Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Joseph C Mudd"'
Autor:
Maria Pino, Sara Paganini, Claire Deleage, Kartika Padhan, Justin L Harper, Colin T King, Luca Micci, Barbara Cervasi, Joseph C Mudd, Kiran P Gill, Sherrie M Jean, Kirk Easley, Guido Silvestri, Jacob D Estes, Constantinos Petrovas, Michael M Lederman, Mirko Paiardini
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008081 (2019)
Lymph nodes (LN) and their resident T follicular helper CD4+ T cells (Tfh) are a critical site for HIV replication and persistence. Therefore, optimizing antiviral activity in lymphoid tissues will be needed to reduce or eliminate the HIV reservoir.
Externí odkaz:
https://doaj.org/article/317b112ab6a540088ba22b5560bb1102
Autor:
Joseph C. Mudd
Publikováno v:
Viruses, Vol 16, Iss 4, p 514 (2024)
The persistence of the latent viral reservoir is the main hurdle to curing HIV-1 infection. SIV infection of non-human primates (NHPs), namely Indian-origin rhesus macaques, is the most relevant and widely used animal model to evaluate therapies that
Externí odkaz:
https://doaj.org/article/e09f594e60b346fe97a15441dcdb30a2
Autor:
Amin Izadpanah, Joseph C. Mudd, Joe G. N. Garcia, Sudesh Srivastav, Mohamed Abdel-Mohsen, Clovis Palmer, Aaron R. Goldman, Jay K. Kolls, Xuebin Qin, Jay Rappaport
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSevere COVID-19 results initially in pulmonary infection and inflammation. Symptoms can persist beyond the period of acute infection, and patients with Post-Acute Sequelae of COVID (PASC) often exhibit a variety of symptoms weeks or month
Externí odkaz:
https://doaj.org/article/e6397cf7b85b4dc0bf1a3ddf781f1494
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(2)
African green monkeys (AGMs), Chlorocebus pygerythrus, are a natural host for a lentivirus related to HIV, SIV. SIV-infected AGMs rarely progress to AIDS despite robust viral replication. Though multiple mechanisms are involved, a primary component i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36af70942f1ac4ca447f557cc4a2065d
https://pubmed.ncbi.nlm.nih.gov/35750337
https://pubmed.ncbi.nlm.nih.gov/35750337
Autor:
Celeste Coleman, Lara A. Doyle-Meyers, Kasi E. Russell-Lodrigue, Nadia Golden, Breanna Threeton, Kejing Song, Genevieve Pierre, Carl Baribault, Rudolf P. Bohm, Nicholas J. Maness, Jay K. Kolls, Jay Rappaport, Joseph C. Mudd
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Understanding SARS-CoV-2 immune pathology is critical for the development of effective vaccines and treatments. Here, we employed unbiased serial whole-blood transcriptome profiling by weighted gene network correlation analysis (WGCNA) at pre-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e460e190f1ae95cfbe26c798a3c8751c
http://europepmc.org/articles/PMC8527883
http://europepmc.org/articles/PMC8527883
Autor:
Nell G, Bond, Marissa D, Fahlberg, Shan, Yu, Namita, Rout, Dollnovan, Tran, Taylor, Fitzpatrick-Schmidt, Lesli M, Sprehe, Elizabeth A, Scheef, Joseph C, Mudd, Robert, Schaub, Amitinder, Kaur
Publikováno v:
iScience. 25(3)
Invariant natural killer T-lymphocytes (iNKT) are unique immunomodulatory innate T cells with an invariant TCRα recognizing glycolipids presented on MHC class-I-like CD1d molecules. Activated iNKT rapidly secrete pro-and anti-inflammatory cytokines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f251336cb04c02ff73a53b84639795d
https://pubmed.ncbi.nlm.nih.gov/35243248
https://pubmed.ncbi.nlm.nih.gov/35243248
Autor:
Sara Gianella, Stephen R. Morris, Cheryl M. Cameron, Souheil-Antoine Younes, Soumya Panigrahi, Carey L Shive, Bonnie Chen, Joseph C. Mudd, Benigno Rodriguez, Michael M. Lederman, David A. Zidar, Michael L. Freeman, Nicholas T. Funderburg, Scott F. Sieg
Publikováno v:
JCI Insight
HIV infection is associated with an increase in the proportion of activated CD8(+) memory T cells (Tmem) that express CX3CR1, but how these cells are generated and maintained in vivo is unclear. We demonstrate that increased CX3CR1 expression on CD8(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baad7c545dbc50aa489afd02875518d
https://doi.org/10.1172/jci.insight.132963
https://doi.org/10.1172/jci.insight.132963
Autor:
Rachel L. Rutishauser, Peter W. Hunt, Kyle A. Raymond, Daniel C. Douek, Theodore L. Roth, Rafick-Pierre Sekaly, Frederick Hecht, Alexander Marson, Carly E. Starke, Franziska Blaeschke, Steven G. Deeks, Christian Deo T Deguit, Christopher D. Pilcher, Joseph Hiatt, Joseph C. Mudd, Wenxuan Chen, Carolyn P Smullin, Joseph M. McCune, Satish K. Pillai, Melissa R. Krone, Richard A. Koup, Rebecca Hoh, Jeffrey N. Martin, Jason M. Brenchley, Lynn Wang, Rodrigo Matus-Nicodemos
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 3 (2021)
JCI insight, vol 6, iss 3
JCI Insight, Vol 6, Iss 3 (2021)
JCI insight, vol 6, iss 3
Although many HIV cure strategies seek to expand HIV-specific CD8+ T cells to control the virus, all are likely to fail if cellular exhaustion is not prevented. A loss in stem-like memory properties (i.e., the ability to proliferate and generate seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929b63af29587eb6cb7889bf025bb4cb
https://pubmed.ncbi.nlm.nih.gov/33351785
https://pubmed.ncbi.nlm.nih.gov/33351785
Autor:
Nell G. Bond, Marissa D. Fahlberg, Shan Yu, Namita Rout, Dollnovan Tran, Taylor Fitzpatrick-Schmidt, Lesli M. Sprehe, Elizabeth A. Scheef, Joseph C. Mudd, Robert Schaub, Amitinder Kaur
Publikováno v:
iScience. 25:103889
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8ea0520c1656a4a98784ab70cb20fd
https://doi.org/10.1016/j.isci.2022.103889
https://doi.org/10.1016/j.isci.2022.103889