Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Joseph Castillo"'
Publikováno v:
Communication in Biomathematical Sciences, Vol 6, Iss 2, Pp 100-107 (2023)
Trend analysis plays an important role in infectious disease control. An analysis of the underlying trend in the number of cases or the mortality of a particular disease allows one to characterize its growth. Trend analysis may also be used to evalua
Externí odkaz:
https://doaj.org/article/19bbaee2706349dab997efe17098398d
Publikováno v:
Philippine Journal of Orthopaedics, Vol 39, Iss 1 (2024)
Objectives. Pertrochanteric fractures, commonly incurred by the elderly from low-energy falls, require surgical management. Visible blood loss in the perioperative period is inconsistent with the big drop in hemoglobin seen postoperatively. This disc
Externí odkaz:
https://doaj.org/article/c2453ae63e4f419ba245736648caeb28
Publikováno v:
AIMS Mathematics, Vol 7, Iss 10, Pp 19202-19220 (2022)
Data smoothing is a method that involves finding a sequence of values that exhibits the trend of a given set of data. This technique has useful applications in dealing with time series data with underlying fluctuations or seasonality and is commonly
Externí odkaz:
https://doaj.org/article/bb01a35767ab47f6a568dc278a688cd6
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
supplementary tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35073d94791ff25b6df92ad645e456c1
https://doi.org/10.1158/2326-6066.22543155.v1
https://doi.org/10.1158/2326-6066.22543155.v1
Supplementary Fig 1 from Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
TMB, TFB and CRPC scores across individual samples and disease stages and crosscorrelation analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9124389488a6abd15abccd6bbf624d28
https://doi.org/10.1158/2326-6066.22543161.v1
https://doi.org/10.1158/2326-6066.22543161.v1
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
Prostate cancer is the second leading cause of cancer-related death in men. Despite having a relatively lower tumor mutational burden than most tumor types, multiple gene fusions such as TMPRSS2:ERG have been characterized and linked to more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e25bc093bffce3f195eb2bcc044f33
https://doi.org/10.1158/2326-6066.c.6550161.v1
https://doi.org/10.1158/2326-6066.c.6550161.v1
Autor:
Mallika Singh, Klaus P. Hoeflich, Mark Merchant, Richard Carano, Dorothy French, Michelle A. Nannini, William Forrest, Tim Cao, Hani Bou-Reslan, Emily Chan, Douglas Den Otter, Anne C. Clermont, Ciara Metcalfe, Joseph Castillo, Jason H. Cheng, Vidusha Devasthali, Melissa R. Junttila
Supplemental Fig 1,2,3. Tumor growth rates, overall survival and single agent GDC-0973 in vitro response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71abcd86d84e987877a60f47e42d7d98
https://doi.org/10.1158/1535-7163.22501464
https://doi.org/10.1158/1535-7163.22501464
Autor:
Mallika Singh, Klaus P. Hoeflich, Mark Merchant, Richard Carano, Dorothy French, Michelle A. Nannini, William Forrest, Tim Cao, Hani Bou-Reslan, Emily Chan, Douglas Den Otter, Anne C. Clermont, Ciara Metcalfe, Joseph Castillo, Jason H. Cheng, Vidusha Devasthali, Melissa R. Junttila
Activating mutations in the KRAS oncogene occur in approximately 90% of pancreatic cancers, resulting in aberrant activation of the MAPK and the PI3K pathways, driving malignant progression. Significant efforts to develop targeted inhibitors of nodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec601dfc57c36d50faff96ead5e30713
https://doi.org/10.1158/1535-7163.c.6536796.v1
https://doi.org/10.1158/1535-7163.c.6536796.v1
Autor:
Matthew T. Burger, Jocelyn Holash, Richard Zang, J. Alex Aycinena, Cornelia Bellamacina, Mika Lindvall, Gisele Nishiguchi, Jiong Lan, Wooseok Han, Christopher Wilson, Joerg Trappe, Peter Drueckes, Estelle Pfister, Audrey Kauffmann, Christine Fritsch, Tiffany Tsang, Jamie Narberes, Robert Warne, Paul Feucht, Michael Doyle, Jianjun Yu, Julie Chan, Stephen Basham, Xiao-Hong Niu, Jing Lu, Yumin Dai, Tatiana Zavorotinskaya, Marjorie Ison, Christie Fanton, Joseph Castillo, Min Chen, Yingyun Wang, John L. Langowski, Pablo D. Garcia
Purpose: PIM kinases have been shown to act as oncogenes in mice, with each family member being able to drive progression of hematologic cancers. Consistent with this, we found that PIMs are highly expressed in human hematologic cancers and show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b7a0911566c282b44322df88773977
https://doi.org/10.1158/1078-0432.c.6522398
https://doi.org/10.1158/1078-0432.c.6522398
Autor:
Zineb Mounir, Mark R. Lackner, Jennifer M. Giltnane, Vicki Plaks, Shih-Min A. Huang, Steven Magnuson, F. Anthony Romero, Andrew Glibicky, Thomas Holcomb, Somayeh S. Tarighat, Matthew P. Stokes, Wendell Jones, Katherine E. Hutchinson, Bonnie Liu, Jeffrey Eastham-Anderson, Melissa Gonzalez Edick, Sangeeta Jayakar, Marie-Claire Wagle, Ron McCord, Shrividhya Srinivasan, Christopher Lowe, Esther Wu, Joseph Castillo
Supplementary figure 3 shows H3K27 acetylation ChIPseq QC analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477ddd9560eda30f5c026406d5682a9e
https://doi.org/10.1158/0008-5472.22421168.v1
https://doi.org/10.1158/0008-5472.22421168.v1