Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joseph DeYoung"'
Autor:
James R. Hilser, Jaana A. Hartiala, Intira Sripras, Naoko Kono, Zhiheng Cai, Roksana Karim, Joseph Deyoung, Wendy J. Mack, Howard N. Hodis, Hooman Allayee
Publikováno v:
Clinical Epigenetics. 14
BackgroundCardiovascular disease (CVD) remains the leading cause of death among postmenopausal women but standard primary prevention strategies in women are not as effective as in men. By comparison, the Early versus Late Intervention Trial with Estr
Autor:
Caesar Z. Li, Amin Haghani, Joseph DeYoung, Roger P. Woods, Julie A. Mattison, Andrew W. Rao, Oi-Wa Choi, Xinmin Li, Adriana Arneson, Jason Ernst, Joseph A. Zoller, Matthew J. Jorgensen, Giovanni Coppola, Kylie Kavanagh, Anna J. Jasinska, Steve Horvath, Nelson B. Freimer, Kevin Wojta
Publikováno v:
GeroScience. 44(2)
DNA methylation-based biomarkers of aging have been developed for many mammals but not yet for the vervet monkey (Chlorocebus sabaeus), which is a valuable non-human primate model for biomedical studies. We generated novel DNA methylation data from v
Autor:
Caesar Z. Li, Amin Haghani, Todd R. Robeck, Diego Villar, Ake T. Lu, Joshua Zhang, Chris G. Faulkes, Ha Vu, Julia Ablaeva, Danielle M. Adams, Reza Ardehali, Adriana Arneson, C. Scott Baker, Katherine Belov, Daniel T. Blumstein, Eleanor K. Bors, Charles E. Breeze, Robert T. Brooke, Janine L. Brown, Alex Caulton, Julie M. Cavin, Ioulia Chatzistamou, Hao Chen, Priscila Chiavellini, Oi-Wa Choi, Shannon Clarke, Joseph DeYoung, Candice K. Emmons, Stephan Emmrich, Zhe Fei, Steven H. Ferguson, Carrie J. Finno, Jennifer E. Flower, Jean-Michel Gaillard, Eva Garde, Vadim N. Gladyshev, Rodolfo G. Goya, M. Bradley Hanson, Martin Haulena, Kelsey Herrick, Andrew N. Hogan, Carolyn J. Hogg, Timothy A. Hore, Anna J. Jasinska, Gareth Jones, Eve Jourdain, Olga Kashpur, Harold Katcher, Etsuko Katsumata, Vimala Kaza, Hippokratis Kiaris, Michael S. Kobor, Pawel Kordowitzki, William R. Koski, Brenda Larison, Sang-Goo Lee, Marianne Lehmann, Jean-Francois Lemaitre, Andrew J. Levine, Cun Li, Xinmin Li, David TS Lin, Dana M. Lindemann, Nicholas Macoretta, Dewey Maddox, Craig O. Matkin, Julie A. Mattison, June Mergl, Jennifer J. Meudt, Gisele A. Montano, Khyobeni Mozhui, Asieh Naderi, Martina Nagy, Pritika Narayan, Peter W. Nathanielsz, Ngoc B. Nguyen, Christof Niehrs, Duncan T Odom, Alexander G. Ophir, Elaine A. Ostrander, Perrie O'Tierney Ginn, Kim M. Parsons, Kimberly C. Paul, Matteo Pellegrini, Gabriela M. Pinho, Jocelyn Plassais, Natalia A. Prado, Benjamin Rey, Beate R. Ritz, Jooke Robbins, Magdalena Rodriguez, Jennifer Russell, Elena Rydkina, Lindsay L. Sailer, Adam B. Salmon, Akshay Sanghavi, Kyle M. Schachtschneider, Dennis Schmitt, Lars Schomacher, Lawrence B. Schook, Karen E. Sears, Ashley W. Seifert, Anastasia V. Shindyapina, Kavita Singh, Ishani Sinha, Russel G. Snell, Elham Soltanmohammadi, Matthew L. Spangler, Maria Spriggs, Karen J. Steinman, Victoria J. Sugrue, Balazs Szladovits, Masaki Takasugi, Emma C. Teeling, Bill Van Bonn, Sonja C. Vernes, Harry V. Vinters, Mary C. Wallingford, Nan Wang, Gerald S. Wilkinson, Robert W. Williams, X. William Yang, Brent G. Young, Bohan Zhang, Zhihui Zhang, Peng Zhao, Yang Zhao, Wanding Zhou, Joseph A. Zoller, Jason Ernst, Andrei Seluanov, Ken Raj, Vera Gorbunova, Steve Horvath
Maximum lifespan of a species is the oldest that individuals can survive, reflecting the genetic limit of longevity in an ideal environment. Here we report methylation-based models that accurately predict maximum lifespan (r=0.89), gestational time (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fee697f5dd92102b3316fdd9b4d13a89
https://doi.org/10.1101/2021.05.16.444078
https://doi.org/10.1101/2021.05.16.444078
Autor:
Andrew W. Rao, Adriana Arneson, Kevin Wojta, Caesar Z. Li, Joseph A. Zoller, Kylie Kavanagh, Nelson B. Freimer, Joseph DeYoung, Anna J. Jasinska, Matthew J. Jorgensen, Giovanni Coppola, Steve Horvath, Amin Haghani, Roger P. Woods, Oi-Wa Choi, Xinmin Li, Julie A. Mattison, Jason Ernst
DNA methylation-based biomarkers of aging have been developed for many mammals but not yet for the vervet monkey (Chlorocebus sabaeus), which is a valuable non-human primate model for biomedical studies. We generated novel DNA methylation data from v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a4cc5670a9a709d92db0738a05e9818
https://doi.org/10.1101/2020.09.09.289801
https://doi.org/10.1101/2020.09.09.289801
Autor:
Matthew J. Jorgensen, Giovanni Coppola, Ken Dewar, George M. Weinstock, Emily S. W. Wong, Joseph DeYoung, Chiara Sabatti, Scott C. Fears, Wesley C. Warren, David J. Jentsch, Lynn A. Fairbanks, Richard K. Wilson, Christine B. Peterson, Nelson B. Freimer, Anna J. Jasinska, Eleazar Eskin, Jay R. Kaplan, Allison E. Furterer, John Blangero, Thomas D. Dyer, Ivette Zelaya, Diego Villar, Vasily Ramensky, Yu S. Huang, Oi Wa Choi, Rita M. Cantor, Hannes Svardal, Roger P. Woods, Marina Bogomolov, Christopher A. Schmitt, Bronwen Aken, Yoav Benjamini, Rishi Nag, Paul Flicek
Publikováno v:
Nature genetics
Nature genetics, vol 49, iss 12
Nature genetics, vol 49, iss 12
By analyzing multi-tissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalogue of expression quantitative trait loci (eQTLs) in a non-h
Autor:
Teus H. Kappen, Jacobine E. Buizer-Voskamp, Eske M. Derks, K. van Eijk, M Neeleman, Jurjen J. Luykx, M van Amerongen, Jae Hoon Sul, Eric Strengman, Eskin E, Peter J M Keijzers, J. van Setten, Eef G.W.M. Lentjes, L Mentink, E P A van Dongen, S de Jong, P Borgdorff, Peter Bruins, Steven C. Bakker, Ake Tzu-Hui Lu, Rita M. Cantor, Joseph DeYoung, Roel A. Ophoff, René S. Kahn
Publikováno v:
Molecular psychiatry, 19(2), 228-234. Nature Publishing Group
Studying genetic determinants of intermediate phenotypes is a powerful tool to increase our understanding of genotype-phenotype correlations. Metabolic traits pertinent to the central nervous system (CNS) constitute a potentially informative target f
Autor:
Oi-Wa Choi, J. David Jentsch, Michelle K. Lin, Lynn A. Fairbanks, George M. Weinstock, Jessica Wasserscheid, Sit-yee Kong, Olivera Grujic, Wesley C. Warren, Richard K. Wilson, Trudy R. Turner, Yoon Jung, Ken Dewar, Rita M. Cantor, Joseph DeYoung, Nelson B. Freimer, Anna J. Jasinska, Mathew J. Jorgensen
Publikováno v:
Human Molecular Genetics. 21:3307-3316
Non-human primates provide genetic model systems biologically intermediate between humans and other mammalian model organisms. Populations of Caribbean vervet monkeys (Chlorocebus aethiops sabaeus) are genetically homogeneous and large enough to perm
Autor:
Anil P.S. Ori, Roel A. Ophoff, Joseph DeYoung, Teus H. Kappen, Nanda M. Verhoeven-Duif, Rita M. Cantor, Jacobine E. Buizer-Voskamp, J M den Heijer, Jae Hoon Sul, Eleazar Eskin, Wouter F. Visser, E P A van Dongen, P Borgdorff, E Pariama, Steven C. Bakker, Eric Strengman, Jurjen J. Luykx, Marco P. Boks, Peter Bruins, Jacob A. S. Vorstman, T. J. de Koning, René S. Kahn
Publikováno v:
Molecular Psychiatry, 20(12), 1557-1564. Nature Publishing Group
Molecular Psychiatry, 20(12), 1557. Nature Publishing Group
Molecular Psychiatry, 20(12), 1557. Nature Publishing Group
The N-methyl-d-aspartate receptor (NMDAR) coagonists glycine, d-serine and l-proline play crucial roles in NMDAR-dependent neurotransmission and are associated with a range of neuropsychiatric disorders. We conducted the first genome-wide association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3c309201c9573ece928c818977a497
https://research.rug.nl/en/publications/987f4814-48ca-4343-a25e-97735306d5ae
https://research.rug.nl/en/publications/987f4814-48ca-4343-a25e-97735306d5ae
Autor:
Anna J. Jasinska, Susan Service, Oi-wa Choi, Joseph DeYoung, Olivera Grujic, Sit-yee Kong, Matthew J. Jorgensen, Julia Bailey, Sherry Breidenthal, Lynn A. Fairbanks, Roger P. Woods, J. David Jentsch, Nelson B. Freimer
Publikováno v:
Human molecular genetics, vol 18, iss 22
Human Molecular Genetics
Human Molecular Genetics
Genome-wide gene expression studies may provide substantial insight into gene activities and biological pathways differing between tissues and individuals. We investigated such gene expression variation by analyzing expression profiles in brain tissu
Autor:
Joseph DeYoung, Rita M. Cantor, Tina Wang, Alexander Richards, Kim A. Staats, Anil P.S. Ori, Loes M. Olde Loohuis, Ganna Leonenko, James T.R. Walters, Jacob A. S. Vorstman, Roel A. Ophoff
Publikováno v:
Nature communications, vol 6, iss 1
Nature Communications [E], 6. Nature Publishing Group
Nature Communications
Nature Communications [E], 6. Nature Publishing Group
Nature Communications
Schizophrenia is a common complex disorder with polygenic inheritance. Here we show that by using an approach that compares the individual loads of rare variants in 1,042 schizophrenia cases and 961 controls, schizophrenia cases carry an increased bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d619b7eeb250a448bb557fa1a20ab2e3
https://lirias.kuleuven.be/handle/123456789/514360
https://lirias.kuleuven.be/handle/123456789/514360