Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Joseph C Holt"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Electrical stimulation of the mammalian efferent vestibular system (EVS) predominantly excites primary vestibular afferents along two distinct time scales. Although roles for acetylcholine (ACh) have been demonstrated in other vertebrates, s
Externí odkaz:
https://doaj.org/article/9865fec0c051471fa187db8068af281e
Autor:
David Lorincz, Lauren A. Poppi, Joseph C. Holt, Hannah R. Drury, Rebecca Lim, Alan M. Brichta
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2022)
The precise functional role of the Efferent Vestibular System (EVS) is still unclear, but the auditory olivocochlear efferent system has served as a reasonable model on the effects of a cholinergic and peptidergic input on inner ear organs. However,
Externí odkaz:
https://doaj.org/article/fea04b44b42c4d248b6a68913ac6a464
Autor:
Choongheon Lee, Anjali K. Sinha, Kenneth Henry, Anqi W. Walbaum, Peter A. Crooks, Joseph C. Holt
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Stimulation of cholinergic efferent neurons innervating the inner ear has profound, well-characterized effects on vestibular and auditory physiology, after activating distinct ACh receptors (AChRs) on afferents and hair cells in peripheral endorgans.
Externí odkaz:
https://doaj.org/article/dfac8bb09a75467bbd3ff706d394ec30
Autor:
Lauren A Poppi, Mark J Bigland, Ethan T Cresswell, Hessam Tabatabaee, David Lorincz, Hannah R Drury, Robert J Callister, Joseph C Holt, Rebecca Lim, Alan M Brichta, Doug W Smith
Publikováno v:
The Journals of Gerontology: Series A.
Cholinergic circuits in the central nervous system are vulnerable to age-related functional decline, but it is not known if aging impacts cholinergic signaling in the vestibular sensory organs, which are critically important to balance maintenance an
Autor:
Sherri M. Jones, Sarath Vijayakumar, Samantha A. Dow, Joseph C. Holt, Paivi M. Jordan, Anne E. Luebke
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Calcitonin gene-related peptide (CGRP) is a neuroactive peptide that is thought to play a role at efferent synapses in hair cell organs including the cochlea, lateral line, and semicircular canal. The deletion of CGRP in transgenic mice is associated
Externí odkaz:
https://doaj.org/article/93386142e14348538c2815ba79a7a79d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
In turtle posterior cristae, cholinergic vestibular efferent neurons (VENs) synapse on type II hair cells, bouton afferents innervating type II hair cells, and afferent calyces innervating type I hair cells. Electrical stimulation of VENs releases ac
Externí odkaz:
https://doaj.org/article/435715f39d7c4aef888e1f4b99ee04d0
Autor:
Shafaqat M. Rahman, Benjamin Liang, Stefanie Faucher, Elana Fine, Raajan Jonnala, Joseph C. Holt, Choongheon Lee, Anne E. Luebke
Migraine is a severe and chronic neurological disorder that affects ∼18% of people worldwide, the majority being female (3:1). It is characterized by recurrent, debilitating headaches and heightened sensory sensitivities. People with migraine may a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c996860a32cd3db00faa1f127e3a657c
https://doi.org/10.1101/2022.06.03.494764
https://doi.org/10.1101/2022.06.03.494764
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Electrical stimulation of the mammalian efferent vestibular system (EVS) predominantly excites primary vestibular afferents along two distinct time scales. Although roles for acetylcholine (ACh) have been demonstrated in other vertebrates, synaptic m
Publikováno v:
Biophys J
High sensitivity and selectivity of hearing require an active cochlea. The cochlear sensory epithelium, the organ of Corti, vibrates because of external and internal excitations. The external stimulation is acoustic pressures mediated by the scala fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10a8baddef278812b9bd7a69a43a91b
https://europepmc.org/articles/PMC7376138/
https://europepmc.org/articles/PMC7376138/
High sensitivity and selectivity of hearing require active cochlea. The cochlear sensory epithelium, the organ of Corti, vibrates due to external and internal excitations. The external stimulation is acoustic pressures mediated by the scala fluids, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55671c81287d59ca053c469b41d6f965