Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Joseph D Dekker"'
Autor:
Alessandra Machado Araujo, Joseph D Dekker, Kendra Garrison, Zhe Su, Catherine Rhee, Zicheng Hu, Bum-Kyu Lee, Daniel Osorio, Jiwon Lee, Vishwanath R Iyer, Lauren IR Ehrlich, George Georgiou, Gregory Ippolito, Stephen Yi, Haley O Tucker
Publikováno v:
eLife, Vol 13 (2024)
We identified a novel mouse plasmacytoid dendritic cell (pDC) lineage derived from the common lymphoid progenitors (CLPs) that is dependent on expression of Bcl11a. These CLP-derived pDCs, which we refer to as ‘B-pDCs’, have a unique gene express
Externí odkaz:
https://doaj.org/article/80e19280b37e44668886ed8fca1eecca
Autor:
Tara L Rasmussen, Yanlin Ma, Chong Yon Park, June Harriss, Stephanie A Pierce, Joseph D Dekker, Nicolas Valenzuela, Deepak Srivastava, Robert J Schwartz, M David Stewart, Haley O Tucker
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121765 (2015)
Smyd1/Bop is an evolutionary conserved histone methyltransferase previously shown by conventional knockout to be critical for embryonic heart development. To further explore the mechanism(s) in a cell autonomous context, we conditionally ablated Smyd
Externí odkaz:
https://doaj.org/article/6474b35f28774de6a4df747fea3aeed0
Autor:
Jianzhi Zhao, Hanjun Li, Rujiang Zhou, Gang Ma, Joseph D Dekker, Haley O Tucker, Zhengju Yao, Xizhi Guo
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131674 (2015)
Hair follicle stem cells (HFSCs) in the bugle circularly generate outer root sheath (ORS) through linear proliferation within limited cycles during anagen phases. However, the mechanisms controlling the pace of HFSC proliferation remain unclear. Here
Externí odkaz:
https://doaj.org/article/5e734a05f4a148318f83039bbd0a31ff
Autor:
Cecil M Benitez, Kun Qu, Takuya Sugiyama, Philip T Pauerstein, Yinghua Liu, Jennifer Tsai, Xueying Gu, Amar Ghodasara, H Efsun Arda, Jiajing Zhang, Joseph D Dekker, Haley O Tucker, Howard Y Chang, Seung K Kim
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004645 (2014)
The regulatory logic underlying global transcriptional programs controlling development of visceral organs like the pancreas remains undiscovered. Here, we profiled gene expression in 12 purified populations of fetal and adult pancreatic epithelial c
Externí odkaz:
https://doaj.org/article/012a70afd9b449a890f49665fe50730b
Autor:
Garrett L. Cornelison, Ileana Pedraza, Kendra Garrison, Elizabeth M. Kapeel, Channing Pletka, Abdul Khan, Jessica Momb, Rebecca Martin, Adam Bartos, Joseph D. Dekker, Jay Zhao, John Majercak, Garrett L. Robinson
Publikováno v:
Cancer Research. 83:P4-08
Engineered Toxin Bodies Specific for TROP2 Positive Cancers Authors: Garrett L. Cornelison, Ileana Pedraza, Kendra Garrison, Elizabeth M. Kapeel, Channing Pletka, Abdul Khan, Jessica Momb, Rebecca Martin, Adam Bartos, Joseph D. Dekker, Jay Zhao, John
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41848d10fe5100e4f2a8781c7f5b4dee
https://doi.org/10.1158/1538-7445.sabcs22-p4-08-18
https://doi.org/10.1158/1538-7445.sabcs22-p4-08-18
Autor:
Joseph D. Dekker, Melissa A. Edwards, Huimin Geng, Mark A. Brown, Haley O. Tucker, Ilham Alshiraihi
Publikováno v:
Genes and immunity, vol 21, iss 2
Genes and immunity
Genes and immunity
The five membered SET and MYND Domain-containing lysine methyltransferase (SMYD) family plays pivotal roles in development and proliferation. Initially characterized within the cardiovascular system, one such member, SMYD2, has been implicated as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8837e22505fb5dbc50d79cf6ae98c1c0
https://doi.org/10.1038/s41435-020-0094-8
https://doi.org/10.1038/s41435-020-0094-8
Autor:
Garrett L. Cornelison, Adam Bartos, Brigitte Brieschke, Jessica Momb, Ileana Pedraza, Elizabeth M. Kapeel, Rebecca Martin, Channing Pletka, Adrian Gonzalez, Joseph D. Dekker, Jay Zhao, John Majercak, Garrett L. Robinson
Publikováno v:
Cancer Research. 82:326-326
Engineered toxin bodies (ETBs) are comprised of a proprietarily engineered form of Shiga-like Toxin A subunit (SLT-A) genetically fused to antibody-like binding domains. ETBs work through novel mechanisms of action and are capable of forced internali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5f2fe9c76ae838b6b9164c80a0f1ce5
https://doi.org/10.1158/1538-7445.am2022-326
https://doi.org/10.1158/1538-7445.am2022-326
Autor:
Swati Khanna, Elizabeth M. Kapeel, Lauren R. Byrne, Elizabeth Saputra, Steven Rivera, Lindsey Aschenbach, Lilia A. Rabia, Garrett L. Cornelison, Rachael M. Orlandella, Brigitte Brieschke, Michaela Sousares, Jay Zhao, Garrett L. Robinson, Chris Moore, Joseph D. Dekker
Publikováno v:
Cancer Research. 82:3543-3543
Targeting of PD-L1 checkpoint has shown clinical efficacy in multiple solid tumor indications. Currently approved PD-L1 targeted approaches rely on the blocking activity of monoclonal antibodies (mAbs) which sterically inhibit PD-L1 thus preventing P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2dbc19c675d76e5455c7b7a21f5cb7
https://doi.org/10.1158/1538-7445.am2022-3543
https://doi.org/10.1158/1538-7445.am2022-3543
Autor:
Rachael M. Orlandella, Elizabeth M. Kapeel, Brigitte Brieschke, Garrett L. Robinson, Joseph D. Dekker, Chris B. Moore
Publikováno v:
Cancer Research. 82:2579-2579
Engineered Toxin Bodies (ETBs) represent a unique therapeutic strategy for fighting cancer by targeting and selectively destroying cancer cells or cancer-promoting immune cells. Featuring an antibody-based targeting domain fused with the cytotoxic, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3fff8b659798cf01b12c7413b267c6
https://doi.org/10.1158/1538-7445.am2022-2579
https://doi.org/10.1158/1538-7445.am2022-2579
Autor:
Caleigh Howard, Shu Wiley, Wenzhao Dong, Andrea Mendiola, Veronica Partridge, Sara LeMar, Paul Amador, Amit K. Chaudhary, Joseph D. Dekker, Jay Zhao, Ross Durland, Aimee Iberg
Publikováno v:
Cancer Research. 82:335-335
Engineered toxin bodies (ETBs) are next-generation immunotoxins that harbor an antibody-derived targeting domain and a cytotoxic payload derived from Shiga-like toxin-1 catalytic subunit A (SLTA). SLTA has been engineered to reduce innate immunogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48bf0f44bbe00d6e794c14f27458ec55
https://doi.org/10.1158/1538-7445.am2022-335
https://doi.org/10.1158/1538-7445.am2022-335