Vitamin D3 Supplementation Increases Spine Bone Mineral Density in Adolescents and Young Adults With Human Immunodeficiency Virus Infection Being Treated With Tenofovir Disoproxil Fumarate: A Randomized, Placebo-Controlled Trial

Autor: Rohan Hazra, John H. Stroger, Maria Campos, Patricia M. Flynn, Craig M. Wilson, Brandy Rutledge, Dan Reirden, Julian Dormitzer, Renata Sanders, Marvin Belzer, Lisa Henry-Reid, Zulma Eysallenne, Joanna Dobroszycki, Donna Maturo, Lourdes Angeli Nieves, Allison Bearden, Steve Douglas, Roger A. Fielding, Sue Ellen Abdalian, Andrew Wiznia, Midnela Acevedo, James Homans, Charles B. Stephensen, Leslie Kozina, Donna Futterman, Jane Head, Larry D'Angelo, Jacobo Abadi, Mary Tanney, Mary E. Paul, Marlene Burey, Eva Operskalski, Bill G. Kapogiannis, Charnell Cromer, Susie Sanchez, Kelly Bojan, Peter L. Havens, Liz Secord, Carrie Chambers, Elizabeth Enriquez-Bruce, Kenneth H. Mayer, Michael G. Rosenberg, Cynthia G. Pan, Aditya Guar, Justin J. Wheeler, Leslie R. Woodhouse, Joseph Domek, William A. Meyer, Angulique Outlaw, Thuy Anderson, Kathleen Mulligan, Georgine Price, Diane Tucker, Mary Dillard, Larry Friedman, Erik Gertz, Connie Trexler, Andrea Kovacs, Patricia Emmanuel, Diane M. Straub, Alyne Baker, Gertrud U. Schuster, Marta D. Van Loan, Miguel Angel Martinez, Allison L. Agwu, Nicolas Rosario, Kavya Vellala, Catherine M. Gordon, Tammy L. Freytag, D. Robert Harris, Ana Puga

Publikováno v: Clinical Infectious Diseases. 66:220-228

Background Tenofovir disoproxil fumarate (TDF) decreases bone mineral density (BMD). We hypothesized that vitamin D3 (VITD3) would increase BMD in youth receiving TDF. Methods This was a randomized, double-blind, placebo-controlled trial of directly

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https://doi.org/10.1093/cid/cix753