Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joseph Contessa"'
Autor:
Debra Nana Yeboa, James B. Yu, Eric Liao, Jason Huse, Marta Penas-Prado, Benjamin H. Kann, Erik Sulman, David Grosshans, Joseph Contessa
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 15, Iss , Pp 46-52 (2019)
Molecular markers are redefining classification of lower grade gliomas and ushering in a paradigm shift in their management. Our objective was to evaluate the differences in pattern of care and outcome by comparing grade II and grade III molecularly
Externí odkaz:
https://doaj.org/article/df95c6f17c62464885fb6d3862af7e84
Autor:
Yajing Liu, Sahezeel Awadia, Amy Delaney, Merna Sitto, Carl G. Engelke, Heli Patel, Andrew Calcaterra, Sylvia Zelenka-Wang, Hojin Lee, Joseph Contessa, Nouri Neamati, Mats Ljungman, Theodore S. Lawrence, Meredith A. Morgan, Alnawaz Rehemtulla
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100834- (2020)
The Unfolded Protein Response (UPR) plays a key role in the adaptive response to loss of protein homeostasis within the endoplasmic reticulum (ER). The UPR has an adaptive function in protein homeostasis, however, sustained activation of the UPR due
Externí odkaz:
https://doaj.org/article/8565fd736ec64fb4919739945b14f89d
Autor:
Elsenoor Klaver, Peng Zhao, Melanie May, Heather Flanagan-Steet, Hudson H. Freeze, Reid Gilmore, Lance Wells, Joseph Contessa, Richard Steet
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 6 (2019)
Global inhibition of N-linked glycosylation broadly reduces glycan occupancy on glycoproteins, but identifying how this inhibition functionally impacts specific glycoproteins is challenging. This limits our understanding of pathogenesis in the congen
Externí odkaz:
https://doaj.org/article/71db76a11e90405f8d9d510bf04c122f
Purpose:Parallel signaling reduces the effects of receptor tyrosine kinase (RTK)–targeted therapies in glioma. We hypothesized that inhibition of protein N-linked glycosylation, an endoplasmic reticulum co- and posttranslational modification crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a532ce4565a62b9c82bbcb7004936a95
https://doi.org/10.1158/1078-0432.c.6528881.v1
https://doi.org/10.1158/1078-0432.c.6528881.v1
Time course resolution of γH2AX foci formation in D54 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864403b9b5c33bb6271afbc120445f33
https://doi.org/10.1158/1078-0432.22474700
https://doi.org/10.1158/1078-0432.22474700
List of antibodies used in the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703f054a68ffa514c607fcfed736c0e5
https://doi.org/10.1158/1078-0432.22474706
https://doi.org/10.1158/1078-0432.22474706
Supplementary figures legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c67c8b09627ea985a88f5211f5b3a2c
https://doi.org/10.1158/1078-0432.22474697.v1
https://doi.org/10.1158/1078-0432.22474697.v1
Dose response of NGI-1, temozolomide and etoposide in glioma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a86bc7639148ccecfddf940adbdea3
https://doi.org/10.1158/1078-0432.22474703
https://doi.org/10.1158/1078-0432.22474703
Autor:
Jessie Li, Zhigui Li, Whitney Soble, Marta Baro, Hojin Lee, Shari Damast, Joseph Contessa, Gloria Huang
Publikováno v:
Gynecologic Oncology. 166:S128
Publikováno v:
Cancer Research. 82:3315-3315
Purpose: Although Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer worldwide, the high failure rates for non-HPV associated tumors and the absence of new effective therapies has caused the survival rate for HNSCC to remai