Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joseph Davide"'
Development of process analytical tools for rapid monitoring of live virus vaccines in manufacturing
Autor:
Sijia Yi, Reilly McCracken, Joseph Davide, Daniel Ryan Salovich, Travis Whitmer, Aditya Bhat, Josef Vlasak, Sha Ha, Darrell Sehlin, Joseph Califano, Kristin Ploeger, Malini Mukherjee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract In the development of end-to-end large-scale live virus vaccine (LVV) manufacturing, process analytical technology (PAT) tools enable timely monitoring of critical process parameters (CPP) and significantly guide process development and char
Externí odkaz:
https://doaj.org/article/e6e04a053d5a4be59f82f4a832c5d1ea
Autor:
Geoffri Ricci, Kevin Minsker, Austin Kapish, James Osborn, Sha Ha, Joseph Davide, Joseph P. Califano, Darrell Sehlin, Richard R. Rustandi, Lawrence W. Dick, Josef Vlasak, Timothy D. Culp, Andreas Baudy, Edward Bell, Malini Mukherjee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Direct at line monitoring of live virus particles in commercial manufacturing of vaccines is challenging due to their small size. Detection of malformed or damaged virions with reduced potency is rate-limited by release potency assays with l
Externí odkaz:
https://doaj.org/article/6fd2905286724233b97e09383c9378da
Autor:
Bruce Ng, Tanesha Cash-Mason, Yi Wang, Jessica Seitzer, Julja Burchard, Duncan Brown, Vadim Dudkin, Joseph Davide, Vasant Jadhav, Laura Sepp-Lorenzino, Pedro J. Cejas
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 194-205 (2019)
Clinical application of siRNA-based therapeutics outside of the liver has been hindered by the inefficient delivery of siRNA effector molecules into extra-hepatic organs and cells of interest. To understand the parameters that enable RNAi activity in
Externí odkaz:
https://doaj.org/article/6ad8ee93c61c45c1a058a2bb051c2398
Autor:
Reilly McCracken, Joseph Davide, Daniel Salovich, Travis Whitmer, Aditya Bhat, Josef Vlasak, Sha Ha, Sijia Yi, Malini Mukherjee, Darrell Sehlin, Kristin Ploeger, Joseph Califano
In the development of end-to-end large-scale live virus vaccine (LVV) manufacturing, process analytical technology (PAT) tools enable timely monitoring of critical process parameters (CPP) and significantly guide process development and characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40828b037fd7d3b13f257da692e82485
https://doi.org/10.21203/rs.3.rs-1486921/v1
https://doi.org/10.21203/rs.3.rs-1486921/v1
Autor:
Theresa M. Williams, Jeffrey M. Bergman, Karen Brashear, Michael J. Breslin, Christopher J. Dinsmore, John H. Hutchinson, Suzanne C. MacTough, Craig A. Stump, Donna D. Wei, C. Blair Zartman, Michael J. Bogusky, J. Christopher Culberson, Carolyn Buser-Doepner, Joseph Davide, Ian B. Greenberg, Kelly A. Hamilton, Kenneth S. Koblan, Nancy E. Kohl, Dongming Liu, Robert B. Lobell, Scott D. Mosser, Timothy J. O'Neill, Elaine Rands, Michael D. Schaber, Francine Wilson, Edith Senderak, Sherri L. Motzel, Jackson B. Gibbs, Samuel L. Graham, David C. Heimbrook, George D. Hartman, Allen I. Oliff, Joel R. Huff
Publikováno v:
Journal of medicinal chemistry. 42(19)