Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Joseph D Santangelo"'
Autor:
Shi-Hsia Hwa, Yock Ann Lee, Joseph N Brewoo, Charalambos D Partidos, Jorge E Osorio, Joseph D Santangelo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 11, p e2538 (2013)
Human enterovirus 71 (EV71) is a significant cause of morbidity and mortality from Hand, Foot and Mouth Disease (HFMD) and neurological complications, particularly in young children in the Asia-Pacific region. There are no vaccines or antiviral thera
Externí odkaz:
https://doaj.org/article/eeb616478f0b4a30941c4fb365f20f6c
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59501 (2013)
Non-polio enteroviruses, including enterovirus 71 (EV71), have caused severe and fatal cases of hand, foot and mouth disease (HFMD) in the Asia-Pacific region. The development of a vaccine or antiviral against these pathogens has been hampered by the
Externí odkaz:
https://doaj.org/article/49b6499375cc44eab595eaef56ab7a89
Autor:
Chau Bich Nguyen Tran, Hieu Trong Nguyen, Ha Thanh Thi Phan, Ngoc Van Tran, Bridget Wills, Jeremy Farrar, Joseph D Santangelo, Cameron P Simmons
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21116 (2011)
Enterovirus 71 (EV71)-associated hand, foot and mouth disease has emerged as a serious public health problem in South East Asia over the last decade. To better understand the prevalence of EV71 infection, we determined EV71 seroprevalence and seroinc
Externí odkaz:
https://doaj.org/article/d670cec9be094075b93bc16754b8c0da
Autor:
Raman Rao, Paul A. Tambyah, Lovkesh Karwal, Hansi Dean, Jolene Oon, William Kristanto, Joseph D. Santangelo, Shi-Hsia Hwa, Fue Vang, Subash C. Das, Jeremy Fuchs, Rosmonaliza Asli, Dan T. Stinchcomb, Cynthia A. Thomson, Gilad Gordon
Publikováno v:
Vaccine. 37:4344-4353
Background Hand, foot and mouth disease (HFMD), especially that caused by enterovirus 71 (EV71) infection, is a public health concern in the Asia-Pacific region. We report a phase I clinical trial of an EV71 candidate vaccine (INV21) based on a binar
Autor:
Gilad Gordon, Mary Kathryn Smith, Marsha Raanan, Richard E. Rupp, Gary J. Luckasen, Jorge E. Osorio, Derek Wallace, Joseph D. Santangelo, Dan T. Stinchcomb, Judith Lee Kirstein
Publikováno v:
Vaccine. 33(46)
Introduction A safe, effective dengue vaccine that can simultaneously induce immunity to all four dengue virus serotypes (DENV-1–4) is a public health priority. A chimeric tetravalent dengue vaccine (TDV) based on an attenuated DENV-2 serotype back
Autor:
Rebecca Kerry Wilson, Lane Jonathan Douglas, Andrew Topping, Joseph D. Santangelo, Robert G. Feldman, Phillip J. Muckett, Zabin N. Younes, Joanne C. Moore, Richard Dobson, Hughes Martin John Glenton, Philippa K. Pribul
Publikováno v:
FEMS Microbiology Letters. 222:263-271
Using an alkaline phosphatase-based genetic screening method, we identified a number of proteins that are potentially located on the outer surface of Group B streptococcus (Streptococcus agalactiae). In an enzyme-linked immunosorbent assay, antisera
Autor:
Jaqueline E. Shea, David Lewis, J. D. Johnson, Derek Pickard, Gordon Dougan, Jo Phillimore, Joseph D. Santangelo, Zoë Hindle, Marjan Ghaem-Maghami, Robert G. Feldman, Matthew Bentley, David W. Holden, Steven N. Chatfield, Tao Wu, Shahid A. Khan, Mohammad Akbar Khan, George E. Griffin, Amy Sexton, Catherine Cosgrove, Deborah House, Frank R. Brennan, Paul Everest
Publikováno v:
Infection and Immunity. 70:3457-3467
The attenuation and immunogenicity of two novel Salmonella vaccine strains, Salmonella enterica serovar Typhi (Ty2 Δ aroC Δ ssaV , designated ZH9) and S. enterica serovar Typhimurium (TML Δ aroC Δ ssaV , designated WT05), were evaluated after the
Autor:
Shawn Silengo, Jaclyn Scott, Karen L. Boroughs, Dan T. Stinchcomb, Iván D. Vélez, Alejandra Jiménez, Jorge E. Osorio, Janae L. Stovall, Betty E. Luy, Mark E. Beatty, Aurelia Haller, Claire Y.-H. Huang, Joseph D. Santangelo, Gilad Gordon, Liliana Lopez, Cynthia A. Thomson, John Arguello
Publikováno v:
The Lancet. Infectious diseases. 14(9)
Summary Background Dengue virus is the most serious mosquito-borne viral threat to public health and no vaccines or antiviral therapies are approved for dengue fever. The tetravalent DENVax vaccine contains a molecularly characterised live attenuated
Publikováno v:
Current Opinion in Microbiology. 3:451-458
Signature-tagged mutagenesis is a functional genomics technique that identifies microbial genes required for infection within an animal host, or within host cells. The application of this technique to a range of microbial pathogens has resulted in th
Sporulation and time course expression of sigma-factor homologous genes inClostridium acetobutylicum
Publikováno v:
FEMS Microbiology Letters. 161:157-164
The gene for the vegetative sigma factor A of Clostridium acetobutylicum was constitutively transcribed during growth and formed an operon together with dnaE. Sporulation-specific sigma factors E, G, and K were sequentially induced shortly before mat