Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Joseph C, Masdeu"'
Autor:
Emily W Paolillo, Kaitlin B Casaletto, Annie L Clark, Jack C Taylor, Hilary W Heuer, Amy B Wise, Sreya Dhanam, Mark Sanderson-Cimino, Rowan Saloner, Joel H Kramer, John Kornak, Walter Kremers, Leah Forsberg, Brian Appleby, Ece Bayram, Andrea Bozoki, Danielle Brushaber, R Ryan Darby, Gregory S Day, Bradford C Dickerson, Kimiko Domoto-Reilly, Fanny Elahi, Julie A Fields, Nupur Ghoshal, Neill Graff-Radford, Matthew G H Hall, Lawrence S Honig, Edward D Huey, Maria I Lapid, Irene Litvan, Ian R Mackenzie, Joseph C Masdeu, Mario F Mendez, Carly Mester, Toji Miyagawa, Georges Naasan, Belen Pascual, Peter Pressman, Eliana Marisa Ramos, Katherine P Rankin, Jessica Rexach, Julio C Rojas, Lawren VandeVrede, Bonnie Wong, Zbigniew K Wszolek, Bradley F Boeve, Howard J Rosen, Adam L Boxer, Adam M Staffaroni
Publikováno v:
JMIR Aging, Vol 7, p e52831 (2024)
BackgroundFrontotemporal lobar degeneration (FTLD) is a leading cause of dementia in individuals aged
Externí odkaz:
https://doaj.org/article/e3a85b9c842b435281a2a70b74fac8bf
Autor:
Alireza Faridar, Abdulmunaim M. Eid, Aaron D. Thome, Weihua Zhao, David R. Beers, Maria B. Pascual, Mohammad O. Nakawah, Gustavo C. Roman, Charles S. Davis, Michael Grundman, Joseph C. Masdeu, Stanley H. Appel
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-4 (2023)
Trial registration ClinicalTrials.gov Identifier: NCT05821153, Registered April 20 2023, Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT05821153
Externí odkaz:
https://doaj.org/article/e8a0ebe6290e4359b7e72393eaf523ef
Autor:
Angela M. Ianni, Daniel P. Eisenberg, Erie D. Boorman, Sara M. Constantino, Catherine E. Hegarty, Michael D. Gregory, Joseph C. Masdeu, Philip D. Kohn, Timothy E. Behrens, Karen F. Berman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Foraging behavior requires weighing costs of time to decide when to leave one reward patch to search for another. Computational and animal studies suggest that striatal dopamine is key to this process; however, the specific role of dopamine
Externí odkaz:
https://doaj.org/article/8b16c463319b429da899f1c251095ffb
Anatomical localization skills based in physical examination are essential for any clinician caring for patients with neurologic disease processes. Now fully revised and up to date, Localization in Clinical Neurology, 8th Edition, uses easy-to-read d
Autor:
Alireza Faridar, Matthew Vasquez, Aaron D. Thome, Zheng Yin, Hui Xuan, Jing Hong Wang, Shixiang Wen, Xuping Li, Jason R. Thonhoff, Weihua Zhao, Hong Zhao, David R. Beers, Stephen T. C. Wong, Joseph C. Masdeu, Stanley H. Appel
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Background Regulatory T cells (Tregs) play a neuroprotective role by suppressing microglia and macrophage-mediated inflammation and modulating adaptive immune reactions. We previously documented that Treg immunomodulatory mechanisms are comp
Externí odkaz:
https://doaj.org/article/52b183fb078941b9b217ebdf26d36db7
Autor:
Jack Carson Taylor, Hilary W. Heuer, Annie L. Clark, Amy B. Wise, Masood Manoochehri, Leah Forsberg, Carly Mester, Meghana Rao, Daniell Brushaber, Joel Kramer, Ariane E. Welch, John Kornak, Walter Kremers, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Julie A. Fields, Nupur Ghoshal, Neill Graff‐Radford, Murray Grossman, Matthew GH Hall, Edward D. Huey, David Irwin, Maria I. Lapid, Irene Litvan, Ian R. Mackenzie, Joseph C. Masdeu, Mario F. Mendez, Naomi Nevler, Chiadi U. Onyike, Belen Pascual, Peter Pressman, Katherine P. Rankin, Buddhika Ratnasiri, Julio C. Rojas, Maria Carmela Tartaglia, Bonnie Wong, Maria Luisa Gorno‐Tempini, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Introduction Remote smartphone assessments of cognition, speech/language, and motor functioning in frontotemporal dementia (FTD) could enable decentralized clinical trials and improve access to research. We studied the feasibility and accept
Externí odkaz:
https://doaj.org/article/ddb1152f42564be09bd4bebba08f13f1
Autor:
Alan P. Pan, Jennifer Meeks, Thomas Potter, Joseph C. Masdeu, Sudha Seshadri, Matthew Lee Smith, Marcia G. Ory, Farhaan S. Vahidy
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Introduction: Persistent knowledge gaps exist as to the extent that preexisting cognitive impairment is a risk factor for susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and mortality from the coronavirus disease 2019 (
Externí odkaz:
https://doaj.org/article/027e227c0513447e97bc0df7102dc27b
Autor:
Aaron D. Thome, Alireza Faridar, David R. Beers, Jason R. Thonhoff, Weihua Zhao, Shixiang Wen, Belen Pascual, Joseph C. Masdeu, Stanley H. Appel
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Background Neuroinflammation is a hallmark of neurodegenerative disease and a significant component of the pathology of Alzheimer’s disease (AD). Patients present with extensive microgliosis along with elevated pro-inflammatory signaling i
Externí odkaz:
https://doaj.org/article/bd79f6c8e3194aba94dfcf283d6034b3
Autor:
Joseph C. Masdeu, Angela M. Ianni, Karen F. Berman, Philip Kohn, Michael D. Gregory, Bhaskar Kolachana, Catherine E. Hegarty, Daniel P. Eisenberg
Publikováno v:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 8:121-128
Background The rs1344706 single nucleotide polymorphism in the ZNF804A gene has been associated with risk for psychosis in multiple genome-wide association studies, yet mechanisms underlying this association are not known. Given preclinical work sugg
Publikováno v:
Journal of Nuclear Medicine. 63:45S-52S
Neuroinflammation plays a major role in the etiopathology of neurodegenerative diseases, including Alzheimer and Parkinson diseases, frontotemporal lobar degeneration, and amyotrophic lateral sclerosis. In vivo monitoring of neuroinflammation using P