Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joseph D. Meyers"'
Autor:
Malcolm E. Kenney, Joseph D. Meyers, Jonathan E. Kiechle, Gopolakrishnan Ramamurthy, Ping Zhang, Lee Ponsky, Brian Tsui, James P. Basilion, Xinning Wang
Publikováno v:
Molecular Cancer Therapeutics. 15:1834-1844
Prostatectomy has been the mainstay treatment for men with localized prostate cancer. Surgery, however, often can result in major side effects, which are caused from damage and removal of nerves and muscles surrounding the prostate. A technology that
Publikováno v:
Nanomedicine. 8:123-143
Brain cancer tumors cause disruption of the selective properties of vascular endothelia, even causing disruptions in the very selective blood–brain barrier, which are collectively referred to as the blood–brain–tumor barrier. Nanoparticles (NPs
Autor:
Malcolm E. Kenney, Yu Cheng, Xinning Wang, Ann-Marie Broome, Richard S. Agnes, Mark D. Schluchter, Seunghee Margevicius, James P. Basilion, Joseph D. Meyers, Clemens Burda
Publikováno v:
Particleparticle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems. 32(4)
Targeted drug delivery using epidermal growth factor peptide-targeted gold nanoparticles (EGFpep-Au NPs) is investigated as a novel approach for delivery of photodynamic therapy (PDT) agents, specifically Pc 4, to cancer. In vitro studies of PDT show
Autor:
Randall Toy, Andrew Camann, Joseph D. Meyers, Elliott Hayden, Pubudu M. Peiris, Efstathios Karathanasis, Hanping Wu, Peter Vicente, Emily Tran, David L. Wilson, Agata A. Exner, Jenna Pansky, Ketan B. Ghaghada, Zachary Berman
Publikováno v:
ACS nano. 7(4)
Tumors present numerous biobarriers to the successful delivery of nanoparticles. Decreased blood flows and high interstitial pressures in tumors dictate the degree of resistance to extravasation of nanoparticles. To understand how a nanoparticle can
Autor:
Chunying Wu, Liang Yan Xue, Gregory T. MacLennan, Joseph D. Meyers, Mark D. Schluchter, Hesheng Wang, Baowei Fei
Publikováno v:
Proceedings of SPIE--the International Society for Optical Engineering. 7262
We are developing and evaluating choline molecular imaging with positron emission tomography (PET) for monitoring tumor response to photodynamic therapy (PDT) in animal models. Human prostate cancer (PC-3) was studied in athymic nude mice. A second-g
Autor:
Joseph D. Meyers, Richard S. Agnes, Yu Cheng, Clemens Burda, Ann-Marie Broome, James P. Basilion, Tennyson L. Doane, Malcolm E. Kenney
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 7(16)
EGF-modified Au NP-Pc 4 conjugates showed 10-fold improved selectivity to the brain tumor compared to untargeted conjugates. The hydrophobic photodynamic therapy drug Pc 4 can be delivered efficiently into glioma brain tumors by EGF peptide-targeted
Autor:
Joseph D. Meyers, Yu Cheng, Malcolm E. Kenney, Ann-Marie Broome, James P. Basilion, Clemens Burda
Efficient drug delivery to tumors is of ever increasing importance. Single-visit diagnosis and treatment sessions are the goal of future theranostics. In this paper, a non-covalent PDT cancer drug-gold nanoparticle (Au NP) conjugate system performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fccec96d410d4a72b2069d9e9864d3
https://europepmc.org/articles/PMC3056176/
https://europepmc.org/articles/PMC3056176/
Autor:
Joseph D. Meyers, Yu Cheng, Baowei Fei, Clemens Burda, Anna Cristina S. Samia, Irene Panagopoulos
Publikováno v:
Journal of the American Chemical Society. 130(32)
A highly efficient drug vector for photodynamic therapy (PDT) drug delivery was developed by synthesizing PEGylated gold nanoparticle conjugates, which act as a water-soluble and biocompatible "cage" that allows delivery of a hydrophobic drug to its
Autor:
Jeffrey L. Duerk, Denise K. Feyes, Joseph D. Meyers, Nancy L. Oleinick, Baowei Fei, Hesheng Wang
Introduction: High-field magnetic resonance imaging (MRI) is an emerging technique that provides a powerful, non-invasive tool for in vivo studies of cancer therapy in animal models. Photodynamic therapy (PDT) is a relatively new treatment modality f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7b2909331a132a321f90cc20f41229
https://europepmc.org/articles/PMC2719260/
https://europepmc.org/articles/PMC2719260/
Autor:
Jeffrey L. Duerk, Denise K. Feyes, Nancy Edgehouse, Xiang Chen, Thomas G. Pretlow, John Mulvihill, Nancy L. Oleinick, Baowei Fei, Joseph D. Meyers, Hesheng Wang
We are developing in vivo small animal imaging techniques that can measure early effects of photodynamic therapy (PDT) for prostate cancer. PDT is an emerging therapeutic modality that continues to show promise in the treatment of cancer. At our inst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a851fde45c1e3ddbdb6263800f17d8f1
https://europepmc.org/articles/PMC3877221/
https://europepmc.org/articles/PMC3877221/