Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joseph C. Sheffer"'
Autor:
John L. Macomber, Sorena Rahmanian, Robert A. Horlick, David J. King, Vladimir Spasojevic, Eric Hare, Xue Zhang, Audrey D. McConnell, Peter Bowers, Joseph C. Sheffer, Betty Chau
Publikováno v:
mAbs. 6:1274-1282
Antibody engineering to enhance thermostability may enable further application and ease of use of antibodies across a number of different areas. A modified human IgG framework has been developed through a combination of engineering approaches, which
Autor:
Ashley D. Berkebile, Audrey D. McConnell, Peter Bowers, Joseph C. Sheffer, John L. Macomber, David J. King, Steven S. Neben, Andy P. Chen, Robert A. Horlick, Irina P. Krapf, Vladimir Spasojevich
Publikováno v:
Protein Engineering Design and Selection. 26:151-164
Antibodies are important tools for a broad range of applications due to their high specificity and ability to recognize virtually any target molecule. However, in order to be practically useful, antibodies must be highly stable and bind their target