Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joseph D. Layne"'
Autor:
Jennifer M. Lang, Leslie R. Sedgeman, Lei Cai, Joseph D. Layne, Zhen Wang, Calvin Pan, Richard Lee, Ryan E. Temel, Aldons J. Lusis
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The gut microbiome influences nutrient processing as well as host physiology. Plasma lipid levels have been associated with the microbiome, although the underlying mechanisms are largely unknown, and the effects of dietary lipids on the gut microbiom
Externí odkaz:
https://doaj.org/article/4e2cf84c24634462855dfffa9e348351
Autor:
Calvin Pan, Joseph D. Layne, Leslie R. Sedgeman, Aldons J. Lusis, Lei Cai, Richard G. Lee, Ryan E. Temel, Zhen Wang, Jennifer M. Lang
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine, Vol 8 (2021)
The gut microbiome influences nutrient processing as well as host physiology. Plasma lipid levels have been associated with the microbiome, although the underlying mechanisms are largely unknown, and the effects of dietary lipids on the gut microbiom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc0b4b75305d76fe7c30375b6f2c8a2
http://europepmc.org/articles/PMC8426918
http://europepmc.org/articles/PMC8426918
Publikováno v:
Journal of Biological Chemistry. 290:7851-7860
Group X secretory phospholipase A2 (GX sPLA2) hydrolyzes mammalian cell membranes, liberating free fatty acids and lysophospholipids. GX sPLA2 is produced as a pro-enzyme (pro-GX sPLA2) that contains an N-terminal 11-amino acid propeptide ending in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a758663b8367523ccb48f9e1bc03ef9
https://doi.org/10.1074/jbc.m114.634667
https://doi.org/10.1074/jbc.m114.634667
Autor:
Ching-Yi Hu, Joseph D. Layne, Ryan E. Temel, Shahrazd Hashemi, Lei Cai, Zhen Wang, Margery A. Connelly, Irina Shalaurova, Waleed Aljaaidi, Courtney R. Burkett, Imroz H. Apon, Peter I. Hecker, Morgan R. Kelley, Sierra M. Schlicht, Tong Li, Tara E. Keenan, Nishita Meshram
Publikováno v:
Atherosclerosis Supplements. 32:19-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85afae0da846cf9510910bc87aae11d2
https://doi.org/10.1016/j.atherosclerosissup.2018.04.057
https://doi.org/10.1016/j.atherosclerosissup.2018.04.057
Autor:
Courtney R. Burkett, Lei Cai, Joseph D. Layne, Richard G. Lee, Ryan E. Temel, Sierra M Paxton
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Excessive accumulation of cholesterol in the arteries drives atherosclerosis development. It is believed that biliary cholesterol secretion is crucial for eliminating excess cholesterol from the body via reverse cholesterol transport. In the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b450df08800f434fd4e4625969a0d0
https://doi.org/10.1161/atvb.36.suppl_1.439
https://doi.org/10.1161/atvb.36.suppl_1.439
Autor:
Joseph D Layne, Allison L McDaniel, Stephanie M Marshall, Kylie Kavanagh, Christine C Esau, Kathryn J Moore, Ryan E Temel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Elevated plasma low-density lipoprotein (LDL) and decreased high-density lipoprotein (HDL) cholesterol levels increase the risk of cardiovascular disease (CVD). While strategies to lower LDL cholesterol have been successful in reducing CVD-related mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17cff8af115fbb0292d6bb7e9a5b08c5
https://doi.org/10.1161/atvb.35.suppl_1.127
https://doi.org/10.1161/atvb.35.suppl_1.127
Publikováno v:
The Journal of biological chemistry. 289(40)
Group X secretory phospholipase A2 (GX sPLA2) potently hydrolyzes membrane phospholipids to release arachidonic acid (AA). While AA is an activator of glucose-stimulated insulin secretion (GSIS), its metabolite prostaglandin E2 (PGE2) is a known inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91b9e27dbd80b4371d7f3245870a963
https://pubmed.ncbi.nlm.nih.gov/25122761
https://pubmed.ncbi.nlm.nih.gov/25122761
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Group X secretory phospholipase A2 (GX sPLA2) hydrolyzes phospholipids within membrane bilayers, liberating free fatty acids and lysophospholipids. We reported previously that C57BL/6 mice deficient in GX sPLA2 (GX KO) have increased plasma corticost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8d1a5537ecec82262bfd55b6b9c55db
https://doi.org/10.1161/atvb.33.suppl_1.a432
https://doi.org/10.1161/atvb.33.suppl_1.a432
Dietary intervention strategies have proven to be an effective means of decreasing several risk factors associated with the development of atherosclerosis. Endothelial cell dysfunction influences vascular inflammation and is involved in promoting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4965a1a3b239b396c8fed0864bed7a
https://europepmc.org/articles/PMC3139026/
https://europepmc.org/articles/PMC3139026/
Autor:
Andrew J. Morris, Bernhard Hennig, Manjula Sunkara, Joseph D. Layne, Zuzana Majkova, Michal Toborek
Coplanar polychlorinated biphenyls (PCBs) may facilitate development of atherosclerosis by stimulating pro-inflammatory pathways in the vascular endothelium. Nutrition, including fish oil-derived long-chain omega-3 fatty acids, such as docosahexaenoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0df9eb4d8d1225cb4e0fa565ba7744
https://europepmc.org/articles/PMC3026064/
https://europepmc.org/articles/PMC3026064/