Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Joseph C. Nolan"'
1
Low-dose esterified estrogen therapy: effects on bone, plasma estradiol concentrations, endometrium, and lipid levels. Estratab/Osteoporosis Study Group
Autor: Mark Akin, Hwa Ming Yang, Stuart R. Weiss, Nelson B. Watts, John J. Brennan, Ronald Emkey, Joseph Mortola, Joseph C. Nolan, J. Lucas, Robert W. Downs, Niranyan Banav, Harry K. Genant, Heidi McNaney-Flint
Publikováno v: Archives of Internal Medicine. 157:2609-2615
Background Prospective studies have shown that doses equivalent to conjugated equine estrogens of 0.625 mg/d or higher are needed to produce a significant increase in bone mineral density of the lumbar spine. Objectives To determine the effects of un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ce3f6788b17dd35d9cd6f1088e8138c
https://doi.org/10.1001/archinte.157.22.2609
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2
Bioavailability of silicon and aluminum from Zeolite A in dogs
Autor: Denise Lowe Walters, Eugenio A. Cefali, Joseph C. Nolan, William R. McConnell
Publikováno v: International Journal of Pharmaceutics. 127:147-154
A study in beagle dogs was carried out to estimate the bioavailability of silicon and aluminum from Zeolite A administered as a capsule, oral suspension, and oral solution relative to an intravenous bolus infusion (i.v.) administered over a 1-1.5 min
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11bdf6c79c419698d70541e7f6302736
https://doi.org/10.1016/0378-5173(95)04110-9
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3
[Untitled]
Autor: Eugenio A. Cefali, Denise Lowe Walters, Joseph C. Nolan, William R. McConnell
Publikováno v: Pharmaceutical Research. 12:270-274
Zeolite A is a synthetic zeolite which may have therapeutic utility in osteoporotic individuals because of its ability to stimulate bone formation. A study of Zeolite A (30 mg/kg), sodium aluminosilicate (16 mg/kg), magnesium trisilicate (20 mg/kg),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73587a5b3e57c09fba2e830321749e03
https://doi.org/10.1023/a:1016291228957
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4
Induction of collagenase synthesis in chondrocytes by a factor synthesized by inflamed synovial tissue
Autor: Joseph C. Nolan, M. Jane Landes, Arnold L. Oronsky, Suresh S. Kerwar, Susan C. Ridge
Publikováno v: Agents and Actions. 43:206-210
Rabbit inflamed synovial tissue grown in culture synthesizes a factor that induces collagenase synthesis in chondrocytes and in cartilage. Synthesis of this factor by the synovial tissue is inhibited by cycloheximide but not by indomethacin. The fact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b969a66b37c2085671811d5357004a
https://doi.org/10.1007/bf01986690
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6
Carbonic anhydrase inhibitors are antiarthritic in the rat
Autor: Joseph C. Nolan, Carol E. Gathright, Cynthia H. Radvany, Lawrence F. Sancilio, Richard J. Barrett
Publikováno v: Pharmacological Research. 24:377-383
Adjuvant-induced arthritis in rats was attenuated by the therapeutic administration of carbonic anhydrase inhibitors. Female Lewis rats with established disease were treated daily (day 18 through day 50) with various carbonic anhydrase inhibitors; oe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b95c3a3a2d339ec188a786d42dac4e
https://doi.org/10.1016/1043-6618(91)90042-v
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7
Synthesis and antiallergy activity of N-[2-(dimethylamino)ethyl]-4-aryl-1-piperazinecarboxamide derivatives
Autor: David A. Walsh, Jerry B. Green, Stephen K. Franzyshen, Joseph C. Nolan, John M. Yanni
Publikováno v: Journal of Medicinal Chemistry. 33:2028-2032
A series of N-[2-(dimethylamino)ethyl]-4-aryl-1-piperazinecarboxamides was synthesized and evaluated for antiallergy activity. Several derivatives had activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe2d9cc821d0672a53506deab8e11cd
https://doi.org/10.1021/jm00169a037
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8
The synthesis and antiallergy activity of 1-(aryloxy)-4-(4-arylpiperazinyl)-2-butanol derivatives
Autor: David A. Walsh, John M. Yanni, Joseph C. Nolan, Jerry B. Green, Ying Ho Chen
Publikováno v: Journal of Medicinal Chemistry. 33:1823-1827
A series of 1-(aryloxy)-4-(4-arylpiperazinyl)-2-butanol derivatives were prepared and evaluated for antiallergy activity in the passive foot anaphylaxis (PFA) assay in rats. Twenty-seven derivatives had activity equal to or greater than the parent, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9502737f2349c356fd2074f9ba34223f
https://doi.org/10.1021/jm00168a044
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10
Synthesis and physicochemical properties of sulfamate derivatives as topical antiglaucoma agents
Autor: Young S. Lo, David F. Gripshover, Dwight A. Shamblee, Joseph C. Nolan, William J. Welstead, Thomas H. Maren
Publikováno v: Journal of medicinal chemistry. 35(26)
Several imidazolylphenyl sulfamate and (imidazolylphenoxy)alkyl sulfamate derivatives were synthesized and evaluated as topically active carbonic anhydrase inhibitors. Water solubility, pKa, carbonic anhydrase inhibition, and partition coefficient fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76b41e524a24006a6e19a86eb855d4c
https://pubmed.ncbi.nlm.nih.gov/1479580
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