Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joseph C, Ruiz"'
Autor:
Diana L. Carlone, Joseph C. Ruiz, Suzanne R.L. Young, David G. Skalnik, Jeong Heon Lee, Jill Sergesketter Butler, Erika A. Dobrota
Publikováno v:
Molecular and Cellular Biology. 25:4881-4891
The CpG dinucleotide is an important regulatory component of mammalian genomes. The cytosine of this dinucleotide serves as the target for methylation by DNA methyltransferase (Dnmt) enzymes, which functions as a critical epigenetic modification of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f5748a1232b17a78edd183000862b
https://doi.org/10.1128/mcb.25.12.4881-4891.2005
https://doi.org/10.1128/mcb.25.12.4881-4891.2005
Autor:
Angela, Stephenson, Guo-Ying, Huang, Gui-Yi, Huang, Ngoc-Thinh, Nguyen, Sean, Reuter, Jennifer L, McBride, Joseph C, Ruiz
Publikováno v:
Genomics. 83:1105-1115
msk, myocardial SNF1-like kinase, was originally isolated in a screen for kinases expressed during early cardiogenesis in the mouse. msk maps to the proximal end of mouse chromosome 17 in a region that is syntenic with human chromosome 21q22.3, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56357ab65e33e5f26ccf1df6533606fc
https://doi.org/10.1016/j.ygeno.2003.12.007
https://doi.org/10.1016/j.ygeno.2003.12.007
Autor:
Dana M. Brantley-Sieders, Donna J. Hicks, Ambra Pozzi, Joseph C. Ruiz, Justin Caughron, Jin Chen
Publikováno v:
Journal of Cell Science. 117:2037-2049
Angiogenesis is critical for vascular remodeling during development and contributes to the pathogenesis of diseases such as cancer. Targeted disruption of several EphB class receptor tyrosine kinases results in vascular remodeling defects during embr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448d87653c1ba3d3732326e1da15c1ec
https://doi.org/10.1242/jcs.01061
https://doi.org/10.1242/jcs.01061
Publikováno v:
Molecular and Cellular Biology. 22:4997-5005
Ubiquitin-mediated degradation targets cell cycle regulators for proteolysis. Much of the ubiquitin pathway's substrate specificity is conferred by E3 ubiquitin ligases, and cullins are core components of some E3s. CUL-4A encodes one of six mammalian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c2e544aa2ac847787d0939ce2e70dd
https://doi.org/10.1128/mcb.22.14.4997-5005.2002
https://doi.org/10.1128/mcb.22.14.4997-5005.2002
Autor:
Joseph C. Ruiz, Nancy A. Jenkins, Eiríkur Steingrímsson, George C. Prendergast, Nien Chen Mao, Wyeth W. Wasserman, James B. DuHadaway, Neal G. Copeland
Publikováno v:
Genomics. 56:51-58
We cloned and functionally characterized the murine Bin1 gene as a first step to investigate its physiological roles in differentiation, apoptosis, and tumorigenesis. The exon-intron organization of the/=55-kb gene is similar to that of the human gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3446c919064e9dfb6ee085187eb3ffc
https://doi.org/10.1006/geno.1998.5709
https://doi.org/10.1006/geno.1998.5709
Publikováno v:
Mechanisms of Development. 48:153-164
In Drosophila and Caenorhabditis, signal transduction pathways initiated by the activation of receptor-protein tyrosine kinases can mediate developmental fate decisions. In order to examine whether similar mechanisms are employed during mammalian emb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993d6de0ba17bfe7ba8eba8d93ce9f6a
https://doi.org/10.1016/0925-4773(94)90056-6
https://doi.org/10.1016/0925-4773(94)90056-6
Autor:
Joseph C, Ruiz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 702
The demand for primary human hepatocytes to test the toxicity of new drug candidates and to develop cell therapies for liver disease far exceed the number of hepatocytes that can be isolated from donated tissues. Less than 700 whole livers per year a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d59923a213c96c4720cec858c6615503
https://pubmed.ncbi.nlm.nih.gov/21082407
https://pubmed.ncbi.nlm.nih.gov/21082407
Autor:
Joseph C. Ruiz
Publikováno v:
Adipose-Derived Stem Cells ISBN: 9781617379598
The demand for primary human hepatocytes to test the toxicity of new drug candidates and to develop cell therapies for liver disease far exceed the number of hepatocytes that can be isolated from donated tissues. Less than 700 whole livers per year a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd52963d47c43bd3ca7d96386ab9380
https://doi.org/10.1007/978-1-61737-960-4_18
https://doi.org/10.1007/978-1-61737-960-4_18
Autor:
Geoffrey M. Wahl, Joseph C. Ruiz
Publikováno v:
Molecular and Cellular Biology. 10:3056-3066
Acentric extrachromosomal elements, such as submicroscopic autonomously replicating circular molecules (episomes) and double minute chromosomes, are common early, and in some cases initial, intermediates of gene amplification in many drug-resistant a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d723e7fe3b5092c93094648454d6ccb
https://doi.org/10.1128/mcb.10.6.3056-3066.1990
https://doi.org/10.1128/mcb.10.6.3056-3066.1990
Autor:
Jennifer L. McBride, Joseph C. Ruiz
Publikováno v:
Mechanisms of development. 77(2)
B61 (ephrin-A1), a ligand for eph receptor-protein tyrosine kinases, possesses angiogenic and endothelial cell chemoattractant activity. We report the expression profile of ephrin-A1 during mouse embryogenesis (7.25 to 10.5 days post-coitum (dpc)). E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed205921c3ea7e50a5945b0aa0e5b145
https://pubmed.ncbi.nlm.nih.gov/9831653
https://pubmed.ncbi.nlm.nih.gov/9831653