Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Joseph C, Lamanna"'
Autor:
Yifan Zhang, Kui Xu, Yuchi Liu, Bernadette O Erokwu, Pan Zhao, Chris A Flask, Ciro Ramos-Estebanez, George W Farr, Joseph C LaManna, Walter F Boron, Xin Yu
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218415 (2019)
Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice (AQP4-KO) have reported considerable protection from brain edema indu
Externí odkaz:
https://doaj.org/article/affea4c584254db5b83283ed24ecdffe
Publikováno v:
Ketogenic Diet and Metabolic Therapies ISBN: 0197501206
The brain, unlike other organs, is normally completely dependent on glucose, but is capable of using ketones as an alternate energy source, as occurs with prolonged starvation or chronic feeding of a ketogenic diet (high fat, low carbohydrate). Over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1a5eebb2ae4aed078090d439371e4c
https://doi.org/10.1093/med/9780197501207.003.0026
https://doi.org/10.1093/med/9780197501207.003.0026
Publikováno v:
Advances in experimental medicine and biology. 1269
The mammalian brain modulates its microvascular network to accommodate tissue energy demand in a process referred to as angioplasticity. There is an aging effect on cognitive function and adaptive responses to hypoxia. Hypoxia-induced angiogenesis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0532b6596e3b73c28db442464c8513e
https://pubmed.ncbi.nlm.nih.gov/33966238
https://pubmed.ncbi.nlm.nih.gov/33966238
Publikováno v:
Advances in experimental medicine and biology. 1269
We have previously reported that in a rat model of chronic hypoxia, HIF-1α and its target genes have significantly accumulated by 3 days of exposure, whereas no significant increase in capillary density has occurred; there is a significant increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::682cf6f6b45fc8fd3d6741256cdd04cf
https://pubmed.ncbi.nlm.nih.gov/33966236
https://pubmed.ncbi.nlm.nih.gov/33966236
Publikováno v:
Advances in experimental medicine and biology. 1269
Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate in mice for HIF-1 and HIF-2. The objective of this study was to investigate the effect of neuronal deletion of HIF-1 and HIF-2 in hypoxic adaptation by using the neuron-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f0a12f8b7302a88b75a30f247b84f31
https://pubmed.ncbi.nlm.nih.gov/33966229
https://pubmed.ncbi.nlm.nih.gov/33966229
This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medi
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030482367
The mammalian brain modulates its microvascular network to accommodate tissue energy demand in a process referred to as angioplasticity. There is an aging effect on cognitive function and adaptive responses to hypoxia. Hypoxia-induced angiogenesis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fafbb4783eeb6b545894460b86e263
https://doi.org/10.1007/978-3-030-48238-1_52
https://doi.org/10.1007/978-3-030-48238-1_52
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030482367
Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate in mice for HIF-1 and HIF-2. The objective of this study was to investigate the effect of neuronal deletion of HIF-1 and HIF-2 in hypoxic adaptation by using the neuron-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c105a4df566f1f367329c986bfc922fa
https://doi.org/10.1007/978-3-030-48238-1_43
https://doi.org/10.1007/978-3-030-48238-1_43
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030482367
Hypoxia inducible factor alpha (HIF1α) is associated with neuroprotection conferred by diet-induced ketosis, but the underlying mechanism remains unclear. In this study, we use a ketogenic diet in rodents to induce a metabolic state of chronic ketos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1d9a4e15648308bcb0fd8e93693aeb3
https://doi.org/10.1007/978-3-030-48238-1_1
https://doi.org/10.1007/978-3-030-48238-1_1
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030482367
We have previously reported that in a rat model of chronic hypoxia, HIF-1α and its target genes have significantly accumulated by 3 days of exposure, whereas no significant increase in capillary density has occurred; there is a significant increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6654e40673cb326f9591931383ecdd14
https://doi.org/10.1007/978-3-030-48238-1_50
https://doi.org/10.1007/978-3-030-48238-1_50