Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Joseph D. Fondell"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/28baf0e864a94659b4ba4183fc37ed48
Autor:
Bin Lu, Yuxuan Wang, Wurihan Wurihan, Andrew Cheng, Sydney Yeung, Joseph D. Fondell, Zhao Lai, Danny Wan, Xiang Wu, Wei Vivian Li, Huizhou Fan
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTChlamydia, an obligate intracellular bacterial pathogen, has a unique developmental cycle involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate bodies (RBs), replication of RBs, and redifferentiation of
Externí odkaz:
https://doaj.org/article/c8bd7ca2456945f8947fc0e14ccb330e
Autor:
Andrew Cheng, Danny Wan, Arkaprabha Ghatak, Chengyuan Wang, Deyu Feng, Joseph D. Fondell, Richard H. Ebright, Huizhou Fan
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Gene transcription in bacteria is carried out by the multisubunit RNA polymerase (RNAP), which is composed of a catalytic core enzyme and a promoter-recognizing σ factor. The core enzyme comprises two α subunits, one β subunit, one β′
Externí odkaz:
https://doaj.org/article/e33bc81ba9064c8e9615bb14dc4c9865
Autor:
Yehong Huang, Wurihan Wurihan, Bin Lu, Yi Zou, Yuxuan Wang, Korri Weldon, Joseph D. Fondell, Zhao Lai, Xiang Wu, Huizhou Fan
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of heat shock sigma factors and activation of genes normally repres
Externí odkaz:
https://doaj.org/article/0d6dbe42c9924491b1adb212c1d66485
Publikováno v:
PPAR Research, Vol 2010 (2010)
The peroxisome proliferator-activated receptor-𝛼 (PPAR𝛼) plays a key role in lipid metabolism and energy combustion. Chronic activation of PPAR𝛼 in rodents leads to the development of hepatocellular carcinomas. The ability of PPAR𝛼 to ind
Externí odkaz:
https://doaj.org/article/bcfa2688f6b44824aed2e8688757eaf0
Autor:
Joseph D. Fondell, Cory Abate-Shen, Michael M. Ittmann, Marina Chekmareva, Madesh Belakavadi, Wei Yu, Shazia Irshad, Feng Jin
PDF file - 529K, Fig. S1. MED1 antibody specificity. Fig. S2. Anti-phospho-MED1 antibody specificity. Fig. S3. Inhibition of ERK or AKT signaling decreases MED1 phosphorylation and expression in prostate cancer cells. Fig. S4. Phospho-MED1 binds to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524a8cfd63089d32200a22c453295e49
https://doi.org/10.1158/1541-7786.22510099.v1
https://doi.org/10.1158/1541-7786.22510099.v1
Autor:
Joseph D. Fondell, Cory Abate-Shen, Michael M. Ittmann, Marina Chekmareva, Madesh Belakavadi, Wei Yu, Shazia Irshad, Feng Jin
MED1 is a key coactivator of the androgen receptor (AR) and other signal-activated transcription factors. Whereas MED1 is overexpressed in prostate cancer cell lines and is thought to coactivate distinct target genes involved in cell-cycle progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fa49ad8ec0af6abc8be54dcbb220e7
https://doi.org/10.1158/1541-7786.c.6539506.v1
https://doi.org/10.1158/1541-7786.c.6539506.v1
Supplementary Figures 1-2 from A Coregulatory Role for the Mediator Complex in Prostate Cancer Cell Proliferation and Gene Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed3af6167e33676a6b3d159da426f04
https://doi.org/10.1158/0008-5472.22368612.v1
https://doi.org/10.1158/0008-5472.22368612.v1
Androgen receptor (AR) signaling pathways are important for the survival and proliferation of prostate cancer cells. Because AR activity is facilitated by distinct coregulatory factors and complexes, it is conceivable that some of these proteins migh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594cd9e5e1ca71a546d2feb4284ccdff
https://doi.org/10.1158/0008-5472.c.6496032.v1
https://doi.org/10.1158/0008-5472.c.6496032.v1
Hallmarks of the developmental cycle of the obligate intracellular pathogenic bacteriumChlamydiaare the primary differentiation of the infectious elementary body (EB) cell type into the proliferative reticulate body (RB) and the secondary differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbfed0bb5e6ff0263a714a4efd5f98b2
https://doi.org/10.1101/2023.03.09.531986
https://doi.org/10.1101/2023.03.09.531986