrew D. Rickelmann, Kaille F. Meguiar, Annie Xiao, Joseph Dosch, Brendan M. Leung, Sasha Cai Lesher-Perez, Shashank Chitta, Kathryn E. Luker, Shuichi Takayama, Gary D. Luker
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 8, Pp 625-633 (2015)
Patients with many types of malignancy commonly harbor quiescent disseminated tumor cells in bone marrow. These cells frequently resist chemotherapy and may persist for years before proliferating as recurrent metastases. To test for compounds that el
Externí odkaz:
https://doaj.org/article/e3104e71696844408a7a2b88966b2d55
Autor:
Theodore H. Welling, Kathryn E. Luker, Robert E. Hollingsworth, Ronald Herbst, Judith S. Sebolt-Leopold, Jonathan Rios-Doria, Eric R. Fearon, Elizabeth Ziemke, Matt Flynn, Joseph Dosch, Suneetha Thomas, Elaine M. Hurt, Karin M. Hardiman, Shanshan Wan
Publikováno v:
Oncotarget
// Joseph Dosch 1, * , Elizabeth Ziemke 1, * , Shanshan Wan 2 , Kathryn Luker 1 , Theodore Welling 2 , Karin Hardiman 2 , Eric Fearon 3 , Suneetha Thomas 4 , Matthew Flynn 4 , Jonathan Rios-Doria 4 , Robert Hollingsworth 4 , Ronald Herbst 4 , Elaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6965405e12907d677a15f83cd444fa
https://doi.org/10.18632/oncotarget.17780
https://doi.org/10.18632/oncotarget.17780
Autor:
Brendan M. Leung, Kathryn E. Luker, Shashank Chitta, Stephen P. Cavnar, Andrew D. Rickelmann, Kaille F. Meguiar, Annie Xiao, Shuichi Takayama, Gary D. Luker, Sasha Cai Lesher-Perez, Joseph Dosch
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 8, Pp 625-633 (2015)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 8, Pp 625-633 (2015)
Patients with many types of malignancy commonly harbor quiescent disseminated tumor cells in bone marrow. These cells frequently resist chemotherapy and may persist for years before proliferating as recurrent metastases. To test for compounds that el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a50721a1be76f1fad3cefc573d14a98
https://doi.org/10.1016/j.neo.2015.08.001
https://doi.org/10.1016/j.neo.2015.08.001
Publikováno v:
Pancreatology. 10:151-157
While several aberrant signaling pathways have been attributed to the formation and progression of pancreatic cancer, there is mounting evidence for the increased role of the Hedgehog (Hh) pathway in multiple aspects of pancreatic tumor development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44b3cee038daa4f232d11e7d2220f82
https://doi.org/10.1159/000225923
https://doi.org/10.1159/000225923
Publikováno v:
Chemical Reviews. 109:3200-3208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626c903353e92dfdaa25052af654d9c0
https://doi.org/10.1021/cr9000397
https://doi.org/10.1021/cr9000397
Autor:
Amanda C. Stacer, Brian D. Ross, Joseph Fenner, Joseph Dosch, Gary D. Luker, Hanxiao Wang, Alnawaz Rehemtulla, Kathryn E. Luker, Anna Salomonnson
Publikováno v:
Molecular Imaging, Vol 14 (2015)
Tumor-initiating cells, also designated as cancer stem cells, are proposed to constitute a subpopulation of malignant cells central to tumorigenesis, metastasis, and treatment resistance. We analyzed the activity of the proteasome, the primary organe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7f2aa20edcf4c00176aa439a631ccb
https://doaj.org/article/150fc92789d444349a002a256c115e9d
https://doaj.org/article/150fc92789d444349a002a256c115e9d
Autor:
Chandan Kumar-Sinha, Katerina Chekhovskiy, Hongtao Yu, Katrina Schinske-Sebolt, Shyam Nyati, Dipankar Ray, Nauman Chaudhry, Sooryanarayana Varambally, Nils G. Walter, Mukesh K. Nyati, Areeb Chator, Marcian E. Van Dort, Sethuramasundaram Pitchiaya, Alnawaz Rehemtulla, Brian D. Ross, Joseph Dosch
Publikováno v:
Neoplasia (New York, N.Y.)
Transforming growth factor-β (TGF-β) signaling regulates cell proliferation and differentiation, which contributes to development and disease. Upon binding TGF-β, the type I receptor (TGFBRI) binds TGFBRII, leading to the activation of the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc46213aff1cbf073feebbdb119d2e01
https://doi.org/10.1126/scisignal.2005379
https://doi.org/10.1126/scisignal.2005379
Autor:
Elizabeth Ziemke, Alnawaz Rehemtulla, Amrith Shettigar, Joseph Dosch, Judith S. Sebolt-Leopold
Publikováno v:
Cancer research. 75(21)
Survival rates associated with pancreatic cancer remain dismal despite advancements in detection and experimental treatment strategies. Genetically engineered mouse models of pancreatic tumorigenesis have gained considerable attention based on their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437ec622e16dabe1dd5eeb6e0e138e1a
https://pubmed.ncbi.nlm.nih.gov/26359451
https://pubmed.ncbi.nlm.nih.gov/26359451
Autor:
Diane M. Simeone, Chenwei Li, Marina Pasca di Magliano, Bedabrata Sarkar, Mark Hynes, Joseph Dosch, Jing Jiang Wu, Theodore H. Welling
Publikováno v:
Gastroenterology. 141(6)
Background & Aims Growth of many different tumor types requires a population of self-renewing cancer stem cells (CSCs). c-Met is a marker of normal mouse pancreatic stem and progenitor cells; we investigated whether it is also a marker of human pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d80176969806134f00e9b5317edd4a
https://pubmed.ncbi.nlm.nih.gov/21864475
https://pubmed.ncbi.nlm.nih.gov/21864475
Publikováno v:
Stem Cells and Cancer ISBN: 9781603279321
Pancreatic cancer is a devastating disease that usually presents at a late stage that is not amenable to curative treatments. It is notoriously resistant to chemotherapy and radiation, and it is clear that new treatment strategies are needed to posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9785908106d6d42b69515ac0d0e19383
https://doi.org/10.1007/978-1-60327-933-8_15
https://doi.org/10.1007/978-1-60327-933-8_15
