Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joseph C. Grieco"'
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 38-46 (2016)
Angelman syndrome (AS) is a rare genetic and neurological disorder presenting with seizures, developmental delay, ataxia, and lack of speech. Previous studies have indicated that oxidative stress-dependent metabolic dysfunction may underlie the pheno
Externí odkaz:
https://doaj.org/article/0c47e62a9c154abf8c06e0b380b4b76c
Autor:
Edwin J. Weeber, Joseph C. Grieco, Sarah E. Harris, Heather A. Born, Angelique Regnier-Golanov, Luis A. Martinez, Anne E. Anderson
Publikováno v:
Clinical EEG and Neuroscience. 54:203-212
The goal of these studies was to use quantitative (q)EEG techniques on data from children with Angelman syndrome (AS) using spectral power analysis, and to evaluate this as a potential biomarker and quantitative method to evaluate therapeutics. Altho
Publikováno v:
Journal of Applied Research in Intellectual Disabilities
Journal of Applied Research in Intellectual Disabilities, Wiley, 2018, 31 (6), pp.1219-1224. ⟨10.1111/jar.12462⟩
Journal of Applied Research in Intellectual Disabilities, Wiley, 2018, 31 (6), pp.1219-1224. ⟨10.1111/jar.12462⟩
International audience; BackgroundAngelman syndrome (AS) leads to clinical manifestations that include intellectual impairments, developmental delay and poor motor function. Initiatives to develop therapeutics implie an urgent need to identify method
Autor:
Edwin J. Weeber, Joseph C. Grieco, Laura Conover, Lauren N. Mackie, Ruth Huntley Bahr, Mike R. Schoenberg
Publikováno v:
Journal of Applied Research in Intellectual Disabilities. 31:e49-e58
Background Angelman syndrome is a rare disorder in which most individuals do not develop speech. Testing of communication ability using traditional neuropsychological measures reveals a performance level at or near the floor of the instrument resulti
Autor:
Jessica L. Banko, Edwin J. Weeber, Anne E. Anderson, Whitney R. Hethorn, Danielle Gulick, Daniela Aguirre, Stephanie L. Ciarlone, Irina Filonova, Justin T. Rogers, Melinda M. Peters, Joseph C. Grieco, Raquel A. Ramirez, April L. Lussier
Publikováno v:
The European Journal of Neuroscience
The Reelin signaling pathway is implicated in processes controlling synaptic plasticity and hippocampus-dependent learning and memory. A single direct in vivo application of Reelin enhances long-term potentiation, increases dendritic spine density an
Autor:
Alison E. Willing, Keith R. Pennypacker, Joseph C. Grieco, Tracy A. Womble, M. Shahaduzzaman, Suzanne M. Green, Paul R. Sanberg
Publikováno v:
Molecular and cellular neurosciences. 59
Systemic administration of human umbilical cord blood (HUCB) mononuclear cells (MNC) following middle cerebral artery occlusion (MCAO) in the rat reduces infarct size and, more importantly, restores motor function. The HUCB cell preparation is compos
Autor:
Amanda Smith, Helen Heussler, Edwin J. Weeber, Stephanie L. Ciarlone, Mike R. Schoenberg, Rex M. Philpot, Maria Gieron-Korthals, Joseph C. Grieco, Jessica L. Banko
Publikováno v:
BMC Neurology
Background Minocycline, a member of the tetracycline family, has a low risk of adverse effects and an ability to improve behavioral performance in humans with cognitive disruption. We performed a single-arm open-label trial in which 25 children diagn