Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joseph C.K. Lee"'
Publikováno v:
Pathology. 48:S67-S68
Autor:
Joseph C.K. Lee, Philip J. Johnson, Karen C.H. Zhoc, Yvonne Mak, Winnie Yeo, Charlotte Y.P. Li, Raymond S. K. Lo, Jean Woo
Publikováno v:
Palliative Medicine. 15:387-397
The main focus of palliative care services is to improve patients' quality of life (QOL). The potential value of assessment of QOL in palliative care is being increasingly recognized. The McGill Quality of Life questionnaire (MQOL) is designed specif
Publikováno v:
International Journal of Medical Informatics. 61:97-101
A global 24-hour telemedicine conference entitled, “Moving with the Sun” was successfully completed on June 30 and July 1 1997 between participants from Hong Kong and China, as well as with sixteen major international medical centres around the g
Publikováno v:
Blood. 95:1942-1949
We prospectively analyzed p15 and p16 promoter methylation patterns using methylation-specific polymerase chain reaction (PCR) in patients with adult and childhood acute leukemias and studied the association of methylation patterns with chromosomal a
Autor:
G L Wang, Kwok Wai Lo, Kam Sze Tsang, Siu Tim Cheung, Joseph C.K. Lee, Dolly P. Huang, Yuen-Shan Tsang, N Y F Chung
Publikováno v:
British Journal of Cancer
The p16 gene, encodes a key checkpoint protein p16 in the cell cycle, has been reported inactivation in a wide variety of human cancers. We have previously demonstrated high frequency of p16 alterations in primary nasopharyngeal carcinoma (NPC), xeno
Autor:
Chuen Wai Ko, Dolly P. Huang, Nathalie Wong, Kwok Wai Lo, Yuen Shan Tsang, Angela B.Y. Hui, Bruce M. Whitney, Siu Tim Cheung, Joseph C.K. Lee
Publikováno v:
ResearcherID
We have established a cell line (C666-1) from undifferentiated nasopharyngeal carcinoma (NPC). This cell line consistently carries the Epstein-Barr virus (EBV) in long-term cultures. C666-1 is a subclone of its parental cell line, C666, derived from
Autor:
Joseph C.K. Lee, Peter M.L. Teo, K. F. To, Kwok Wai Lo, Dolly P. Huang, Michael K.F. Fung, Angela Bik Yu Hui, Sing Fai Leung, Peter H.K. Choi, Nathalie Wong
Publikováno v:
International Journal of Cancer. 82:498-503
Nasopharyngeal carcinoma (NPC) is a common cancer in Southern China but rare in Western countries. To search for genetic alterations in NPC, we examined a series of 20 primary tumours with comparative genomic hybridisation. The identified common chro
Autor:
Paul B.S. Lai, Kwok Wai Lo, Lin-Yee Hin, C.K. Leow, Choong Tsek Liew, Xiao-qiu Wang, Shan Wu, Hiu Ming Li, Joseph C.K. Lee, Boon Kian Lim, Wan Yee Lau, John Y.H. Chan
Publikováno v:
International Journal of Cancer. 81:319-324
Hepatocellular carcinoma (HCC) is a common malignancy worldwide and highly associated with chronic virus-B or -C infection and cirrhosis. Molecular studies have shown high frequency of loss of heterozygosity (LOH) in some specific chromosome regions,
Autor:
Siu Tim Cheung, K. W. Chiu, Tai Fai Fok, Kwok Wai Lo, Sing Fai Leung, Dolly P. Huang, Joseph C.K. Lee, Philip J. Johnson, John S. Tam
Publikováno v:
International Journal of Cancer. 76:399-406
We reported previously that a characteristic Epstein-Barr virus latent membrane protein 1 (EBV-LMP1) gene was associated with nasopharyngeal carcinoma (NPC) in Hong Kong. It showed a 30 bp deletion at the carboxyl terminus with specific amino acid su
Publikováno v:
Blood. 89:2500-2506
Both p16 and p15, encoded by the genes located on chromosome 9p21, are inhibitors of cyclin-dependent kinases (CDK4/6) and the upstream regulators of Rb function. In hematopoietic malignancies, deletion of p16/p15 locus has been shown to be highly sp