Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Joseph DeSimone"'
Autor:
Robert Molokie, Donald Lavelle, Michel Gowhari, Michael Pacini, Lani Krauz, Johara Hassan, Vinzon Ibanez, Maria A Ruiz, Kwok Peng Ng, Philip Woost, Tomas Radivoyevitch, Daisy Pacelli, Sherry Fada, Matthew Rump, Matthew Hsieh, John F Tisdale, James Jacobberger, Mitch Phelps, James Douglas Engel, Santhosh Saraf, Lewis L Hsu, Victor Gordeuk, Joseph DeSimone, Yogen Saunthararajah
Publikováno v:
PLoS Medicine, Vol 14, Iss 9, p e1002382 (2017)
BACKGROUND:Sickle cell disease (SCD), a congenital hemolytic anemia that exacts terrible global morbidity and mortality, is driven by polymerization of mutated sickle hemoglobin (HbS) in red blood cells (RBCs). Fetal hemoglobin (HbF) interferes with
Externí odkaz:
https://doaj.org/article/c7733c856c0b41248e7cccfad4c6af2d
Autor:
Stefan W Metz, Shaomin Tian, Gabriel Hoekstra, Xianwen Yi, Michelle Stone, Katie Horvath, Michael J Miley, Joseph DeSimone, Chris J Luft, Aravinda M de Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005071 (2016)
Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over 120 countries, causing over 350 million infections per year. Dengue vaccine development is challenging because of the need to induce
Externí odkaz:
https://doaj.org/article/185619cc0aa746ac9030670c9a9e6064
Autor:
Angela Rivers, Kestis Vaitkus, Vinzon Ibanez, Maria Armila Ruiz, Ramasamy Jagadeeswaran, Yogen Saunthararajah, Shuaiying Cui, James D. Engel, Joseph DeSimone, Donald Lavelle
Publikováno v:
Haematologica, Vol 101, Iss 6 (2016)
Increased fetal hemoglobin levels lessen the severity of symptoms and increase the lifespan of patients with sickle cell disease. Hydroxyurea, the only drug currently approved for the treatment of sickle cell disease, is not effective in a large prop
Externí odkaz:
https://doaj.org/article/b268484467364ba99d899853ae8b0cd9
Autor:
Donald Lavelle, Kestutis Vaitkus, Maria Armila Ruiz, Vinzon Ibanez, Tatiana Kouznetsova, Yogen Saunthararajah, Nadim Mahmud, Joseph DeSimone
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36846 (2012)
This study was performed to investigate the hypothesis that the erythroid micro-environment plays a role in regulation of globin gene expression during adult erythroid differentiation. Adult baboon bone marrow and human cord blood CD34+ progenitors w
Externí odkaz:
https://doaj.org/article/391de4e825e4450f8ddf210e93828059
Publikováno v:
FACE. 3:313-318
Background/Purpose: In craniosynostosis, diagnostic imaging is crucial for identifying skull abnormalities, planning for surgical correction, and post-operative and follow-up evaluations. However, classifying postoperative corrected skull morphology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dcc6090948bb869d04a41b53d08fd22
https://doi.org/10.1177/27325016221102512
https://doi.org/10.1177/27325016221102512
Publikováno v:
Extended Abstracts of the 2023 CHI Conference on Human Factors in Computing Systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e608d476126a869f98559570213adb4
https://doi.org/10.1145/3544549.3585891
https://doi.org/10.1145/3544549.3585891
Autor:
Rebecca R. Soares, Charles Huang, Nick Boucher, Nitika Aggarwal, Rusirini Fernando, John Hinkle, Joseph DeSimone, Louis Cai, Samir N. Patel, David Xu, Ajay E. Kuriyan, Yoshihiro Yonekawa
Publikováno v:
Retina. 42:607-615
To characterize how community mobility patterns across the United States correlate with local changes in retina visits during the pandemic.Outpatient retina clinic visits were linked to population mobility by combining multiple public data sets, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a295846d78255bbc1d9e33859ba96fac
https://doi.org/10.1097/iae.0000000000003449
https://doi.org/10.1097/iae.0000000000003449
Autor:
C. Tilden Hagan, Cameron Bloomquist, Samuel Warner, Nicole M. Knape, Isaiah Kim, Hayley Foley, Kyle T. Wagner, Sue Mecham, Joseph DeSimone, Andrew Z. Wang
Publikováno v:
J Control Release
Surgery is an important treatment for cancer; however, local recurrence following macroscopically-complete resection is common and a significant cause of morbidity and mortality. Systemic chemotherapy is often employed as an adjuvant therapy to preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6f0de47a277288ab17b595d699af98
https://europepmc.org/articles/PMC9373975/
https://europepmc.org/articles/PMC9373975/
Autor:
C. Tilden Hagan, Cameron Bloomquist, Isaiah Kim, Nicole M. Knape, James D. Byrne, Litao Tu, Kyle Wagner, Sue Mecham, Joseph DeSimone, Andrew Z. Wang
Publikováno v:
Acta biomaterialia. 148
Brachytherapy, which is the placement of radioactive seeds directly into tissue such as the prostate, is an important curative treatment for prostate cancer. By delivering a high dose of radiation from within the prostate gland, brachytherapy is an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc3a2be2933bccde85686c530c7651d
https://pubmed.ncbi.nlm.nih.gov/35724920
https://pubmed.ncbi.nlm.nih.gov/35724920
Publikováno v:
Clinical Infection in Practice, Vol 12, Iss, Pp 100090-(2021)
A male patient in his thirties presented to the hospital with meningismus and altered mental status. Cerebrospinal fluid (CSF) analysis confirmed meningitis, but no microorganisms were identified. Head imaging (MRI) revealed multiple brain abscesses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dc2b325c4c3d2223751546eb010fa1
http://www.sciencedirect.com/science/article/pii/S2590170221000273
http://www.sciencedirect.com/science/article/pii/S2590170221000273