A SNP Based Linkage Map of the Arctic Charr (Salvelinus alpinus) Genome Provides Insights into the Diploidization Process After Whole Genome Duplication

Autor: Cameron M. Nugent, Anne A. Easton, Joseph D. Norman, Moira M. Ferguson, Roy G. Danzmann

Publikováno v: G3: Genes, Genomes, Genetics, Vol 7, Iss 2, Pp 543-556 (2017)

Diploidization, which follows whole genome duplication events, does not occur evenly across the genome. In salmonid fishes, certain pairs of homeologous chromosomes preserve tetraploid loci in higher frequencies toward the telomeres due to residual t

Externí odkaz: https://doaj.org/article/300331bc46204920a6020b2e0b6a26b4

A genetic linkage map for the salmon louse (Lepeophtheirus salmonis): evidence for high male:female and inter-familial recombination rate differences

Autor: Sigbjørn Lien, Amber M. Messmer, Roy G. Danzmann, Matthew Peter Kent, Ben F. Koop, Okechukwu O. Igboeli, Eric Rondeau, Joseph D. Norman, Mark D. Fast

Publikováno v: Molecular Genetics and Genomics

A salmon louse (Lepeophtheirus salmonis salmonis) genetic linkage map was constructed to serve as a genomic resource for future investigations into the biology of this important marine parasitic copepod species, and to provide insights into the inher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263eeff6f517f0a17c959454c0f4ff7c
https://hdl.handle.net/11250/2663712

A 200K SNP chip reveals a novel Pacific salmon louse genotype linked to differential efficacy of emamectin benzoate

Autor: David R. Minkley, Brad Boyce, Eric Rondeau, Mark D. Fast, Diane Morrison, Sigbjørn Lien, Anita Mueller, Ben F. Koop, Matthew Peter Kent, Jong S. Leong, Cody A. Despins, Amber M. Messmer, Joseph D. Norman, Roy G. Danzmann

Publikováno v: Marine Genomics

Antiparasitic drugs such as emamectin benzoate (EMB) are relied upon to reduce the parasite load, particularly of the sea louse Lepeophtheirus salmonis, on farmed salmon. The decline in EMB treatment efficacy for this purpose is an important issue fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af73dd08f9c134a1a239aa52e000a10
https://pubmed.ncbi.nlm.nih.gov/29673959

A SNP Based Linkage Map of the Arctic Charr (

Autor: Cameron M, Nugent, Anne A, Easton, Joseph D, Norman, Moira M, Ferguson, Roy G, Danzmann

Publikováno v: G3: Genes|Genomes|Genetics

Diploidization, which follows whole genome duplication events, does not occur evenly across the genome. In salmonid fishes, certain pairs of homeologous chromosomes preserve tetraploid loci in higher frequencies toward the telomeres due to residual t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::920f1c83ef83eebca5b79fcbbee677be
https://pubmed.ncbi.nlm.nih.gov/27986793

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Autor: Constanze Zeller, Joseph D. Norman, Man Yu, Jian Qiang Lu, Doug Strother, Miklós Garami, C. Jane McGlade, Seung-Ki Kim, Misko Dzamba, Ronald Grant, David D. Eisenstat, Beverly Wilson, Anat Erdreich-Epstein, Almos Klekner, A. Sorana Morrissy, Richard Grundy, Young Shin Ra, Joanna J. Phillips, Alexandre Montpetit, Takafumi Wataya, Alexander R. Judkins, Shayna Zelcer, Nicholas K. Foreman, Rishi Lulla, Aline Cristiane Planello, Marc Remke, Harriet Druker, Annie Huang, Torsten Pietsch, José Pimentel, Jordan R. Hansford, Lindsey M. Hoffman, Mark Barszczyk, Tarik Tihan, Eugene Hwang, Vivek Mehta, László Bognár, Louis Letourneau, Donna L. Johnston, Stephen Yip, Lucie Lafay-Cousin, Mei Lu, Pasqualino De Antonellis, Katrin Scheinemann, Deena M.A. Gendoo, Shengrui Feng, James T. Rutka, G. Yancey Gillespie, Ho Keung Ng, Robert Hammond, David Malkin, Lúcia Roque, Anne Sophie Carret, King Ching Ho, Helen Toledano, Jennifer A. Chan, Monika Warmuth-Metz, Jacek Majewski, Jonathon Torchia, Livia Garzia, Stefan Rutkowski, Gino R. Somers, Tibor Hortobágyi, Ute Bartels, Peter Hauser, Ulrich Schüller, Cynthia Hawkins, Shih Hwa Chiou, Eric Bouffet, Adam Fleming, Alexandra N. Riemenschneider, Timothy E. Van Meter, Vijay Ramaswamy, Hideo Nakamura, Tiago Medina, Alexandre Vasiljevic, Noppadol Larbcharoensub, Patrick Sin-Chan, Christopher Dunham, Theodore Nicolaides, Iris Fried, Daniel Picard, Maryam Fouladi, Chris Fryer, Brian Golbourn, Mathieu Bourgey, Jean Michaud, Claudia C. Faria, Gary D. Bader, Mathieu Lupien, Amar Gajjar, Guillaume Bourque, Peter B. Dirks, Steffen Albrecht, Suradej Hongeng, Cheryl H. Arrowsmith, Uri Tabori, David A. Ramsay, Dalia Barsyte-Lovejoy, Paul Guilhamon, Michael Brudno, Nada Jabado, Juliette Hukin, Dong Anh Khuong-Quang, Michael D. Taylor, Tiffany Chan, Natalia R. Agamez, Daniel D. De Carvalho, Nongnuch Sirachainan, Samina Afzal, Seung Ah Choi, Diane K. Birks, Daniel W. Fults, Andrew S. Moore, Alyssa Reddy, Jason Fangusaro, Daniel Catchpoole, Yin Wang

We recently reported that atypical teratoid rhabdoid tumors (ATRTs) comprise at least two transcriptional subtypes with different clinical outcomes; however, the mechanisms underlying therapeutic heterogeneity remained unclear. In this study, we anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd543284281a8a171f42d71d0b75da35