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pro vyhledávání: '"Joseph C. Reese"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 315-330 (2018)
The Ccr4 (carbon catabolite repression 4)-Not complex is a major regulator of stress responses that controls gene expression at multiple levels, from transcription to mRNA decay. Ccr4, a “core” subunit of the complex, is the main cytoplasmic dead
Externí odkaz:
https://doaj.org/article/2857384379184e739b8883b7812a9775
Publikováno v:
ACS Chem Biol
The nucleosome is the basic packing unit of the eukaryotic genome. Dynamic interactions between DNA and histones in the nucleosome are the molecular basis of gene accessibility regulation that governs the kinetics of various DNA-templated processes s
Autor:
Joseph C. Reese
Publikováno v:
Methods. :1-3
Publikováno v:
DNA Repair (Amst)
Degradation Factor 1 was discovered 20 years ago as a yeast protein copurifying with Rad26, a helicase involved in transcription-coupled DNA repair. It was subsequently shown to control the ubiquitylation and destruction of the large subunit of DNA d
Autor:
Stefania Trazzi, Giovanni Perini, Roberto Bernardoni, Monica Zoli, Joseph C Reese, Andrea Musacchio, Giuliano Della Valle
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5832 (2009)
CENP-C is a fundamental component of functional centromeres. The elucidation of its structure-function relationship with centromeric DNA and other kinetochore proteins is critical to the understanding of centromere assembly. CENP-C carries two region
Externí odkaz:
https://doaj.org/article/57ac3be007154c9da0cbaad9bd3136e9
The Ccr4–Not complex regulates essentially every aspect of gene expression, from mRNA synthesis to protein destruction. The Not4 subunit of the complex contains an E3 RING domain and targets proteins for ubiquitin-dependent proteolysis. Ccr4–Not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44149dadde7618342ae06a0cbdbf29b
https://europepmc.org/articles/PMC6546055/
https://europepmc.org/articles/PMC6546055/
Transcription elongation through the nucleosome is a precisely coordinated activity to ensure timely production of RNA and accurate regulation of co-transcriptional histone modifications. Nucleosomes actively participate in transcription regulation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709e70101f8cff14614221e319e0619d
https://europepmc.org/articles/PMC6589119/
https://europepmc.org/articles/PMC6589119/
Autor:
J. Brooks Crickard, Joseph C. Reese
Publikováno v:
Methods (San Diego, Calif.).
Transcription of DNA into RNA is critical for all life, and RNA polymerases are enzymes tasked with this activity. In eukaryotes, RNA Polymerase II (RNAPII) is responsible for transcription of all protein coding genes and many non-coding RNAs. RNAPII
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 315-330 (2018)
G3: Genes, Genomes, Genetics, Vol 8, Iss 1, Pp 315-330 (2018)
The Ccr4 (carbon catabolite repression 4)-Not complex is a major regulator of stress responses that controls gene expression at multiple levels, from transcription to mRNA decay. Ccr4, a “core” subunit of the complex, is the main cytoplasmic dead
Publikováno v:
Journal of Biological Chemistry. 289:33125-33130
Gene expression relies on the balance between mRNA synthesis in the nucleus and decay in the cytoplasm, processes once thought to be separate. We now know that transcription and decay rates are coordinated, but the factors or molecular mechanisms are