Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joseph D. Garlick"'
Autor:
Ali Bootwala, Hyun Hwan An, Meghan Whitney Franklin, Benjamin J. Manning, Lucy Y. Xu, Shruti Panchal, Joseph D. Garlick, Reshica Baral, Michael E. Hudson, Gevorg Grigoryan, Mark A. Murakami, Kristen Hopson, Daniel S. Leventhal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The optimal use of many biotherapeutics is restricted by Anti-drug antibodies (ADAs) and hypersensitivity responses which can affect potency and ability to administer a treatment. Here we demonstrate that Re-surfacing can be utilized as a generalizab
Externí odkaz:
https://doaj.org/article/4a3b4c9302ed43f8bcb616f28001d45c
Publikováno v:
Journal of Biological Chemistry. 285:4645-4651
ATP-dependent chromatin remodeling complexes rearrange nucleosomes by altering the position of DNA around the histone octamer. Although chromatin remodelers and the histone variant H2A.Z colocalize on transcriptional control regions, whether H2A.Z di
Publikováno v:
Biochemistry. 47:7025-7033
SNF2h-based ATP-dependent chromatin remodeling complexes diverge in composition, nuclear localization, and biological function. Such differences have led to the hypothesis that SNF2h complexes differ mechanistically. One proposal is that the complexe
Autor:
Karim-Jean Armache, Christopher P. Davis, Daniel J. Grau, Robert E. Kingston, Jason A. West, Matthew D. Simon, Joseph D. Garlick
Publikováno v:
The FASEB Journal. 27
Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge
Autor:
Robert E. Kingston, Nicole J. Francis, Brad Chapman, Joseph D. Garlick, Daniel J. Grau, Mark L. Borowsky
Publikováno v:
Genesdevelopment. 25(20)
Polycomb group (PcG) proteins are required for the epigenetic maintenance of developmental genes in a silent state. Proteins in the Polycomb-repressive complex 1 (PRC1) class of the PcG are conserved from flies to humans and inhibit transcription. On
Publikováno v:
Genesdevelopment. 22(10)
p55 is a common component of many chromatin-modifying complexes and has been shown to bind to histones. Here, we present a crystal structure of Drosophila p55 bound to a histone H4 peptide. p55, a predicted WD40 repeat protein, recognizes the first h