Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph DeVito"'
Autor:
Ishan Taneja, Gregory L. Damhorst, Carlos Lopez‐Espina, Sihai Dave Zhao, Ruoqing Zhu, Shah Khan, Karen White, James Kumar, Andrew Vincent, Leon Yeh, Shirin Majdizadeh, William Weir, Scott Isbell, James Skinner, Manubolo Devanand, Syed Azharuddin, Rajamurugan Meenakshisundaram, Riddhi Upadhyay, Anwaruddin Syed, Thomas Bauman, Joseph Devito, Charles Heinzmann, Gregory Podolej, Lanxin Shen, Sanjay Sharma Timilsina, Lucas Quinlan, Setareh Manafirasi, Enrique Valera, Bobby Reddy Jr., Rashid Bashir
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1578-1589 (2021)
Abstract Sepsis is a major cause of mortality among hospitalized patients worldwide. Shorter time to administration of broad‐spectrum antibiotics is associated with improved outcomes, but early recognition of sepsis remains a major challenge. In a
Externí odkaz:
https://doaj.org/article/b73452aad80f45de929243cd1eb9c8ba
Autor:
Riddhi Upadhyay, Leon Yeh, Charles Heinzmann, Manubolo Devanand, Sanjay Sharma Timilsina, Bobby Reddy, Rajamurugan Meenakshisundaram, Ruoqing Zhu, Gregory Podolej, Lanxin Shen, Shirin Majdizadeh, Syed Azharuddin, William Bradley Weir, Ishan Taneja, James Skinner, Karen White, Sihai Dave Zhao, Gregory L. Damhorst, Shah Khan, Thomas Bauman, Anwaruddin Syed, James Kumar, Enrique Valera, Andrew Vincent, Lucas Quinlan, Setareh Manafirasi, Rashid Bashir, Joseph Devito, Carlos Lopez-Espina, Scott Isbell
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1578-1589 (2021)
Clinical and Translational Science
Clinical and Translational Science
Sepsis is a major cause of mortality among hospitalized patients worldwide. Shorter time to administration of broad‐spectrum antibiotics is associated with improved outcomes, but early recognition of sepsis remains a major challenge. In a two‐cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4004b5a0035f76a984c192fc8df32e10
https://doaj.org/article/b73452aad80f45de929243cd1eb9c8ba
https://doaj.org/article/b73452aad80f45de929243cd1eb9c8ba
Publikováno v:
Clinical Research and Regulatory Affairs. 23:97-123
A pre-approval inspection (PAI) is defined as a visit by one or more health agency investigators to review the adequacy and accuracy of the information provided in a regulatory submission seeking registration of a drug product to introduce into comme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d802617813e1b351928fecd3825cd7c9
https://doi.org/10.1080/10601330600734332
https://doi.org/10.1080/10601330600734332
Autor:
Asis Das, Evangeline Peralta, Joseph DeVito, Pramatha Bhattacharya, Balaram Ghosh, Elizabeth Grzadzielska
Publikováno v:
Journal of Molecular Biology. 222:59-66
Transcription of the ribosomal RNA operons (rrn) in Escherichia coli is subject to an antitermination mechanism whereby RNA polymerase is modified to a termination-resistant form during transit through the rrn leader region. This antitermination mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a40f93dc92893481812480fd2611028
https://doi.org/10.1016/0022-2836(91)90737-q
https://doi.org/10.1016/0022-2836(91)90737-q
Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.
Title from electronic title page (viewed Feb. 26, 2009). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Curriculum in Toxicology."
Title from electronic title page (viewed Feb. 26, 2009). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Curriculum in Toxicology."
Externí odkaz:
http://dc.lib.unc.edu/u?/etd,2168
Autor:
Michael Tyrkus, Maarten C. Bosland, Jyotsna Sundar, Joseph Devito, Andre Kajdacsy-Balla, Gnanasekar Munirathinam
Publikováno v:
Cancer Research. 73:4381-4381
Prostate carcinoma (PCa) is one of the most frequently diagnosed cancers in US men causing an estimated 30,000 deaths annually. The primary cause for deaths related to PCa is the development of metastases. Although these patients initially respond to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac84ab15f869219c4630da602cab9fd
https://doi.org/10.1158/1538-7445.am2013-4381
https://doi.org/10.1158/1538-7445.am2013-4381
Autor:
Joseph DeVito, Donald L. Court, William Whalen, William A. Rees, Peter H. von Hippel, Jaime Garcia Mena, Robin Crossley, Nina Costantino, Balaram Ghosh, Krystyna Wolska, Samit Chattopadhyay, Marie J. Mazzulla, Asis Das, Mahadeb Pal, Amanda S. Altieri, R. Andrew Byrd
Publisher Summary This chapter discusses the components of multiprotein-RNA complex that controls transcription elongation in Escherichia Coli phage λ. Studies of bacteriophage A led to the discovery of several basic mechanisms of transcriptional re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8cc7f7d963c9feac99e19de95b8da4
https://doi.org/10.1016/s0076-6879(96)74032-6
https://doi.org/10.1016/s0076-6879(96)74032-6
Transcription of downstream genes in the early operons of phage lambda requires a promoter-proximal element known as nut. This site acts in cis in the form of RNA to assemble a transcription antitermination complex which is composed of lambda N prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a48bfb3920f29f16f05deee90db065
https://europepmc.org/articles/PMC42102/
https://europepmc.org/articles/PMC42102/
Autor:
Joseph DeVito, Asis Das
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(18)
During transcription of phage lambda early operons, the N gene product alters host RNA polymerase (RNAP) so that transcription proceeds through multiple stop signals. Here, we reproduce the essence of N activity with purified components in synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27a1fca77107270c5215c443718813c
https://pubmed.ncbi.nlm.nih.gov/7521531
https://pubmed.ncbi.nlm.nih.gov/7521531
Publikováno v:
Emerging Targets in Antibacterial and Antifungal Chemotherapy ISBN: 9781461364405
Transcription, the synthesis of RNA from DNA, is the first step in gene expression. It is a multistep biochemical process. RNA polymerase, the enzyme that catalyzes transcription, locates and binds a specific promoter sequence on the template DNA, un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfcfbed1dbbff00c303683ebc5964888
https://doi.org/10.1007/978-1-4615-3274-3_4
https://doi.org/10.1007/978-1-4615-3274-3_4