Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph DeAngelo"'
Autor:
Andreas Meier-Hellmann, Joseph DeAngelo, Harald Darius, Erwin Boehm, Christopher T. Privalle, Mervyn Singer, José A. Lorente, Ricard Ferrer, Gernot Marx, Jean Louis Vincent, J.M. Sirvent
Publikováno v:
Critical Care Medicine. 43:57-64
To compare the effectiveness and safety of the hemoglobin-based nitric oxide scavenger, pyridoxalated hemoglobin polyoxyethylene, against placebo in patients with vasopressor-dependent distributive shock.Multicenter, randomized, placebo-controlled, o
Autor:
Joseph DeAngelo, Matthew W. Chase, Chris Renzi, Thomas Phillips, Peter C. Michels, Marcella Powell, Stephanie Wagner
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 40:411-425
It has been half a century since investigators first began experimenting with adding ion exchange resins during the fermentation of microbial natural products. With the development of nonionic polymeric adsorbents in the 1970s, the application of in
Autor:
Raphael Nudelman, Kunal Merchant, Alfred Hausladen, Joseph DeAngelo, Jonathan S. Stamler, Wayne F. Beyer, Sung Oog Kim, Teresa Keng
Publikováno v:
Cell. 109(3):383-396
Redox regulation has been perceived as a simple on-off switch in proteins (corresponding to reduced and oxidized states). Using the transcription factor OxyR as a model, we have generated, in vitro, several stable, posttranslational modifications of
Autor:
Frank C. Schmalstieg, Lillian D. Traber, Daniel L. Traber, Katsumi Shimoda, Steve Lee, Joseph DeAngelo, Perenlei Enkhbaatar, Chris Privalle, Kazunori Murakami
Publikováno v:
Clinical science (London, England : 1979). 105(5)
Interleukin-2 (IL-2), a cytokine that induces natural killer cells termed lymphokine-activated killer (LAK) cells, is in use as an anticancer agent. During IL-2 therapy, adverse effects, such as vasodilatation and hypotension, are common. Previous st
Autor:
Sung Oog, Kim, Kunal, Merchant, Raphael, Nudelman, Wayne F, Beyer, Teresa, Keng, Joseph, DeAngelo, Alfred, Hausladen, Jonathan S, Stamler
Publikováno v:
Cell. 109(3)
Redox regulation has been perceived as a simple on-off switch in proteins (corresponding to reduced and oxidized states). Using the transcription factor OxyR as a model, we have generated, in vitro, several stable, posttranslational modifications of
Publikováno v:
Free radical biologymedicine. 28(10)
Hemoglobins modified for therapeutic use as either hemoglobin-based oxygen carriers or scavengers of nitric oxide are currently being evaluated in clinical trials. One such product, pyridoxalated hemoglobin polyoxyethylene conjugate (PHP), is a human
Autor:
Veronica Nwosu, Christopher T. Privalle, Sanjay Jain, Nalini M. Motwani, Michael J. Holland, Todd L. Talarico, Wajeeh Bajwa, Joseph DeAngelo, Robert Blackburn, Teresa Keng
Publikováno v:
Protein expression and purification. 8(4)
Hemoglobin Rainier is a naturally occurring hemoglobin variant in which the beta 145 tyrosine is substituted with cysteine. The alpha and beta Rainier globin cDNAs were cloned in a high copy number vector and expressed in Saccharomyces cerevisiae und
Publikováno v:
Cell. 86(5)
Hydrogen peroxide (H 2 O 2 ) imposes an oxidative stress to Escherichia coli that is manifested by oxidation of glutathione and related redox-sensitive targets. OxyR is a thiol-containing transcriptional activator whose oxidation controls the express
Autor:
Siqing Shan, Joseph Deangelo, Mark W. Dewhirst, Robert E. Meyer, Joseph Bonaventura, Edgardo T. Ong, Richard K. Dodge
Publikováno v:
British Journal of Cancer
We examined the microvascular effects of competitive nitric oxide synthase (NOS) inhibition with NG-monomethyl-L-arginine (MeArg), followed by L-arginine, on R3230Ac mammary adenocarcinoma perfusion. In window preparations containing tumours, superfu
Publikováno v:
Chest. 126:779S