Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Joseph C, Devlin"'
Autor:
Ellie N. Ivanova, Jasmine Shwetar, Joseph C. Devlin, Terkild B. Buus, Sophie Gray-Gaillard, Akiko Koide, Amber Cornelius, Marie I. Samanovic, Alberto Herrera, Eleni P. Mimitou, Chenzhen Zhang, Trishala Karmacharya, Ludovic Desvignes, Niels Ødum, Peter Smibert, Robert J. Ulrich, Mark J. Mulligan, Shohei Koide, Kelly V. Ruggles, Ramin S. Herati, Sergei B. Koralov
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108572- (2023)
Summary: SARS-CoV-2 infection and vaccination elicit potent immune responses. Our study presents a comprehensive multimodal single-cell analysis of blood from COVID-19 patients and healthy volunteers receiving the SARS-CoV-2 vaccine and booster. We p
Externí odkaz:
https://doaj.org/article/7cfa8f0f1d8949ed9f5a4be014f10380
Autor:
Amicha Robertson, Joseph Sall, Mericien Venzon, Janet J Olivas, Xuhui Zheng, Michael Cammer, Noelle Antao, Chunyi Zhou, Joseph C Devlin, Rafaela Saes Thur, Jeffrey Bethony, Peter Nejsum, Bo Shopsin, Victor J Torres, Feng-Xia Liang, Ken Cadwell
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011647 (2023)
The bacterial microbiota promotes the life cycle of the intestine-dwelling whipworm Trichuris by mediating hatching of parasite eggs ingested by the mammalian host. Despite the enormous disease burden associated with Trichuris colonization, the mecha
Externí odkaz:
https://doaj.org/article/cc392483bb274eae93333f24cf78f713
Autor:
Menghan Liu, Joseph C Devlin, Jiyuan Hu, Angelina Volkova, Thomas W Battaglia, Melody Ho, John R Asplin, Allyson Byrd, P'ng Loke, Huilin Li, Kelly V Ruggles, Aristotelis Tsirigos, Martin J Blaser, Lama Nazzal
Publikováno v:
eLife, Vol 10 (2021)
Over-accumulation of oxalate in humans may lead to nephrolithiasis and nephrocalcinosis. Humans lack endogenous oxalate degradation pathways (ODP), but intestinal microbes can degrade oxalate using multiple ODPs and protect against its absorption. Th
Externí odkaz:
https://doaj.org/article/799afee30bd04a639dcdd3479eee4bfb
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Exploration of large data sets, such as shotgun metagenomic sequence or expression data, by biomedical experts and medical professionals remains as a major bottleneck in the scientific discovery process. Although tools for this pu
Externí odkaz:
https://doaj.org/article/2b57d876e12d49f697a36cc69cbc1ccb
Autor:
Denis G. Loredan, Joseph C. Devlin, Keenan A. Lacey, Nina Howard, Ze Chen, Erin E. Zwack, Jian-Da Lin, Kelly V. Ruggles, Kamal M. Khanna, Victor J. Torres, P’ng Loke
Publikováno v:
bioRxiv
Our previous studies identified a population of stem cell-like proliferating myeloid cells within inflamed tissues that could serve as a reservoir for tissue macrophages to adopt different activation states depending on the microenvironment. By linea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b666ba0a49024372456f3e1f97f5944c
https://europepmc.org/articles/PMC10002671/
https://europepmc.org/articles/PMC10002671/
Autor:
Erin E. Zwack, Ze Chen, Joseph C. Devlin, Zhi Li, Xuhui Zheng, Ada Weinstock, Keenan A. Lacey, Edward A. Fisher, David Fenyö, Kelly V. Ruggles, P’ng Loke, Victor J. Torres
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Staphylococcus aureusis an opportunistic pathogen and chief among bloodstream-infecting bacteria.S. aureusproduces an array of human-specific virulence factors that may contribute to immune suppression. Here, we defined the response of primary human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb10e9ea359010c238bd0203352912f3
https://doi.org/10.1073/pnas.2123017119
https://doi.org/10.1073/pnas.2123017119
Autor:
Shushan Sargsian, Ze Chen, Soo Ching Lee, Amicha Robertson, Rafaela Saes Thur, Julia Sproch, Joseph C. Devlin, Mian Zi Tee, Yi Xian Er, Richard Copin, Adriana Heguy, Alejandro Pironti, Victor J. Torres, Kelly V. Ruggles, Yvonne A.L. Lim, Jeffrey Bethony, P’ng Loke, Ken Cadwell
Publikováno v:
Cell reports. 41(9)
Soil-transmitted intestinal worms known as helminths colonize over 1.5 billion people worldwide. Although helminth colonization has been associated with altered composition of the gut microbiota, such as increases in Clostridia, individual species ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00074bb60fbd88afdb35ee62eb40c3a
https://pubmed.ncbi.nlm.nih.gov/36450245
https://pubmed.ncbi.nlm.nih.gov/36450245
Autor:
Joseph C. Devlin, Dalia Barkley, Florian Wagner, Cristina H. Hajdu, Reuben Moncada, Maayan Baron, Itai Yanai, Diane M. Simeone, Marta Chiodin
Publikováno v:
Nature Biotechnology. 38:333-342
Single-cell RNA sequencing (scRNA-seq) enables the systematic identification of cell populations in a tissue, but characterizing their spatial organization remains challenging. We combine a microarray-based spatial transcriptomics method that reveals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae79029da72e45c87cfb74ce594c42b2
https://doi.org/10.1038/s41587-019-0392-8
https://doi.org/10.1038/s41587-019-0392-8
Autor:
Shushan Sargsian, Ze Chen, Soo Ching Lee, Amicha Robertson, Julia Sproch, Joseph C. Devlin, Mian Zi Tee, Yi Xian Er, Richard Copin, Adriana Heguy, Alejandro Pironti, Victor J. Torres, Kelly V. Ruggles, Yvonne A.L. Lim, P’ng Loke, Ken Cadwell
Soil transmitted intestinal worms known as helminths colonize over 1.5 billion people worldwide. Although helminth colonization has been associated with altered composition of the gut microbiota, such as increases in Clostridia, individual species ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dec19c6bdae5d755b1ef35fd5e1b4964
https://doi.org/10.1101/2022.02.10.479991
https://doi.org/10.1101/2022.02.10.479991
Autor:
Joseph C. Devlin, Ellie Ivanova, Joseph John Binder, Rachel A Prescott, Annaliesa S. Anderson, Claire M. Steppan, Ana M. Valero-Jimenez, Alberto Herrera, Austin Schinlever, Meike Dittmann, Kelly V. Ruggles, Paige Loose, Adil Mohamed, Ludovic Desvignes, Sergei B. Koralov, Rebecca E. O’Connor, Maren de Vries
Publikováno v:
Journal of Virology. 95
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of Coronavirus Disease 2019 (COVID-19). There is a dire need for novel effective antivirals to treat COVID-19, as the only approved direct-acting antiviral to date
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea53373c54a9220d70405d71a78a5dc8
https://doi.org/10.1128/jvi.01819-20
https://doi.org/10.1128/jvi.01819-20