Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Joseph C Burns"'
Autor:
Keiji Honda, Sung Huhn Kim, Michael C Kelly, Joseph C Burns, Laura Constance, Xiangming Li, Fei Zhou, Michael Hoa, Matthew W Kelley, Philine Wangemann, Robert J Morell, Andrew J Griffith
Publikováno v:
eLife, Vol 6 (2017)
Mutations of SLC26A4 are a common cause of hearing loss associated with enlargement of the endolymphatic sac (EES). Slc26a4 expression in the developing mouse endolymphatic sac is required for acquisition of normal inner ear structure and function. H
Externí odkaz:
https://doaj.org/article/79806d70a13945af8dd52d996a2897bd
Autor:
Jonathan B. Sellon, Kathy S. So, Andrew D'Arcangelo, Sarah Cancelarich, Meghan C. Drummond, Peter G. Slade, Ning Pan, Tyler M. Gibson, Tian Yang, Joseph C. Burns, Adam T. Palermo, Lars Becker
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Deafness-causing deficiencies in otoferlin (OTOF) have been addressed preclinically using dual adeno-associated virus (AAV)-based approaches. However, timing of transduction, recombination of mRNA, and protein expression with dual hybrid AAV methods
Externí odkaz:
https://doaj.org/article/a844378fd26b47b3b6c0c1450c88a3a4
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48704 (2012)
The inner ears of adult humans and other mammals possess a limited capacity for regenerating sensory hair cells, which can lead to permanent auditory and vestibular deficits. During development and regeneration, undifferentiated supporting cells with
Externí odkaz:
https://doaj.org/article/8cfbf8df92f74ad0a56ce74c947a5aca
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23861 (2011)
When inner ear hair cells die, humans and other mammals experience permanent hearing and balance deficits, but non-mammalian vertebrates quickly recover these senses after epithelial supporting cells give rise to replacement hair cells. A postnatal d
Externí odkaz:
https://doaj.org/article/226560c5cf9645dfaf60d69400a47882
Publikováno v:
Biology Open, Vol 7, Iss 11 (2018)
The utricle of the inner ear, a vestibular sensory structure that mediates perception of linear acceleration, is comprised of two morphologically and physiologically distinct types of mechanosensory hair cells, referred to as Type Is and Type IIs. Wh
Externí odkaz:
https://doaj.org/article/8274365fdeb44836aebffc4863f70ede
Autor:
Adam T. Palermo, Matthew W. Kelley, Ronna Hertzano, Kathryn Ellis, Likhitha Kolla, Joseph C. Mays, Abigail Lemons, Elizabeth C. Driver, Joseph C. Burns, Alejandro Anaya-Rocha, Michael C. Kelly, Kathy S. So, Zoe F. Mann, Joshua Orvis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Mammalian hearing requires the development of the organ of Corti, a sensory epithelium comprising unique cell types. The limited number of each of these cell types, combined with their close proximity, has prevented characterization of individual cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df52876614f83c8b15361b3ff177205f
http://link.springer.com/article/10.1038/s41467-020-16113-y
http://link.springer.com/article/10.1038/s41467-020-16113-y
Autor:
Michal Sperber, Joseph C. Burns, Didier A. Depireux, Sunayana Mitra, Ronna Hertzano, Kathy S. So, Jonathan B. Sellon, Ran Elkon, Zachary Margulies, Christopher R. Cederroth, Heela Sarlus, Barbara Canlon, Joshua Orvis, Benjamin Shuster, Yoko Ogawa, Erika L. Lipford, Christopher Shults, Beatrice Milon, Eldad David Shulman, Yang Song, Gabriela Pregernig, Adam T. Palermo
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109758-(2021)
Cell reports
Cell reports
SUMMARY Noise-induced hearing loss (NIHL) results from a complex interplay of damage to the sensory cells of the inner ear, dysfunction of its lateral wall, axonal retraction of type 1C spiral ganglion neurons, and activation of the immune response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1429b77c1b05708ac2a85c862ceaa7
http://www.sciencedirect.com/science/article/pii/S2211124721012122
http://www.sciencedirect.com/science/article/pii/S2211124721012122
Autor:
Joseph C. Burns, Jennifer S. Stone
Publikováno v:
Seminars in Cell & Developmental Biology. 65:96-105
Vestibular sensation is essential for gaze stabilization, balance, and perception of gravity. The vestibular receptors in mammals, Type I and Type II hair cells, are located in five small organs in the inner ear. Damage to hair cells and their innerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96922e32310c128707b8a781596921a
https://doi.org/10.1016/j.semcdb.2016.11.001
https://doi.org/10.1016/j.semcdb.2016.11.001
Publikováno v:
Biology Open, Vol 7, Iss 11 (2018)
Biology Open
Biology Open
The utricle of the inner ear, a vestibular sensory structure that mediates perception of linear acceleration, is comprised of two morphologically and physiologically distinct types of mechanosensory hair cells, referred to as Type Is and Type IIs. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9104a59ad8800aef8b29e4a87e31c7d4
http://bio.biologists.org/content/7/11/bio038083
http://bio.biologists.org/content/7/11/bio038083
Autor:
Robert J. Morell, Fei Zhou, Keiji Honda, Michael Hoa, Matthew W. Kelley, Andrew J. Griffith, Michael C. Kelly, Joseph C. Burns, Sung Huhn Kim, Laura A. Constance, Philine Wangemann, Xiangming Li
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Mutations of SLC26A4 are a common cause of hearing loss associated with enlargement of the endolymphatic sac (EES). Slc26a4 expression in the developing mouse endolymphatic sac is required for acquisition of normal inner ear structure and function. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f9272cff020a7d2dc794d02eb13aad
http://europepmc.org/articles/PMC5634787
http://europepmc.org/articles/PMC5634787